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| | PRL | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. (234 aa) |
| | LOC100629870 | Uncharacterized protein. (196 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (388 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (229 aa) |
| | IFND2 | Uncharacterized protein. (170 aa) |
| | LOC100053263 | Uncharacterized protein. (195 aa) |
| | LOC100071430 | Uncharacterized protein. (191 aa) |
| | IL17RB | Interleukin 17 receptor B. (499 aa) |
| | IL28B | Uncharacterized protein. (189 aa) |
| | THPO | Thrombopoietin. (350 aa) |
| | IL17B | Interleukin 17B. (180 aa) |
| | IFNB1 | Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa) |
| | CNTFR | Ciliary neurotrophic factor receptor. (372 aa) |
| | LOC100053210 | Uncharacterized protein. (184 aa) |
| | LOC100629859 | Uncharacterized protein. (195 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (386 aa) |
| | IL20RA | Interleukin 20 receptor subunit alpha. (503 aa) |
| | EPOR | Erythropoietin receptor; Receptor for erythropoietin. (509 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (139 aa) |
| | CSF3 | Colony stimulating factor 3. (204 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (249 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | GH1 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (216 aa) |
| | MAP3K21 | Mitogen-activated protein kinase kinase kinase. (1053 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (472 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor. (152 aa) |
| | IL17RC | Interleukin 17 receptor C. (718 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (625 aa) |
| | IL13 | Interleukin-13. (133 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (225 aa) |
| | JAK2 | Tyrosine-protein kinase. (1131 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (561 aa) |
| | LOC111769802 | Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP) (By similarity); Belongs to the type I cytokine receptor family. Type 4 subfamily. (458 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (650 aa) |
| | IL24 | Interleukin 24. (206 aa) |
| | LOC100069576 | Fibronectin type-III domain-containing protein. (823 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (329 aa) |
| | IFNLR1 | Interferon lambda receptor 1. (518 aa) |
| | CSF3R | Colony stimulating factor 3 receptor. (1068 aa) |
| | IL11 | Interleukin 11. (246 aa) |
| | IL17RE | Interleukin 17 receptor E. (701 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (572 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (158 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (149 aa) |
| | IL2RB | Interleukin 2 receptor subunit beta. (558 aa) |
| | IL22RA1 | Interleukin 22 receptor subunit alpha 1. (581 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (231 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (906 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | IL31RA | Interleukin 31 receptor A. (734 aa) |
| | IL17RA | Interleukin 17 receptor A. (866 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (631 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | IL31 | Interleukin 31. (156 aa) |
| | IRF3 | Interferon regulatory factor 3. (426 aa) |
| | EBI3 | Epstein-Barr virus induced 3. (227 aa) |
| | IL25 | Interleukin 25. (161 aa) |
| | IL21R | Interleukin 21 receptor. (557 aa) |
| | JAK1 | Tyrosine-protein kinase. (1141 aa) |
| | IL13RA1 | Interleukin 13 receptor subunit alpha 1. (424 aa) |
| | IL22 | Interleukin-22-like protein. (189 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (581 aa) |
| | CSF2RB | Uncharacterized protein. (901 aa) |
| | LIFR | LIF receptor subunit alpha. (1332 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (176 aa) |
| | TYK2 | Tyrosine-protein kinase. (1262 aa) |
| | IFNK | Interferon kappa. (208 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (718 aa) |
| | IL23A | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] (192 aa) |
| | STAT2 | Signal transducer and activator of transcription. (847 aa) |
| | STAT4 | Signal transducer and activator of transcription. (748 aa) |
| | CRLF1 | Cytokine receptor like factor 1. (421 aa) |
| | IL6R | Interleukin 6 receptor. (471 aa) |
| | IRF9 | Interferon regulatory factor 9. (394 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (256 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | IL9R | Interleukin 9 receptor. (499 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (222 aa) |
| | IL9 | Interleukin 9. (147 aa) |
| | GHR | Growth hormone receptor. (646 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (432 aa) |
| | IL6ST | Interleukin 6 signal transducer. (1023 aa) |
| | ENSECAP00000026252 | Uncharacterized protein. (259 aa) |
| | IFN-ALPHA2 | Interferon alpha-2; Produced by macrophages, IFN-alpha have antiviral activities. (184 aa) |
| | LIF | LIF interleukin 6 family cytokine. (203 aa) |
| | OSMR | Oncostatin M receptor. (972 aa) |
| | LOC100147106 | Uncharacterized protein. (195 aa) |
| | ENSECAP00000029579 | SH2 domain-containing protein. (203 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | ENSECAP00000030960 | Uncharacterized protein. (353 aa) |
| | ENSECAP00000031813 | Uncharacterized protein. (282 aa) |
| | IL2RA | Interleukin 2 receptor subunit alpha. (275 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | LOC100052971 | Uncharacterized protein. (195 aa) |
| | IL13RA2 | Interleukin 13 receptor subunit alpha 2. (418 aa) |
| | IL20 | Interleukin 20. (248 aa) |
| | IL19 | Interleukin 19. (165 aa) |
| | STAT5B | Signal transducer and activator of transcription. (825 aa) |
| | LOC102148014 | Uncharacterized protein. (355 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa) |
| | IL26 | Interleukin 26. (180 aa) |
| | ZFP91 | Uncharacterized protein. (688 aa) |
| | LOC100053110 | Interferon alpha-4; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (184 aa) |
| | IL27 | Interleukin 27. (264 aa) |
| | STAT5A | Signal transducer and activator of transcription. (800 aa) |
| | IL17A | Uncharacterized protein. (155 aa) |
| | IL5RA | Interleukin 5 receptor subunit alpha. (480 aa) |
| | JAK3 | Tyrosine-protein kinase. (1139 aa) |
| | IL17F | Interleukin 17F. (154 aa) |
| | IL15RA | Interleukin 15 receptor subunit alpha. (260 aa) |
| | LOC100629951 | Interferon alpha-1; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (184 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (457 aa) |
| | CTF1 | Cardiotrophin 1. (457 aa) |
| | CRLF3 | Cytokine receptor like factor 3. (548 aa) |
| | IRF7 | Interferon regulatory factor 7. (536 aa) |
| | LOC100629885 | Uncharacterized protein. (167 aa) |
| | IFNAR2 | Uncharacterized protein. (530 aa) |
| | NCK1 | Interleukin 20 receptor subunit beta. (484 aa) |
| | LOC100064612 | Uncharacterized protein. (171 aa) |
| | IL4R | Interleukin-4 receptor subunit alpha; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 (By similarity). (831 aa) |
| | IL17C | Interleukin 17C. (197 aa) |
| | LOC100147174 | Uncharacterized protein. (186 aa) |
| | IL17RD | Interleukin 17 receptor D. (742 aa) |
| | LOC111767428 | Interferon omega-1. (195 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (461 aa) |
