17 items (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	ENSECAP00000032632	Uncharacterized protein. (158 aa)
	ENSECAP00000034592	Uncharacterized protein. (191 aa)
	LOC100060815	Uncharacterized protein. (1051 aa)
	MBP	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). (349 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (377 aa)
	ACTL8	Actin like 8; Belongs to the actin family. (366 aa)
	ACTBL2	Actin beta like 2. (376 aa)
	AQP4	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (319 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (559 aa)
	F6ZRH8_HORSE	Uncharacterized protein. (927 aa)
	NFASC	Neurofascin. (1646 aa)
	ND4	NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (459 aa)
	ACTG1	Actin gamma 1. (462 aa)
	CFL1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
	RBPMS	RNA binding protein, mRNA processing factor. (219 aa)
	APP	Amyloid beta precursor protein. (811 aa)
	LOC111771285	Uncharacterized protein. (195 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTBL2	ENSECAP00000013637	ENSECAP00000002991	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Actin beta like 2.	0.551
ACTB	APP	ENSECAP00000013637	ENSECAP00000019519	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Amyloid beta precursor protein.	0.451
ACTB	AQP4	ENSECAP00000013637	ENSECAP00000003378	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.499
ACTB	CFL1	ENSECAP00000013637	ENSECAP00000017389	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.962
ACTB	GFAP	ENSECAP00000013637	ENSECAP00000008384	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.820
ACTB	MBP	ENSECAP00000013637	ENSECAP00000048300	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).	0.674
ACTBL2	ACTB	ENSECAP00000002991	ENSECAP00000013637	Actin beta like 2.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.551
ACTBL2	CFL1	ENSECAP00000002991	ENSECAP00000017389	Actin beta like 2.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.442
ACTG1	CFL1	ENSECAP00000016149	ENSECAP00000017389	Actin gamma 1.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.520
ACTL8	CFL1	ENSECAP00000002481	ENSECAP00000017389	Actin like 8; Belongs to the actin family.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.437
APP	ACTB	ENSECAP00000019519	ENSECAP00000013637	Amyloid beta precursor protein.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.451
APP	GFAP	ENSECAP00000019519	ENSECAP00000008384	Amyloid beta precursor protein.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.647
APP	MBP	ENSECAP00000019519	ENSECAP00000048300	Amyloid beta precursor protein.	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).	0.425
AQP4	ACTB	ENSECAP00000003378	ENSECAP00000013637	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.499
AQP4	GFAP	ENSECAP00000003378	ENSECAP00000008384	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.942
AQP4	MBP	ENSECAP00000003378	ENSECAP00000048300	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).	0.673
CFL1	ACTB	ENSECAP00000017389	ENSECAP00000013637	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.962
CFL1	ACTBL2	ENSECAP00000017389	ENSECAP00000002991	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Actin beta like 2.	0.442
CFL1	ACTG1	ENSECAP00000017389	ENSECAP00000016149	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Actin gamma 1.	0.520
CFL1	ACTL8	ENSECAP00000017389	ENSECAP00000002481	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Actin like 8; Belongs to the actin family.	0.437