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leuA-2 leuA-2 argD argD argB argB argJ argJ argC argC aspC aspC MTES_0672 MTES_0672 MTES_0687 MTES_0687 MTES_1061 MTES_1061 MTES_1307 MTES_1307 MTES_1395 MTES_1395 MTES_1396 MTES_1396 aspC-2 aspC-2 lysC lysC asd asd gltA gltA ilvD ilvD ilvB ilvB ilvH ilvH ilvC ilvC leuB leuB ilvE ilvE leuC leuC leuD leuD leuA leuA acnA acnA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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leuA-2Isopropylmalate/homocitrate/citramalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (573 aa)
argDOrnithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (300 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (385 aa)
argCAcetylglutamate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (349 aa)
aspCAspartate/tyrosine/aromatic aminotransferase. (408 aa)
MTES_0672Thiamine pyrophosphate-requiring enzyme; Belongs to the TPP enzyme family. (552 aa)
MTES_0687Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa)
MTES_1061N-acetylglutamate synthase; Belongs to the acetyltransferase family. (169 aa)
MTES_1307Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain. (396 aa)
MTES_1395Citrate synthase; Belongs to the citrate synthase family. (365 aa)
MTES_1396Citrate synthase. (392 aa)
aspC-2Aspartate/tyrosine/aromatic aminotransferase. (399 aa)
lysCAspartokinase; Belongs to the aspartokinase family. (428 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (356 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (431 aa)
ilvDDihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (572 aa)
ilvBThiamine pyrophosphate-requiring enzyme. (602 aa)
ilvHAcetolactate synthase, small (regulatory) subunit. (169 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
leuBIsocitrate/isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (349 aa)
ilvEBranched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (368 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (491 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa)
leuAIsopropylmalate/homocitrate/citramalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (586 aa)
acnAAconitase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (946 aa)
Your Current Organism:
Microbacterium testaceum
NCBI taxonomy Id: 979556
Other names: M. testaceum StLB037, Microbacterium testaceum StLB037, Microbacterium testaceum str. StLB037, Microbacterium testaceum strain StLB037
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