(21 nodes) RNA polymerase II, core complex, and Cdc73/Paf1 complex network (Equus caballus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POLR2D	RNA polymerase II subunit D. (142 aa)
	POLR2L-2	RNA polymerase II subunit L. (79 aa)
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	CTR9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
	POLR2I	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	CDC73	Cell division cycle 73. (531 aa)
	POLR2C	RNA polymerase II subunit C. (275 aa)
	SUPT4H1	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
	POLR2K	RNA polymerase II subunit K. (58 aa)
	POLR2G	RNA polymerase II subunit G. (172 aa)
	SUPT16H	SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
	SUPT5H	Transcription elongation factor SPT5. (1087 aa)
	LEO1	LEO1 homolog, Paf1/RNA polymerase II complex component. (691 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	PAF1	PAF1 homolog, Paf1/RNA polymerase II complex component. (582 aa)
	POLR2J	RNA polymerase II subunit J. (117 aa)
	RTF1	RTF1 homolog, Paf1/RNA polymerase II complex component. (730 aa)
	POLR2L	RNA polymerase II subunit L. (67 aa)
	SSRP1	HMG box domain-containing protein. (2401 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	CTR9	ENSECAP00000013089	ENSECAP00000009320	Cell division cycle 73.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	LEO1	ENSECAP00000013089	ENSECAP00000037848	Cell division cycle 73.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	PAF1	ENSECAP00000013089	ENSECAP00000042177	Cell division cycle 73.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	POLR2A	ENSECAP00000013089	ENSECAP00000016572	Cell division cycle 73.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.969
CDC73	POLR2B	ENSECAP00000013089	ENSECAP00000011680	Cell division cycle 73.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.949
CDC73	POLR2C	ENSECAP00000013089	ENSECAP00000013423	Cell division cycle 73.	RNA polymerase II subunit C.	0.889
CDC73	POLR2D	ENSECAP00000013089	ENSECAP00000000343	Cell division cycle 73.	RNA polymerase II subunit D.	0.824
CDC73	POLR2E	ENSECAP00000013089	ENSECAP00000038558	Cell division cycle 73.	RNA polymerase II subunit E.	0.876
CDC73	POLR2G	ENSECAP00000013089	ENSECAP00000018880	Cell division cycle 73.	RNA polymerase II subunit G.	0.866
CDC73	POLR2H	ENSECAP00000013089	ENSECAP00000004070	Cell division cycle 73.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.899
CDC73	POLR2I	ENSECAP00000013089	ENSECAP00000011342	Cell division cycle 73.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.846
CDC73	POLR2J	ENSECAP00000013089	ENSECAP00000044822	Cell division cycle 73.	RNA polymerase II subunit J.	0.855
CDC73	POLR2K	ENSECAP00000013089	ENSECAP00000018798	Cell division cycle 73.	RNA polymerase II subunit K.	0.633
CDC73	POLR2L	ENSECAP00000013089	ENSECAP00000045199	Cell division cycle 73.	RNA polymerase II subunit L.	0.700
CDC73	POLR2L-2	ENSECAP00000013089	ENSECAP00000000800	Cell division cycle 73.	RNA polymerase II subunit L.	0.700
CDC73	RTF1	ENSECAP00000013089	ENSECAP00000044835	Cell division cycle 73.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	SSRP1	ENSECAP00000013089	ENSECAP00000054742	Cell division cycle 73.	HMG box domain-containing protein.	0.994
CDC73	SUPT16H	ENSECAP00000013089	ENSECAP00000019387	Cell division cycle 73.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.994
CDC73	SUPT4H1	ENSECAP00000013089	ENSECAP00000014226	Cell division cycle 73.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.949
CDC73	SUPT5H	ENSECAP00000013089	ENSECAP00000035331	Cell division cycle 73.	Transcription elongation factor SPT5.	0.981