STRINGSTRING
SLC66A3 SLC66A3 GOT1 GOT1 G6PC G6PC GLT8D1 GLT8D1 B3GNT4 B3GNT4 HS2ST1 HS2ST1 NHLRC1 NHLRC1 LALBA LALBA PHKG2 PHKG2 LOC100060483 LOC100060483 EPM2AIP1 EPM2AIP1 MGAT2 MGAT2 SORD SORD MPDU1 MPDU1 B3GNT9 B3GNT9 NR1D1 NR1D1 B3GNT7 B3GNT7 PHKG1 PHKG1 ATF4 ATF4 SLC39A14 SLC39A14 PGP PGP ST6GALNAC1 ST6GALNAC1 ATF3 ATF3 AGL AGL ST6GALNAC6 ST6GALNAC6 ALDOC ALDOC PPP1R3C PPP1R3C PCK1 PCK1 LEPR LEPR FUT9 FUT9 GBE1 GBE1 GYS2 GYS2 G6PD G6PD PGK1 PGK1 CRY1 CRY1 TPI1 TPI1 B3GNT3 B3GNT3 B3GNT2 B3GNT2 CHST10 CHST10 NDST2 NDST2 GPI GPI B3GNT6 B3GNT6 ISYNA1 ISYNA1 HAS2 HAS2 CHST15 CHST15 B4GALT5 B4GALT5 NDST3 NDST3 IMPA1 IMPA1 GYG1 GYG1 EXT1 EXT1 ST3GAL2 ST3GAL2 G6PC3 G6PC3 SERPINA12 SERPINA12 B3GNT8 B3GNT8 KAT2A KAT2A PCK2 PCK2 SLC37A4 SLC37A4 G6PC2 G6PC2 ENSECAP00000028904 ENSECAP00000028904 IMPA2 IMPA2 LOC102148379 LOC102148379 NANS NANS KAT2B KAT2B B4GALT1 B4GALT1 WDR5 WDR5 PPARGC1A PPARGC1A ACADM ACADM PRKAG3 PRKAG3 GLT8D2 GLT8D2 NDST4 NDST4 CHST8 CHST8 GPD1 GPD1 PGK2 PGK2 ENSECAP00000039423 ENSECAP00000039423 RGN RGN CHST11 CHST11 CHST13 CHST13 GYS1 GYS1 CHST9 CHST9 HAS3 HAS3 HAS1 HAS1 GYG2 GYG2 C1QTNF12 C1QTNF12 FBP1 FBP1 UGP2 UGP2 NDST1 NDST1 PC PC SDS SDS EXT2 EXT2 ST3GAL4 ST3GAL4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC66A3Solute carrier family 66 member 3. (286 aa)
GOT1Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (423 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
GLT8D1Glycosyltransferase 8 domain containing 1. (401 aa)
B3GNT4Hexosyltransferase. (354 aa)
HS2ST1Uncharacterized protein. (356 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (487 aa)
LALBAAlpha-lactalbumin A; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. (148 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
LOC100060483FAD-binding PCMH-type domain-containing protein. (440 aa)
EPM2AIP1EPM2A interacting protein 1. (608 aa)
MGAT2Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (441 aa)
SORDSorbitol dehydrogenase. (356 aa)
MPDU1Mannose-P-dolichol utilization defect 1. (246 aa)
B3GNT9Hexosyltransferase. (402 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (605 aa)
B3GNT7Hexosyltransferase. (401 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (387 aa)
ATF4Activating transcription factor 4. (334 aa)
SLC39A14Solute carrier family 39 member 14. (532 aa)
PGPPhosphoglycolate phosphatase. (347 aa)
ST6GALNAC1ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (598 aa)
ATF3Activating transcription factor 3. (251 aa)
AGLAmylo-alpha-1,6-glucosidase; Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation; Belongs to the glycogen debranching enzyme family. (1533 aa)
ST6GALNAC6ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (333 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (342 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
LEPRLeptin receptor. (1165 aa)
FUT9Fucosyltransferase 9. (382 aa)
GBE11,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (699 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (637 aa)
PGK1Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. (417 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
TPI1Triosephosphate isomerase. (286 aa)
B3GNT3Hexosyltransferase. (372 aa)
B3GNT2Hexosyltransferase. (397 aa)
CHST10Carbohydrate sulfotransferase. (381 aa)
NDST2N-deacetylase and N-sulfotransferase 2. (884 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa)
B3GNT6Hexosyltransferase. (410 aa)
ISYNA1Inositol-3-phosphate synthase 1. (557 aa)
HAS2Hyaluronan synthase 2. (552 aa)
CHST15Carbohydrate sulfotransferase 15. (561 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
NDST3N-deacetylase and N-sulfotransferase 3. (908 aa)
IMPA1Inositol monophosphatase 1. (414 aa)
GYG1Glycogenin 1. (370 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (443 aa)
B3GNT8UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8. (625 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (646 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
ENSECAP00000028904Uncharacterized protein. (143 aa)
IMPA2Inositol-1-monophosphatase. (293 aa)
LOC102148379Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (429 aa)
NANSN-acetylneuraminate synthase. (425 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (824 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (452 aa)
WDR5WD repeat domain 5. (342 aa)
PPARGC1APPARG coactivator 1 alpha. (839 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (454 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (556 aa)
GLT8D2Glycosyltransferase 8 domain containing 2. (350 aa)
NDST4N-deacetylase and N-sulfotransferase 4. (872 aa)
CHST8Carbohydrate sulfotransferase. (458 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
PGK2Phosphoglycerate kinase 2; Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis. (417 aa)
ENSECAP00000039423Uncharacterized protein. (111 aa)
RGNRegucalcin. (299 aa)
CHST11Carbohydrate sulfotransferase. (372 aa)
CHST13Carbohydrate sulfotransferase. (365 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (826 aa)
CHST9Carbohydrate sulfotransferase. (471 aa)
HAS3Hyaluronan synthase 3. (701 aa)
HAS1Hyaluronan synthase 1. (582 aa)
GYG2Glycogenin 2. (436 aa)
C1QTNF12C1q and TNF related 12. (300 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (384 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase. (517 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (987 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
SDSSerine dehydratase. (359 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (750 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (402 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.