(19 nodes) BLOC complex, and BORC complex network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BORCS6	BLOC-1 related complex subunit 6. (354 aa)
	HPS1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (735 aa)
	BLOC1S4	Biogenesis of lysosomal organelles complex 1 subunit 4. (215 aa)
	HPS6	Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (803 aa)
	BORCS7	Uncharacterized protein. (106 aa)
	BORCS8	Uncharacterized protein. (119 aa)
	HPS3	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation. (1003 aa)
	BLOC1S5	Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (188 aa)
	BLOC1S2	Biogenesis of lysosomal organelles complex 1 subunit 2. (156 aa)
	HPS4	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (697 aa)
	SNAPIN	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
	BLOC1S1	Uncharacterized protein. (75 aa)
	BORCS5	BLOC-1 related complex subunit 5. (298 aa)
	PCMT1	Protein-L-isoaspartate O-methyltransferase. (307 aa)
	ENSECAP00000032857	Uncharacterized protein. (46 aa)
	LOC100060806	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
	DTNBP1	Dystrobrevin binding protein 1. (403 aa)
	HPS5	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1129 aa)
	KXD1	KxDL motif containing 1. (194 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLOC1S1	BLOC1S2	ENSECAP00000023308	ENSECAP00000011178	Uncharacterized protein.	Biogenesis of lysosomal organelles complex 1 subunit 2.	0.930
BLOC1S1	BLOC1S4	ENSECAP00000023308	ENSECAP00000002651	Uncharacterized protein.	Biogenesis of lysosomal organelles complex 1 subunit 4.	0.978
BLOC1S1	BLOC1S5	ENSECAP00000023308	ENSECAP00000008495	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).	0.866
BLOC1S1	BORCS5	ENSECAP00000023308	ENSECAP00000026600	Uncharacterized protein.	BLOC-1 related complex subunit 5.	0.587
BLOC1S1	BORCS6	ENSECAP00000023308	ENSECAP00000002111	Uncharacterized protein.	BLOC-1 related complex subunit 6.	0.593
BLOC1S1	BORCS7	ENSECAP00000023308	ENSECAP00000005281	Uncharacterized protein.	Uncharacterized protein.	0.579
BLOC1S1	BORCS8	ENSECAP00000023308	ENSECAP00000005601	Uncharacterized protein.	Uncharacterized protein.	0.624
BLOC1S1	DTNBP1	ENSECAP00000023308	ENSECAP00000040643	Uncharacterized protein.	Dystrobrevin binding protein 1.	0.985
BLOC1S1	ENSECAP00000032857	ENSECAP00000023308	ENSECAP00000032857	Uncharacterized protein.	Uncharacterized protein.	0.939
BLOC1S1	HPS1	ENSECAP00000023308	ENSECAP00000002472	Uncharacterized protein.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.449
BLOC1S1	HPS3	ENSECAP00000023308	ENSECAP00000006572	Uncharacterized protein.	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	0.529
BLOC1S1	HPS5	ENSECAP00000023308	ENSECAP00000046065	Uncharacterized protein.	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.512
BLOC1S1	HPS6	ENSECAP00000023308	ENSECAP00000003116	Uncharacterized protein.	Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.481
BLOC1S1	KXD1	ENSECAP00000023308	ENSECAP00000049049	Uncharacterized protein.	KxDL motif containing 1.	0.537
BLOC1S1	LOC100060806	ENSECAP00000023308	ENSECAP00000038836	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.959
BLOC1S1	SNAPIN	ENSECAP00000023308	ENSECAP00000017898	Uncharacterized protein.	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]	0.913
BLOC1S2	BLOC1S1	ENSECAP00000011178	ENSECAP00000023308	Biogenesis of lysosomal organelles complex 1 subunit 2.	Uncharacterized protein.	0.930
BLOC1S2	BLOC1S4	ENSECAP00000011178	ENSECAP00000002651	Biogenesis of lysosomal organelles complex 1 subunit 2.	Biogenesis of lysosomal organelles complex 1 subunit 4.	0.727
BLOC1S2	BLOC1S5	ENSECAP00000011178	ENSECAP00000008495	Biogenesis of lysosomal organelles complex 1 subunit 2.	Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).	0.889
BLOC1S2	BORCS5	ENSECAP00000011178	ENSECAP00000026600	Biogenesis of lysosomal organelles complex 1 subunit 2.	BLOC-1 related complex subunit 5.	0.742