(16 nodes) Outflow tract septum morphogenesis network (Equus caballus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	TBX20	T-box transcription factor 20. (449 aa)
	NRP2	Neuropilin 2. (976 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	ZFPM2	Zinc finger protein, FOG family member 2. (1150 aa)
	TBX2	T-box transcription factor 2. (755 aa)
	GATA6	GATA binding protein 6. (598 aa)
	LRP2	LDL receptor related protein 2. (4673 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SMAD6	Mothers against decapentaplegic homolog. (498 aa)
	PARVA	Parvin alpha. (459 aa)
	AK1	Endoglin. (848 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
	NKX2-5	NK2 homeobox 5. (322 aa)
	SEMA3C	Semaphorin 3C; Belongs to the semaphorin family. (751 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK1	BMPR2	ENSECAP00000033996	ENSECAP00000022713	Endoglin.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.632
BMP4	BMPR1A	ENSECAP00000015252	ENSECAP00000018155	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP4	BMPR2	ENSECAP00000015252	ENSECAP00000022713	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.993
BMP4	FGF8	ENSECAP00000015252	ENSECAP00000052303	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.698
BMP4	GATA6	ENSECAP00000015252	ENSECAP00000042692	Bone morphogenetic protein 4.	GATA binding protein 6.	0.678
BMP4	NKX2-5	ENSECAP00000015252	ENSECAP00000020947	Bone morphogenetic protein 4.	NK2 homeobox 5.	0.463
BMP4	SMAD4	ENSECAP00000015252	ENSECAP00000025183	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.906
BMP4	SMAD6	ENSECAP00000015252	ENSECAP00000011390	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.769
BMP4	TBX2	ENSECAP00000015252	ENSECAP00000022090	Bone morphogenetic protein 4.	T-box transcription factor 2.	0.411
BMPR1A	BMP4	ENSECAP00000018155	ENSECAP00000015252	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.996
BMPR1A	BMPR2	ENSECAP00000018155	ENSECAP00000022713	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.983
BMPR1A	SMAD4	ENSECAP00000018155	ENSECAP00000025183	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.849
BMPR1A	SMAD6	ENSECAP00000018155	ENSECAP00000011390	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.818
BMPR2	AK1	ENSECAP00000022713	ENSECAP00000033996	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Endoglin.	0.632
BMPR2	BMP4	ENSECAP00000022713	ENSECAP00000015252	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.993
BMPR2	BMPR1A	ENSECAP00000022713	ENSECAP00000018155	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.983
BMPR2	SMAD4	ENSECAP00000022713	ENSECAP00000025183	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.848
BMPR2	SMAD6	ENSECAP00000022713	ENSECAP00000011390	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.753
FGF8	BMP4	ENSECAP00000052303	ENSECAP00000015252	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.698
GATA6	BMP4	ENSECAP00000042692	ENSECAP00000015252	GATA binding protein 6.	Bone morphogenetic protein 4.	0.678