(38 nodes) Ether lipid metabolism, and Glycerophospholipid metabolism network (Equus caballus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	LPCAT2	Lysophosphatidylcholine acyltransferase 2. (544 aa)
	PAFAH1B3	Platelet activating factor acetylhydrolase 1b catalytic subunit 3. (231 aa)
	PLA2G2A	Phospholipase A(2). (144 aa)
	PNPLA6	Patatin like phospholipase domain containing 6. (1362 aa)
	PLD3	Phospholipase D family member 3. (490 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
	PLD2	Phospholipase. (933 aa)
	STMN1	Platelet-activating factor acetylhydrolase. (392 aa)
	PLA2G2E	Phospholipase A(2). (142 aa)
	PTDSS1	Phosphatidylserine synthase 1. (473 aa)
	PLA2G10	Phospholipase A(2). (160 aa)
	PLB1	Phospholipase B1. (1456 aa)
	PLAAT3	Phospholipase A and acyltransferase 3. (162 aa)
	PEMT	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (322 aa)
	PLA2G2F	Phospholipase A(2). (210 aa)
	LPCAT1	Lysophosphatidylcholine acyltransferase 1. (764 aa)
	PTDSS2	Phosphatidylserine synthase 2. (498 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (440 aa)
	LPCAT4	Lysophosphatidylcholine acyltransferase 4. (517 aa)
	GPCPD1	Glycerophosphocholine phosphodiesterase 1. (685 aa)
	LPCAT3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (486 aa)
	PLA2G3	Phospholipase A2 group III. (513 aa)
	LYPLA2	Lysophospholipase 2. (281 aa)
	LOC100053989	LRAT domain-containing protein. (287 aa)
	PLA2G7	Platelet-activating factor acetylhydrolase. (512 aa)
	PLD4	Phospholipase D family member 4. (515 aa)
	PISD	Phosphatidylserine decarboxylase. (417 aa)
	LCLAT1	Lysocardiolipin acyltransferase 1. (376 aa)
	PLA2G4A	Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response. (749 aa)
	PLA2G2D	Phospholipase A(2). (145 aa)
	ENSECAP00000038879	Uncharacterized protein. (494 aa)
	PNPLA7	Patatin like phospholipase domain containing 7. (1351 aa)
	PAFAH1B2	Platelet-activating factor acetylhydrolase I subunit beta-like protein. (229 aa)
	LYPLA1	Lysophospholipase 1. (230 aa)
	LPGAT1	Lysophosphatidylglycerol acyltransferase 1. (467 aa)
	PLD1	Phospholipase. (1189 aa)
	MBOAT1	Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (506 aa)
	ENSECAP00000045695	LRAT domain-containing protein. (137 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSECAP00000038879	ENSECAP00000045695	ENSECAP00000038879	ENSECAP00000045695	Uncharacterized protein.	LRAT domain-containing protein.	0.902
ENSECAP00000038879	LCLAT1	ENSECAP00000038879	ENSECAP00000029493	Uncharacterized protein.	Lysocardiolipin acyltransferase 1.	0.914
ENSECAP00000038879	LOC100053989	ENSECAP00000038879	ENSECAP00000026808	Uncharacterized protein.	LRAT domain-containing protein.	0.902
ENSECAP00000038879	LPCAT1	ENSECAP00000038879	ENSECAP00000019282	Uncharacterized protein.	Lysophosphatidylcholine acyltransferase 1.	0.904
ENSECAP00000038879	LPCAT2	ENSECAP00000038879	ENSECAP00000007817	Uncharacterized protein.	Lysophosphatidylcholine acyltransferase 2.	0.902
ENSECAP00000038879	LPCAT4	ENSECAP00000038879	ENSECAP00000020494	Uncharacterized protein.	Lysophosphatidylcholine acyltransferase 4.	0.935
ENSECAP00000038879	LPGAT1	ENSECAP00000038879	ENSECAP00000043154	Uncharacterized protein.	Lysophosphatidylglycerol acyltransferase 1.	0.914
ENSECAP00000038879	LYPLA1	ENSECAP00000038879	ENSECAP00000042613	Uncharacterized protein.	Lysophospholipase 1.	0.652
ENSECAP00000038879	PAFAH1B1	ENSECAP00000038879	ENSECAP00000012312	Uncharacterized protein.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.900
ENSECAP00000038879	PAFAH1B2	ENSECAP00000038879	ENSECAP00000041709	Uncharacterized protein.	Platelet-activating factor acetylhydrolase I subunit beta-like protein.	0.905
ENSECAP00000038879	PAFAH1B3	ENSECAP00000038879	ENSECAP00000008799	Uncharacterized protein.	Platelet activating factor acetylhydrolase 1b catalytic subunit 3.	0.905
ENSECAP00000038879	PEMT	ENSECAP00000038879	ENSECAP00000018017	Uncharacterized protein.	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.	0.911
ENSECAP00000038879	PLA2G10	ENSECAP00000038879	ENSECAP00000014173	Uncharacterized protein.	Phospholipase A(2).	0.656
ENSECAP00000038879	PLA2G2A	ENSECAP00000038879	ENSECAP00000009153	Uncharacterized protein.	Phospholipase A(2).	0.658
ENSECAP00000038879	PLA2G2D	ENSECAP00000038879	ENSECAP00000031084	Uncharacterized protein.	Phospholipase A(2).	0.673
ENSECAP00000038879	PLA2G2E	ENSECAP00000038879	ENSECAP00000013891	Uncharacterized protein.	Phospholipase A(2).	0.656
ENSECAP00000038879	PLA2G2F	ENSECAP00000038879	ENSECAP00000018404	Uncharacterized protein.	Phospholipase A(2).	0.656
ENSECAP00000038879	PLA2G3	ENSECAP00000038879	ENSECAP00000022634	Uncharacterized protein.	Phospholipase A2 group III.	0.650
ENSECAP00000038879	PLA2G4A	ENSECAP00000038879	ENSECAP00000030001	Uncharacterized protein.	Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.	0.666
ENSECAP00000038879	PLA2G7	ENSECAP00000038879	ENSECAP00000027952	Uncharacterized protein.	Platelet-activating factor acetylhydrolase.	0.912