STRINGSTRING
LOXL3 LOXL3 ADAMTS16 ADAMTS16 SERPINH1 SERPINH1 MMP13 MMP13 CRTAP CRTAP P3H2 P3H2 FBLN2 FBLN2 COL14A1 COL14A1 PLOD2 PLOD2 COL21A1 COL21A1 MYOC MYOC COL5A2 COL5A2 COL9A2 COL9A2 C2CD3 C2CD3 COL6A5 COL6A5 CERCAM CERCAM ABCA4 ABCA4 CLEC3A CLEC3A LOX LOX TLL2 TLL2 F6W5N9_HORSE F6W5N9_HORSE NCAN NCAN COL6A6 COL6A6 HAPLN1 HAPLN1 ADAMTS1 ADAMTS1 COL18A1 COL18A1 MATN3 MATN3 PPIB PPIB MATN4 MATN4 COL25A1 COL25A1 COLGALT2 COLGALT2 HYAL3 HYAL3 LUM LUM TNMD TNMD AREL1 AREL1 MMP27 MMP27 COL8A1 COL8A1 CNMD CNMD COL6A2 COL6A2 FBN1 FBN1 SP7 SP7 DCN DCN LTBP1 LTBP1 COL10A1 COL10A1 COL15A1 COL15A1 PCOLCE PCOLCE SOX9 SOX9 P3H3 P3H3 ADAMTS6 ADAMTS6 BMP1 BMP1 SERPINF1 SERPINF1 PLOD3 PLOD3 P3H1 P3H1 PLOD1 PLOD1 COL9A3 COL9A3 NIBAN3 NIBAN3 LOXL1 LOXL1 COL24A1 COL24A1 BGLAP BGLAP POSTN POSTN ADAMTS4 ADAMTS4 COL16A1 COL16A1 COL3A1 COL3A1 COL1A2 COL1A2 LOXL2 LOXL2 BCAN BCAN COL6A1 COL6A1 FBLN1 FBLN1 LTBP3 LTBP3 RUNX2 RUNX2 FMOD FMOD MFAP5 MFAP5 CD248 CD248 TGFB3 TGFB3 LTBP4 LTBP4 EPYC EPYC MFAP4 MFAP4 FBLN5 FBLN5 COL8A2 COL8A2 COL12A1 COL12A1 P3H4 P3H4 COMP COMP ACAN ACAN COL13A1 COL13A1 BGN BGN SLC2A10 SLC2A10 MKX MKX COL20A1 COL20A1 COL2A1 COL2A1 COL22A1 COL22A1 COL5A1 COL5A1 TGFB2 TGFB2 COL6A3 COL6A3 VCAN VCAN COL9A1 COL9A1 COL11A2 COL11A2 VIT VIT COL11A1 COL11A1 ADAMTS5 ADAMTS5 ELN ELN COL26A1 COL26A1 COL1A1 COL1A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOXL3Lysyl oxidase like 3. (796 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1245 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
MMP13Collagenase 3; Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bon [...] (472 aa)
CRTAPCartilage associated protein. (401 aa)
P3H2Prolyl 3-hydroxylase 2. (697 aa)
FBLN2Fibulin 2. (1230 aa)
COL14A1Collagen type XIV alpha 1 chain. (1796 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa)
COL21A1Collagen type XXI alpha 1 chain. (967 aa)
MYOCMyocilin. (490 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
COL9A2Collagen type IX alpha 2 chain. (688 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2342 aa)
COL6A5Collagen type VI alpha 5 chain. (1758 aa)
CERCAMCerebral endothelial cell adhesion molecule. (594 aa)
ABCA4ATP binding cassette subfamily A member 4. (2268 aa)
CLEC3AC-type lectin domain family 3 member A. (196 aa)
LOXLysyl oxidase. (481 aa)
TLL2Metalloendopeptidase. (1020 aa)
F6W5N9_HORSEVWFA domain-containing protein. (439 aa)
NCANNeurocan. (1365 aa)
COL6A6Collagen type VI alpha 6 chain. (2272 aa)
HAPLN1Hyaluronan and proteoglycan link protein 1; Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix; Belongs to the HAPLN family. (354 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (966 aa)
COL18A1Collagen type XVIII alpha 1 chain. (1752 aa)
MATN3Matrilin 3. (475 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
MATN4Matrilin 4. (621 aa)
COL25A1Collagen type XXV alpha 1 chain. (654 aa)
COLGALT2Collagen beta(1-O)galactosyltransferase 2. (626 aa)
HYAL3Hyaluronidase. (415 aa)
LUMLumican. (341 aa)
TNMDTenomodulin. (317 aa)
AREL1Latent transforming growth factor beta binding protein 2. (1819 aa)
MMP27Matrix metallopeptidase 27. (511 aa)
COL8A1Collagen type VIII alpha 1 chain. (735 aa)
CNMDChondromodulin. (334 aa)
COL6A2Collagen type VI alpha 2 chain. (1018 aa)
FBN1Fibrillin 1. (3030 aa)
SP7Sp7 transcription factor. (431 aa)
DCNDecorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1715 aa)
COL10A1Collagen type X alpha 1 chain. (674 aa)
COL15A1Collagen type XV alpha 1 chain. (1388 aa)
PCOLCEProcollagen C-endopeptidase enhancer. (459 aa)
SOX9SRY-box 9. (509 aa)
P3H3Prolyl 3-hydroxylase 3. (731 aa)
ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif 6. (1117 aa)
BMP1Metalloendopeptidase. (1083 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (417 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (743 aa)
P3H1Prolyl 3-hydroxylase 1. (732 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (727 aa)
COL9A3Collagen type IX alpha 3 chain. (682 aa)
NIBAN3Niban apoptosis regulator 3. (623 aa)
LOXL1Lysyl oxidase like 1. (578 aa)
COL24A1Collagen type XXIV alpha 1 chain. (1709 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa)
POSTNPeriostin. (836 aa)
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (837 aa)
COL16A1Collagen type XVI alpha 1 chain. (1612 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
COL1A2Collagen type I alpha 2 chain. (1364 aa)
LOXL2Lysyl oxidase like 2. (1047 aa)
BCANBrevican. (981 aa)
COL6A1Collagen type VI alpha 1 chain. (1027 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (753 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1554 aa)
RUNX2Runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation. In osteoblasts, supports transcription activati [...] (634 aa)
FMODFibromodulin. (392 aa)
MFAP5Uncharacterized protein. (275 aa)
CD248CD248 molecule. (773 aa)
TGFB3Transforming growth factor beta 3. (490 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1708 aa)
EPYCEpiphycan. (322 aa)
MFAP4Microfibril associated protein 4. (271 aa)
FBLN5Fibulin 5. (516 aa)
COL8A2Collagen type VIII alpha 2 chain. (786 aa)
COL12A1Collagen type XII alpha 1 chain. (3120 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (502 aa)
COMPCartilage oligomeric matrix protein. (793 aa)
ACANAggrecan. (2703 aa)
COL13A1Collagen type XIII alpha 1 chain. (716 aa)
BGNBiglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (460 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (558 aa)
MKXMohawk homeobox. (352 aa)
COL20A1Collagen type XX alpha 1 chain. (1320 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
COL22A1VWFA domain-containing protein. (1328 aa)
COL5A1Collagen type V alpha 1 chain. (1813 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
COL6A3Collagen type VI alpha 3 chain. (3166 aa)
VCANVersican. (3400 aa)
COL9A1Collagen type IX alpha 1 chain. (919 aa)
COL11A2Collagen type XI alpha 2 chain. (1736 aa)
VITVitrin. (694 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (929 aa)
ELNUncharacterized protein. (1088 aa)
COL26A1Collagen type XXVI alpha 1 chain. (570 aa)
COL1A1Collagen type I alpha 1 chain. (1521 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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