34 items (Equus caballus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (353 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	LOC100071675	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
	FMO4	Dimethylaniline monooxygenase [N-oxide-forming]. (571 aa)
	LOC100071699	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (381 aa)
	CCDC112	Coiled-coil domain containing 112. (527 aa)
	COQ10A	Coenzyme Q10A. (240 aa)
	PGGT1B	Protein geranylgeranyltransferase type I subunit beta. (377 aa)
	DHDDS	Alkyl transferase; Belongs to the UPP synthase family. (383 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (370 aa)
	FBXO30	F-box protein 30. (813 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (299 aa)
	GRAMD1C	GRAM domain containing 1C. (660 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (379 aa)
	FMO5	Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
	COQ8A	Coenzyme Q8A. (635 aa)
	FMO1	Flavin-containing monooxygenase. (1023 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (408 aa)
	COQ8B	Coenzyme Q8B. (541 aa)
	AADAC-2	Arylacetamide deacetylase. (278 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (296 aa)
	PDSS2	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (410 aa)
	GRAMD1A	GRAM domain containing 1A. (807 aa)
	LOC100050840	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (575 aa)
	COQ9	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (336 aa)
	LOC100060824	Dimethylaniline monooxygenase [N-oxide-forming]. (516 aa)
	ADCK2	AarF domain containing kinase 2. (650 aa)
	COQ2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (391 aa)
	RCE1	Ras converting CAAX endopeptidase 1. (590 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (547 aa)
	AADAC	Arylacetamide deacetylase. (399 aa)
	FNTB	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (513 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAC	GRAMD1A	ENSECAP00000048226	ENSECAP00000023949	Arylacetamide deacetylase.	GRAM domain containing 1A.	0.770
AADAC	GRAMD1C	ENSECAP00000048226	ENSECAP00000015727	Arylacetamide deacetylase.	GRAM domain containing 1C.	0.770
AADAC	LOC100050840	ENSECAP00000048226	ENSECAP00000024774	Arylacetamide deacetylase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.712
AADAC-2	GRAMD1A	ENSECAP00000021563	ENSECAP00000023949	Arylacetamide deacetylase.	GRAM domain containing 1A.	0.770
AADAC-2	GRAMD1C	ENSECAP00000021563	ENSECAP00000015727	Arylacetamide deacetylase.	GRAM domain containing 1C.	0.770
AADAC-2	LOC100050840	ENSECAP00000021563	ENSECAP00000024774	Arylacetamide deacetylase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.712
ADCK2	COQ3	ENSECAP00000040032	ENSECAP00000014514	AarF domain containing kinase 2.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.754
ADCK2	COQ5	ENSECAP00000040032	ENSECAP00000004398	AarF domain containing kinase 2.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.470
ADCK2	COQ8B	ENSECAP00000040032	ENSECAP00000020021	AarF domain containing kinase 2.	Coenzyme Q8B.	0.648
ADCK2	COQ9	ENSECAP00000040032	ENSECAP00000036870	AarF domain containing kinase 2.	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.	0.461
CCDC112	PGGT1B	ENSECAP00000012689	ENSECAP00000013952	Coiled-coil domain containing 112.	Protein geranylgeranyltransferase type I subunit beta.	0.643
COQ10A	COQ2	ENSECAP00000013563	ENSECAP00000041002	Coenzyme Q10A.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.512
COQ10A	COQ3	ENSECAP00000013563	ENSECAP00000014514	Coenzyme Q10A.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.529
COQ10A	COQ5	ENSECAP00000013563	ENSECAP00000004398	Coenzyme Q10A.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.476
COQ10A	COQ6	ENSECAP00000013563	ENSECAP00000045267	Coenzyme Q10A.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.760
COQ10A	COQ7	ENSECAP00000013563	ENSECAP00000019486	Coenzyme Q10A.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	0.419
COQ10A	COQ8A	ENSECAP00000013563	ENSECAP00000017787	Coenzyme Q10A.	Coenzyme Q8A.	0.568
COQ10A	PDSS2	ENSECAP00000013563	ENSECAP00000022908	Coenzyme Q10A.	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.	0.843
COQ2	COQ10A	ENSECAP00000041002	ENSECAP00000013563	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Coenzyme Q10A.	0.512
COQ2	COQ3	ENSECAP00000041002	ENSECAP00000014514	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.904