(16 nodes) Negative regulation of lipid storage network (Equus caballus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (388 aa)
	ITGAV	Family with sequence similarity 171 member B; Belongs to the integrin alpha chain family. (1787 aa)
	ABHD5	Abhydrolase domain containing 5. (378 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (492 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (491 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (298 aa)
	TTC39A	Tetratricopeptide repeat domain 39A. (581 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (447 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	NFKBIA	NFKB inhibitor alpha. (543 aa)
	TTC39B	Tetratricopeptide repeat domain 39B. (706 aa)
	ENSECAP00000036553	Uncharacterized protein. (46 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (927 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	LOC100069973	Uncharacterized protein. (589 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD5	PNPLA2	ENSECAP00000040210	ENSECAP00000010153	Abhydrolase domain containing 5.	Patatin like phospholipase domain containing 2.	0.972
ENSECAP00000036553	PNPLA2	ENSECAP00000036553	ENSECAP00000010153	Uncharacterized protein.	Patatin like phospholipase domain containing 2.	0.629
ITGAV	ITGB3	ENSECAP00000042187	ENSECAP00000016485	Family with sequence similarity 171 member B; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGB3	ITGAV	ENSECAP00000016485	ENSECAP00000042187	Integrin beta; Belongs to the integrin beta chain family.	Family with sequence similarity 171 member B; Belongs to the integrin alpha chain family.	0.999
NR1H2	NR1H3	ENSECAP00000037451	ENSECAP00000013323	Nuclear receptor subfamily 1 group H member 2.	Nuclear receptor subfamily 1 group H member 3.	0.447
NR1H2	PPARA	ENSECAP00000037451	ENSECAP00000035243	Nuclear receptor subfamily 1 group H member 2.	Peroxisome proliferator activated receptor alpha.	0.449
NR1H3	NR1H2	ENSECAP00000013323	ENSECAP00000037451	Nuclear receptor subfamily 1 group H member 3.	Nuclear receptor subfamily 1 group H member 2.	0.447
NR1H3	PPARA	ENSECAP00000013323	ENSECAP00000035243	Nuclear receptor subfamily 1 group H member 3.	Peroxisome proliferator activated receptor alpha.	0.503
PNPLA2	ABHD5	ENSECAP00000010153	ENSECAP00000040210	Patatin like phospholipase domain containing 2.	Abhydrolase domain containing 5.	0.972
PNPLA2	ENSECAP00000036553	ENSECAP00000010153	ENSECAP00000036553	Patatin like phospholipase domain containing 2.	Uncharacterized protein.	0.629
PNPLA2	PPARA	ENSECAP00000010153	ENSECAP00000035243	Patatin like phospholipase domain containing 2.	Peroxisome proliferator activated receptor alpha.	0.470
PPARA	NR1H2	ENSECAP00000035243	ENSECAP00000037451	Peroxisome proliferator activated receptor alpha.	Nuclear receptor subfamily 1 group H member 2.	0.449
PPARA	NR1H3	ENSECAP00000035243	ENSECAP00000013323	Peroxisome proliferator activated receptor alpha.	Nuclear receptor subfamily 1 group H member 3.	0.503
PPARA	PNPLA2	ENSECAP00000035243	ENSECAP00000010153	Peroxisome proliferator activated receptor alpha.	Patatin like phospholipase domain containing 2.	0.470
PPARA	PPARD	ENSECAP00000035243	ENSECAP00000006517	Peroxisome proliferator activated receptor alpha.	Peroxisome proliferator activated receptor delta.	0.438
PPARD	PPARA	ENSECAP00000006517	ENSECAP00000035243	Peroxisome proliferator activated receptor delta.	Peroxisome proliferator activated receptor alpha.	0.438