STRINGSTRING
ADGRA2 ADGRA2 TESK1 TESK1 KITLG KITLG FERMT1 FERMT1 S100Z S100Z GREM1 GREM1 NANOS1 NANOS1 CLEC14A CLEC14A S100A2 S100A2 PPARD PPARD SRF SRF VEGFA VEGFA SNAI1 SNAI1 GIPC2 GIPC2 EPHB4 EPHB4 CXCL13 CXCL13 EFNB2 EFNB2 KIT KIT FGF2 FGF2 CORO1B CORO1B MMRN2 MMRN2 PAXIP1 PAXIP1 CDH5 CDH5 PROX1 PROX1 CYP1B1 CYP1B1 KDR KDR ROCK1 ROCK1 MYH9 MYH9 CCN3 CCN3 VSTM4 VSTM4 ARSJ ARSJ SCARB1 SCARB1 PTPN11 PTPN11 NOS3 NOS3 CORO1A CORO1A PKN2 PKN2 LOXL2 LOXL2 ENSECAP00000023776 ENSECAP00000023776 FAT2 FAT2 PKN1 PKN1 WDPCP WDPCP LGALS8 LGALS8 RAB13 RAB13 PLXND1 PLXND1 KANK2 KANK2 LOC100052122 LOC100052122 ABL1 ABL1 ENSECAP00000032767 ENSECAP00000032767 SOX18 SOX18 PRKX PRKX DPP4 DPP4 NRP1 NRP1 ARSB ARSB PTP4A3 PTP4A3 LTB4R2 LTB4R2 AMOT AMOT CCBE1 CCBE1 GPLD1 GPLD1 STARD13 STARD13 GIPC3 GIPC3 LRG1 LRG1 SLIT2 SLIT2 KANK1 KANK1 PXN PXN EMP2 EMP2 LGALS12 LGALS12 GIPC1 GIPC1 ANLN ANLN CDH13 CDH13 ENSECAP00000044898 ENSECAP00000044898 ADTRP ADTRP TGFBR1 TGFBR1 PKN3 PKN3 ITGB1 ITGB1 EGR3 EGR3 LPXN LPXN PLEKHG5 PLEKHG5 FSTL1 FSTL1 ARSI ARSI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1338 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
KITLGProcessed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (303 aa)
FERMT1Fermitin family member 1. (677 aa)
S100ZProtein S100; Belongs to the S-100 family. (102 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (143 aa)
NANOS1Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (289 aa)
CLEC14AC-type lectin domain containing 14A. (500 aa)
S100A2S100 calcium binding protein A2. (223 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
SRFSerum response factor. (512 aa)
VEGFAVascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (448 aa)
SNAI1Snail family transcriptional repressor 1. (265 aa)
GIPC2GIPC PDZ domain containing family member 2. (314 aa)
EPHB4EPH receptor B4. (987 aa)
CXCL13C-X-C motif chemokine. (110 aa)
EFNB2Ephrin-B2; Belongs to the ephrin family. (333 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
MMRN2Multimerin 2. (916 aa)
PAXIP1PAX interacting protein 1. (1116 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (850 aa)
PROX1Prospero homeobox 1. (737 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (560 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1358 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
CCN3Cellular communication network factor 3. (358 aa)
VSTM4V-set and transmembrane domain containing 4. (319 aa)
ARSJArylsulfatase family member J. (598 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (606 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1267 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
PKN2Protein kinase N2. (983 aa)
LOXL2Lysyl oxidase like 2. (1047 aa)
ENSECAP00000023776TYR_PHOSPHATASE_2 domain-containing protein. (161 aa)
FAT2FAT atypical cadherin 2. (4351 aa)
PKN1Protein kinase N1. (1098 aa)
WDPCPWD repeat containing planar cell polarity effector. (714 aa)
LGALS8Galectin. (357 aa)
RAB13RAB13, member RAS oncogene family. (273 aa)
PLXND1Plexin D1. (2046 aa)
KANK2KN motif and ankyrin repeat domains 2. (947 aa)
LOC100052122Uncharacterized protein. (461 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ENSECAP00000032767annotation not available (133 aa)
SOX18SRY-box transcription factor 18. (383 aa)
PRKXProtein kinase X-linked; Belongs to the protein kinase superfamily. (356 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (869 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ARSBArylsulfatase B. (525 aa)
PTP4A3TYR_PHOSPHATASE_2 domain-containing protein. (366 aa)
LTB4R2Leukotriene B4 receptor 2. (369 aa)
AMOTAngiomotin. (1089 aa)
CCBE1Collagen and calcium binding EGF domains 1. (439 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (867 aa)
STARD13StAR related lipid transfer domain containing 13. (1144 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
KANK1KN motif and ankyrin repeat domains 1. (1433 aa)
PXNPaxillin. (1236 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (205 aa)
LGALS12Galectin. (325 aa)
GIPC1GIPC PDZ domain containing family member 1. (332 aa)
ANLNAnillin actin binding protein. (1172 aa)
CDH13Cadherin 13. (712 aa)
ENSECAP00000044898annotation not available (133 aa)
ADTRPAndrogen dependent TFPI regulating protein. (234 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
PKN3Protein kinase N3. (908 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (808 aa)
EGR3Early growth response 3. (387 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1080 aa)
FSTL1Follistatin like 1. (317 aa)
ARSIArylsulfatase family member I. (574 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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