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| | GTF2F1 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (557 aa) |
| | POLR2D | RNA polymerase II subunit D. (142 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (599 aa) |
| | POLR2L-2 | RNA polymerase II subunit L. (79 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (323 aa) |
| | MED7 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (267 aa) |
| | GTF2A1 | General transcription factor IIA subunit 1. (376 aa) |
| | MED22 | Mediator complex subunit 22. (200 aa) |
| | F6RBM6_HORSE | TAFII28 domain-containing protein. (199 aa) |
| | PLPPR4 | Phospholipid phosphatase related 4. (763 aa) |
| | POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | SNAPC3 | Small nuclear RNA activating complex polypeptide 3. (412 aa) |
| | TCEANC2 | Transcription elongation factor A N-terminal and central domain containing 2. (208 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | LOC100073305 | General transcription factor IIH subunit. (395 aa) |
| | F6UIV7_HORSE | Uncharacterized protein. (300 aa) |
| | TBP | TATA-box binding protein. (329 aa) |
| | MED25 | Mediator complex subunit 25. (746 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (765 aa) |
| | GTF3C5 | General transcription factor IIIC subunit 5. (523 aa) |
| | RRN3 | RRN3 homolog, RNA polymerase I transcription factor. (651 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa) |
| | ZBTB24 | Zinc finger and BTB domain containing 24. (697 aa) |
| | F7BQV6_HORSE | Uncharacterized protein. (763 aa) |
| | CDK19 | Cyclin dependent kinase 19. (530 aa) |
| | SNAPC5 | Small nuclear RNA activating complex polypeptide 5. (97 aa) |
| | POLR3F | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa) |
| | POLR1B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1165 aa) |
| | MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (314 aa) |
| | GTF3C1 | General transcription factor IIIC subunit 1. (2146 aa) |
| | POLR1A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1720 aa) |
| | SNAPC2 | Small nuclear RNA activating complex polypeptide 2. (366 aa) |
| | CRCP | CGRP receptor component. (148 aa) |
| | MED26 | TFIIS N-terminal domain-containing protein. (599 aa) |
| | CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa) |
| | BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB. (2567 aa) |
| | GTF2A2 | General transcription factor IIA subunit 2. (140 aa) |
| | AFF4 | AF4/FMR2 family member 4. (1164 aa) |
| | NELFE | Negative elongation factor complex member E. (442 aa) |
| | ELOF1 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (90 aa) |
| | GTF2A1L | Uncharacterized protein. (473 aa) |
| | PLPPR2 | Phospholipid phosphatase related 2. (343 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | MED19 | Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa) |
| | GTF3C6 | General transcription factor IIIC subunit 6. (226 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (469 aa) |
| | TWISTNB | TWIST neighbor. (339 aa) |
| | POLR1E | RNA polymerase I subunit E. (419 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | CDK8 | Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa) |
| | POLR2C | RNA polymerase II subunit C. (275 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (395 aa) |
| | C7H11orf88 | Chromosome 7 C11orf88 homolog. (168 aa) |
| | ZNRD1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa) |
| | SNAPC4 | Small nuclear RNA activating complex polypeptide 4. (1461 aa) |
| | CCNT1 | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNAP II) (By similarity). In case of equine infectious anemia virus (EIAV) infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Ta [...] (751 aa) |
| | POLR3E | RNA polymerase III subunit E. (797 aa) |
| | LOC100060825 | Uncharacterized protein. (253 aa) |
| | SUPT4H1 | Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa) |
| | NELFCD | Negative elongation factor complex member C/D. (597 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (211 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (869 aa) |
| | MED15 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (782 aa) |
| | CDK13 | Cyclin dependent kinase 13. (1515 aa) |
| | MED28 | Mediator complex subunit 28. (178 aa) |
| | SNAPC1 | Small nuclear RNA activating complex polypeptide 1. (369 aa) |
| | C20H6orf15 | Chromosome 20 C6orf15 homolog. (312 aa) |
| | GTF2E2 | General transcription factor IIE subunit 2. (337 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2172 aa) |
| | MED29 | Mediator complex subunit 29. (220 aa) |
| | BRF1 | BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (582 aa) |
| | POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa) |
| | POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa) |
| | MED20 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa) |
| | TCEA2 | Transcription elongation factor A2. (299 aa) |
| | POLR2K | RNA polymerase II subunit K. (58 aa) |
| | POLR2G | RNA polymerase II subunit G. (172 aa) |
| | CDK12 | Cyclin dependent kinase 12. (1427 aa) |
| | CTDP1 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (957 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | MED30 | Mediator complex subunit 30. (178 aa) |
| | MED27 | Mediator complex subunit 27. (354 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (916 aa) |
| | ELL2 | Elongation factor for RNA polymerase II 2. (657 aa) |
| | MED21 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa) |
| | LOC100068123 | Uncharacterized protein. (531 aa) |
| | POLR1C | RNA polymerase I and III subunit C. (346 aa) |
| | CCDC17 | Coiled-coil domain containing 17. (622 aa) |
| | MED13L | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2210 aa) |
| | MED10 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (135 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | ICE1 | Interactor of little elongation complex ELL subunit 1. (2271 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa) |
| | EAF1 | ELL associated factor 1. (357 aa) |
| | CCNC | Cyclin C; Belongs to the cyclin family. (283 aa) |
| | POLR3G | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa) |
| | GTF2B | Transcription initiation factor IIB-like protein. (316 aa) |
| | POLR3K | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) |
| | MED31 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa) |
| | POLR3D | Uncharacterized protein. (398 aa) |
| | LOC100056183 | ELL domain-containing protein. (537 aa) |
| | MED12 | Mediator complex subunit 12. (2099 aa) |
| | MED9 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (147 aa) |
| | GTF3C4 | General transcription factor IIIC subunit 4. (821 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (261 aa) |
| | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa) |
| | ENSECAP00000028527 | Uncharacterized protein. (118 aa) |
| | POLR3H | RNA polymerase III subunit H. (204 aa) |
| | ICE2 | Interactor of little elongation complex ELL subunit 2. (1026 aa) |
| | POLR1A-2 | RNA polymerase I subunit A. (1720 aa) |
| | GTF2H4 | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (769 aa) |
| | TAF8 | TATA-box binding protein associated factor 8. (310 aa) |
| | TCEA3 | Transcription elongation factor A3. (433 aa) |
| | LOC111771996 | DNA-directed RNA polymerase I subunit RPA1. (1720 aa) |
| | TCEA1 | Transcription elongation factor A1. (328 aa) |
| | ENSECAP00000031809 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) |
| | ELL | Elongation factor for RNA polymerase II. (729 aa) |
| | TBPL1 | TATA-box binding protein like 1. (217 aa) |
| | MED23 | Mediator complex subunit 23. (1497 aa) |
| | NELFB | Negative elongation factor complex member B. (627 aa) |
| | SIDT1 | SID1 transmembrane family member 1. (824 aa) |
| | CDK7 | Cyclin dependent kinase 7. (380 aa) |
| | ENSECAP00000034956 | Uncharacterized protein. (201 aa) |
| | MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (253 aa) |
| | SUPT5H | Transcription elongation factor SPT5. (1087 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (609 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (494 aa) |
| | SUPT6H | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1729 aa) |
| | ENSECAP00000037495 | Uncharacterized protein. (395 aa) |
| | LEO1 | LEO1 homolog, Paf1/RNA polymerase II complex component. (691 aa) |
| | GTF2H1 | General transcription factor IIH subunit 1. (594 aa) |
| | TAF13 | TATA-box binding protein associated factor 13. (164 aa) |
| | POLR2E | RNA polymerase II subunit E. (210 aa) |
| | NELFA | Negative elongation factor complex member A. (546 aa) |
| | SP1 | Sp1 transcription factor. (787 aa) |
| | PLPPR5 | Phospholipid phosphatase related 5. (379 aa) |
| | ELOA-2 | Uncharacterized protein. (763 aa) |
| | MLLT1 | MLLT1 super elongation complex subunit. (745 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (928 aa) |
| | MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (653 aa) |
| | ENSECAP00000041128 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (117 aa) |
| | GTF2E1 | General transcription factor IIE subunit 1. (524 aa) |
| | AFF1 | AF4/FMR2 family member 1. (1236 aa) |
| | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (582 aa) |
| | GTF3C2 | General transcription factor IIIC subunit 2; Belongs to the eIF-2B alpha/beta/delta subunits family. (1443 aa) |
| | MED12L | Mediator complex subunit 12L. (2158 aa) |
| | GTF2H5 | General transcription factor IIH subunit 5. (71 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (322 aa) |
| | GTF3C3 | General transcription factor IIIC subunit 3. (904 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (733 aa) |
| | POLR2J | RNA polymerase II subunit J. (117 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (730 aa) |
| | POLR2L | RNA polymerase II subunit L. (67 aa) |
| | ENSECAP00000046013 | Uncharacterized protein. (79 aa) |
| | EAF2 | ELL associated factor 2. (296 aa) |
| | POLR3GL | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (218 aa) |
| | ENSECAP00000046585 | Uncharacterized protein. (761 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1260 aa) |
| | ENSECAP00000047995 | Uncharacterized protein. (688 aa) |
| | CINP | Cyclin dependent kinase 2 interacting protein. (223 aa) |
| | MED11 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (949 aa) |
| | POLR3A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1359 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (306 aa) |
| | CD3EAP | CD3e molecule associated protein. (542 aa) |
| | MED24 | Mediator complex subunit 24. (1008 aa) |
| | ADA2 | Haloacid dehalogenase like hydrolase domain containing 5. (633 aa) |
| | PRR30 | Uncharacterized protein. (303 aa) |
| | IWS1 | Interacts with SUPT6H, CTD assembly factor 1. (942 aa) |
| | RUNX1T1 | RUNX1 partner transcriptional co-repressor 1. (662 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1491 aa) |
| | GTF2H3 | General transcription factor IIH subunit 3. (309 aa) |
| | SSRP1 | HMG box domain-containing protein. (2401 aa) |
