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| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (303 aa) |
| | IRS2 | Insulin receptor substrate 2. (1401 aa) |
| | SOCS4 | Suppressor of cytokine signaling 4. (441 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | IRS1 | Insulin receptor substrate 1. (1239 aa) |
| | ALK | Tyrosine-protein kinase receptor. (1623 aa) |
| | EREG | Epiregulin. (170 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | FGR | Tyrosine-protein kinase. (527 aa) |
| | KL | Klotho. (1011 aa) |
| | NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) |
| | ANGPT4 | Angiopoietin 4. (497 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (294 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | TGFA | Transforming growth factor alpha. (221 aa) |
| | SRMS | Tyrosine-protein kinase. (491 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1209 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | IRS4 | Insulin receptor substrate 4. (1355 aa) |
| | PTPRZ1 | Protein tyrosine phosphatase receptor type Z1. (2327 aa) |
| | SRC | Tyrosine-protein kinase. (551 aa) |
| | KIT | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa) |
| | CSK | Tyrosine-protein kinase. (549 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1334 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (918 aa) |
| | FGF5 | Fibroblast growth factor 5. (280 aa) |
| | BLNK | B cell linker. (467 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | TEK | TEK receptor tyrosine kinase. (1153 aa) |
| | NGFR | Nerve growth factor receptor. (435 aa) |
| | HCK | Tyrosine-protein kinase. (525 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | KHDRBS1 | KH RNA binding domain containing, signal transduction associated 1. (443 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (368 aa) |
| | GRAP2 | GRB2 related adaptor protein 2. (316 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1358 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa) |
| | LAT | Linker for activation of T cells. (238 aa) |
| | BTK | Tyrosine-protein kinase. (687 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | LCP2 | Lymphocyte cytosolic protein 2. (533 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | YES1 | Tyrosine-protein kinase. (583 aa) |
| | AREG | Amphiregulin. (247 aa) |
| | DOK1 | Docking protein 1. (481 aa) |
| | LOC100146191 | Uncharacterized protein. (581 aa) |
| | KLB | Klotho beta. (1045 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | ROS1 | Tyrosine-protein kinase receptor. (2342 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (830 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1339 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (606 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (240 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1366 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1336 aa) |
| | NRG4 | Neuregulin 4. (116 aa) |
| | PIK3R2 | Uncharacterized protein. (479 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa) |
| | PTPN1 | Protein tyrosine phosphatase non-receptor type 1. (493 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (249 aa) |
| | LOC100050401 | SH2 domain-containing protein. (266 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1093 aa) |
| | PDGFD | Platelet derived growth factor D. (566 aa) |
| | PTN | Pleiotrophin. (192 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | FLT3LG | Fms related tyrosine kinase 3 ligand. (241 aa) |
| | MDK | Uncharacterized protein. (440 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | CBLB | Cbl proto-oncogene B. (1189 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa) |
| | NRG2 | Neuregulin 2. (923 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | FGF12 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa) |
| | LOC100052122 | Uncharacterized protein. (461 aa) |
| | SH2B2 | SH2B adaptor protein 2. (873 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1331 aa) |
| | SOCS2 | Suppressor of cytokine signaling 2. (270 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | ENSECAP00000033804 | Uncharacterized protein. (1210 aa) |
| | GAB1 | GRB2 associated binding protein 1. (771 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (880 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | FGFRL1 | Fibroblast growth factor receptor like 1. (522 aa) |
| | EML4 | EMAP like 4. (1006 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (863 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (299 aa) |
| | GAB2 | GRB2 associated binding protein 2. (708 aa) |
| | SYK | Tyrosine-protein kinase. (716 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (515 aa) |
| | LOC100069009 | Uncharacterized protein. (571 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1399 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | LOC100068923 | Uncharacterized protein. (212 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (231 aa) |
| | KIDINS220 | Kinase D interacting substrate 220. (1785 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa) |
| | FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (278 aa) |
| | LYN | Tyrosine-protein kinase. (533 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1465 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (834 aa) |
| | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (434 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | LTK | Tyrosine-protein kinase receptor. (891 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (877 aa) |
| | SHC3 | SHC adaptor protein 3. (591 aa) |
| | FYN | Tyrosine-protein kinase. (589 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 6. (890 aa) |
| | BTC | Betacellulin. (188 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (210 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (887 aa) |
| | TEC | Tyrosine-protein kinase. (643 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1020 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (855 aa) |
| | PTPRS | Protein tyrosine phosphatase receptor type S. (1948 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (887 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1613 aa) |
| | EPGN | Epithelial mitogen. (154 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | NRG3 | Neuregulin 3. (727 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (836 aa) |
| | NRG1 | Neuregulin 1. (712 aa) |
