(50 nodes) Glycosphingolipid biosynthesis - lacto and neolacto series, and Mucin type O-glycan biosynthesis network (Equus caballus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GCNT2	Glucosaminyl (N-acetyl) transferase 2 (I blood group). (457 aa)
	B3GNT4	Hexosyltransferase. (354 aa)
	B3GNT5	Hexosyltransferase. (380 aa)
	B3GALT1	Hexosyltransferase. (326 aa)
	C1GALT1C1	C1GALT1 specific chaperone 1. (318 aa)
	GCNT3	Glucosaminyl (N-acetyl) transferase 3, mucin type. (428 aa)
	B3GALT5	Hexosyltransferase. (311 aa)
	GCNT4	Glucosaminyl (N-acetyl) transferase 4. (561 aa)
	LOC100054216	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (347 aa)
	LOC100054259	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (346 aa)
	LOC100054308	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (346 aa)
	FUT1	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (370 aa)
	ST6GALNAC1	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (598 aa)
	GALNT7	Polypeptide N-acetylgalactosaminyltransferase. (657 aa)
	ST6GAL2	ST6 beta-galactoside alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (529 aa)
	ST6GALNAC6	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (333 aa)
	GALNT5	Polypeptide N-acetylgalactosaminyltransferase. (940 aa)
	C1GALT1	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (375 aa)
	A4GNT	Alpha-1,4-N-acetylglucosaminyltransferase. (389 aa)
	FUT9	Fucosyltransferase 9. (382 aa)
	ABO	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase. (354 aa)
	B3GNT3	Hexosyltransferase. (372 aa)
	B3GNT2	Hexosyltransferase. (397 aa)
	B3GNT6	Hexosyltransferase. (410 aa)
	GALNT14	Polypeptide N-acetylgalactosaminyltransferase. (552 aa)
	LOC111767452	Uncharacterized protein. (322 aa)
	B3GALT2	Hexosyltransferase. (422 aa)
	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
	RHOV	Ras homolog family member V. (236 aa)
	B4GALT3	Beta-1,4-galactosyltransferase 3. (396 aa)
	LOC100067589	Uncharacterized protein. (538 aa)
	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa)
	GALNT8	Polypeptide N-acetylgalactosaminyltransferase. (637 aa)
	B4GALT2	Beta-1,4-galactosyltransferase 2. (390 aa)
	LOC100065936	Uncharacterized protein. (355 aa)
	ST6GAL1	ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (690 aa)
	GALNT12	Polypeptide N-acetylgalactosaminyltransferase. (580 aa)
	ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (379 aa)
	B4GALT4	Beta-1,4-galactosyltransferase 4. (365 aa)
	GALNT3	Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
	B4GALT1	Beta-1,4-galactosyltransferase 1. (452 aa)
	GCNT1	Uncharacterized protein. (483 aa)
	B3GNT10	Hexosyltransferase. (369 aa)
	GALNT2	Polypeptide N-acetylgalactosaminyltransferase. (598 aa)
	FMN1	Formin 1. (1417 aa)
	FUT4	Fucosyltransferase 4. (390 aa)
	ENSECAP00000040796	Glyco_tran_10_N domain-containing protein. (396 aa)
	SAP30L	Polypeptide N-acetylgalactosaminyltransferase. (678 aa)
	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (402 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4GNT	B3GNT3	ENSECAP00000011572	ENSECAP00000013967	Alpha-1,4-N-acetylglucosaminyltransferase.	Hexosyltransferase.	0.445
A4GNT	B3GNT5	ENSECAP00000011572	ENSECAP00000001287	Alpha-1,4-N-acetylglucosaminyltransferase.	Hexosyltransferase.	0.402
A4GNT	B3GNT6	ENSECAP00000011572	ENSECAP00000016923	Alpha-1,4-N-acetylglucosaminyltransferase.	Hexosyltransferase.	0.445
A4GNT	B4GALT4	ENSECAP00000011572	ENSECAP00000030708	Alpha-1,4-N-acetylglucosaminyltransferase.	Beta-1,4-galactosyltransferase 4.	0.483
A4GNT	C1GALT1	ENSECAP00000011572	ENSECAP00000010739	Alpha-1,4-N-acetylglucosaminyltransferase.	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.	0.830
A4GNT	FUT4	ENSECAP00000011572	ENSECAP00000040532	Alpha-1,4-N-acetylglucosaminyltransferase.	Fucosyltransferase 4.	0.600
A4GNT	GALNT12	ENSECAP00000011572	ENSECAP00000026891	Alpha-1,4-N-acetylglucosaminyltransferase.	Polypeptide N-acetylgalactosaminyltransferase.	0.416
A4GNT	GALNT5	ENSECAP00000011572	ENSECAP00000010297	Alpha-1,4-N-acetylglucosaminyltransferase.	Polypeptide N-acetylgalactosaminyltransferase.	0.461
A4GNT	GCNT1	ENSECAP00000011572	ENSECAP00000036545	Alpha-1,4-N-acetylglucosaminyltransferase.	Uncharacterized protein.	0.508
A4GNT	GCNT3	ENSECAP00000011572	ENSECAP00000002921	Alpha-1,4-N-acetylglucosaminyltransferase.	Glucosaminyl (N-acetyl) transferase 3, mucin type.	0.515
A4GNT	GCNT4	ENSECAP00000011572	ENSECAP00000003812	Alpha-1,4-N-acetylglucosaminyltransferase.	Glucosaminyl (N-acetyl) transferase 4.	0.658
A4GNT	LOC100054259	ENSECAP00000011572	ENSECAP00000004103	Alpha-1,4-N-acetylglucosaminyltransferase.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.465
A4GNT	LOC100054308	ENSECAP00000011572	ENSECAP00000004199	Alpha-1,4-N-acetylglucosaminyltransferase.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.465
A4GNT	ST3GAL4	ENSECAP00000011572	ENSECAP00000054919	Alpha-1,4-N-acetylglucosaminyltransferase.	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family.	0.557
ABO	ENSECAP00000040796	ENSECAP00000012378	ENSECAP00000040796	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase.	Glyco_tran_10_N domain-containing protein.	0.900
ABO	FUT1	ENSECAP00000012378	ENSECAP00000004253	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.905
ABO	FUT9	ENSECAP00000012378	ENSECAP00000012169	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase.	Fucosyltransferase 9.	0.900
ABO	LOC100054216	ENSECAP00000012378	ENSECAP00000003984	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.902
ABO	LOC100054259	ENSECAP00000012378	ENSECAP00000004103	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.902
ABO	LOC100054308	ENSECAP00000012378	ENSECAP00000004199	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.902