(14 nodes) Fibroblast migration network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ILK	Integrin linked kinase. (452 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (307 aa)
	LAMTOR2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (150 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (2101 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (610 aa)
	SCHIP1	SCHIP-1 domain-containing protein. (500 aa)
	TNS1	Tensin 1. (2082 aa)
	CD248	CD248 molecule. (773 aa)
	PIP5K1A	PIPK domain-containing protein. (565 aa)
	TMEM201	Transmembrane protein 201. (689 aa)
	ZFAND5	Zinc finger AN1-type containing 5. (216 aa)
	CCN3	Cellular communication network factor 3. (358 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (365 aa)
	PML	Promyelocytic leukemia. (881 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ILK	TNS1	ENSECAP00000029258	ENSECAP00000033469	Integrin linked kinase.	Tensin 1.	0.454
IQGAP1	LAMTOR2	ENSECAP00000039842	ENSECAP00000049327	IQ motif containing GTPase activating protein 1.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.472
LAMTOR2	IQGAP1	ENSECAP00000049327	ENSECAP00000039842	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	IQ motif containing GTPase activating protein 1.	0.472
PIP5K1A	SCHIP1	ENSECAP00000030179	ENSECAP00000034236	PIPK domain-containing protein.	SCHIP-1 domain-containing protein.	0.409
SCHIP1	PIP5K1A	ENSECAP00000034236	ENSECAP00000030179	SCHIP-1 domain-containing protein.	PIPK domain-containing protein.	0.409
SCHIP1	ZFAND5	ENSECAP00000034236	ENSECAP00000021229	SCHIP-1 domain-containing protein.	Zinc finger AN1-type containing 5.	0.817
TNS1	ILK	ENSECAP00000033469	ENSECAP00000029258	Tensin 1.	Integrin linked kinase.	0.454
ZFAND5	SCHIP1	ENSECAP00000021229	ENSECAP00000034236	Zinc finger AN1-type containing 5.	SCHIP-1 domain-containing protein.	0.817