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TYROBP | TYRO protein tyrosine kinase binding protein. (144 aa) | ||||
IL18RAP | Interleukin 18 receptor accessory protein. (600 aa) | ||||
TRAF3IP2 | TRAF3 interacting protein 2. (578 aa) | ||||
IFI35 | Interferon induced protein 35. (280 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
F2RL1 | F2R like trypsin receptor 1. (397 aa) | ||||
PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) | ||||
CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa) | ||||
C5AR1 | Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (374 aa) | ||||
MILR1 | Mast cell immunoglobulin like receptor 1. (348 aa) | ||||
ADAM9 | ADAM metallopeptidase domain 9. (819 aa) | ||||
PTGDR | Prostaglandin D2 receptor. (293 aa) | ||||
ADAM10 | ADAM metallopeptidase domain 10. (748 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (139 aa) | ||||
DNASE1 | Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (By similarity). Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation. Degradation of intra [...] (282 aa) | ||||
SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa) | ||||
FCER1G | Fc fragment of IgE receptor Ig. (86 aa) | ||||
CSF2 | Granulocyte-macrophage colony-stimulating factor. (152 aa) | ||||
IL13 | Interleukin-13. (133 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (843 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (797 aa) | ||||
BATF3 | Basic leucine zipper ATF-like transcription factor 3. (253 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) | ||||
ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (918 aa) | ||||
KIT | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule family member 1. (338 aa) | ||||
CPLX2 | Complexin 2. (134 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (298 aa) | ||||
HAVCR2 | Hepatitis A virus cellular receptor 2. (280 aa) | ||||
CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity). (101 aa) | ||||
BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) | ||||
ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa) | ||||
PLA2G10 | Phospholipase A(2). (160 aa) | ||||
CAMK4 | Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa) | ||||
L3HYPDH | Trans-L-3-hydroxyproline dehydratase. (354 aa) | ||||
RABGEF1 | RAB guanine nucleotide exchange factor 1. (492 aa) | ||||
ANXA3 | Annexin. (323 aa) | ||||
DCSTAMP | Dendrocyte expressed seven transmembrane protein. (470 aa) | ||||
ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (767 aa) | ||||
GRP | Gastrin releasing peptide. (138 aa) | ||||
RELB | RELB proto-oncogene, NF-kB subunit. (709 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (403 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa) | ||||
JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa) | ||||
STARD7 | StAR related lipid transfer domain containing 7. (375 aa) | ||||
STXBP3 | Pre-mRNA processing factor 38B; Belongs to the STXBP/unc-18/SEC1 family. (1126 aa) | ||||
LCP2 | Lymphocyte cytosolic protein 2. (533 aa) | ||||
APP | Amyloid beta precursor protein. (811 aa) | ||||
S100A13 | S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (340 aa) | ||||
DNASE1L2 | Deoxyribonuclease; Belongs to the DNase I family. (278 aa) | ||||
SUCNR1 | Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa) | ||||
CRTC3 | CREB regulated transcription coactivator 3. (619 aa) | ||||
PLA2G3 | Phospholipase A2 group III. (513 aa) | ||||
DOCK2 | Dedicator of cytokinesis 2; Belongs to the DOCK family. (1828 aa) | ||||
STK39 | Serine/threonine kinase 39. (556 aa) | ||||
DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (311 aa) | ||||
DYSF | Dysferlin. (2121 aa) | ||||
CLNK | Cytokine dependent hematopoietic cell linker. (429 aa) | ||||
ENSECAP00000024650 | Uncharacterized protein. (88 aa) | ||||
IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (432 aa) | ||||
IRF4 | Interferon regulatory factor 4. (606 aa) | ||||
NDRG1 | N-myc downstream regulated 1. (384 aa) | ||||
CD99 | CD99 molecule (Xg blood group). (209 aa) | ||||
KMT2E | Lysine methyltransferase 2E. (1857 aa) | ||||
CHGA | p-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Serpinin]: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation. (458 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
TMEM106A | Transmembrane protein 106A. (261 aa) | ||||
LOC100051526 | Uncharacterized protein. (285 aa) | ||||
PLCG2 | Phosphoinositide phospholipase C. (1331 aa) | ||||
FOXP1 | Forkhead box P1. (691 aa) | ||||
ENSECAP00000033220 | AIG1-type G domain-containing protein. (267 aa) | ||||
LOC111771935 | Toll-like receptor 4. (843 aa) | ||||
VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (276 aa) | ||||
RHOH | Ras homolog family member H. (191 aa) | ||||
LOC100146250 | AIG1-type G domain-containing protein. (315 aa) | ||||
SLC11A1 | Solute carrier family 11 member 1. (648 aa) | ||||
ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa) | ||||
SYK | Tyrosine-protein kinase. (716 aa) | ||||
LTBR | Lymphotoxin beta receptor. (434 aa) | ||||
BCR | BCR activator of RhoGEF and GTPase. (1325 aa) | ||||
NMI | N-myc and STAT interactor. (309 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
AZU1 | Azurocidin 1. (251 aa) | ||||
SBNO2 | Strawberry notch homolog 2. (1370 aa) | ||||
BATF2 | Basic leucine zipper ATF-like transcription factor 2. (272 aa) | ||||
LOC100630393 | AIG1-type G domain-containing protein. (315 aa) | ||||
RAB44 | RAB44, member RAS oncogene family. (1012 aa) | ||||
LOC100063866 | AIG1-type G domain-containing protein. (413 aa) | ||||
NOTCH2 | Notch receptor 2. (2471 aa) | ||||
CCL3 | SCY domain-containing protein. (226 aa) | ||||
TREX1 | Three prime repair exonuclease 1. (314 aa) | ||||
KARS1 | Lysine--tRNA ligase. (625 aa) | ||||
VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (118 aa) | ||||
CHGA-2 | Chromogranin A. (458 aa) | ||||
PTGDS | Prostaglandin-H2 D-isomerase; Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possib [...] (200 aa) | ||||
WNK4 | WNK lysine deficient protein kinase 4. (1246 aa) |