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| | SSC4D | Scavenger receptor cysteine rich family member with 4 domains. (586 aa) |
| | PIDD1 | P53-induced death domain protein 1. (915 aa) |
| | SPPL3 | Signal peptide peptidase like 3. (434 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (569 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | PCSK7 | Proprotein convertase subtilisin/kexin type 7. (874 aa) |
| | ENSECAP00000034428 | Uncharacterized protein. (97 aa) |
| | PCSK1N | Proprotein convertase subtilisin/kexin type 1 inhibitor. (260 aa) |
| | CTSH | Uncharacterized protein; Belongs to the peptidase C1 family. (386 aa) |
| | LOC111775413 | Peptidase S1 domain-containing protein. (237 aa) |
| | METAP2 | Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (478 aa) |
| | ECEL1 | Endothelin converting enzyme like 1. (819 aa) |
| | COMP | Cartilage oligomeric matrix protein. (793 aa) |
| | FKRP | Fukutin related protein. (495 aa) |
| | PRSS12 | Serine protease 12; Belongs to the peptidase S1 family. (875 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (632 aa) |
| | ASPH | Aspartate beta-hydroxylase. (790 aa) |
| | ENSECAP00000039928 | Uncharacterized protein. (183 aa) |
| | DISP1 | Dispatched RND transporter family member 1. (1690 aa) |
| | SPG7 | SPG7 matrix AAA peptidase subunit, paraplegin. (791 aa) |
| | RCE1 | Ras converting CAAX endopeptidase 1. (590 aa) |
| | NCSTN | Nicastrin. (709 aa) |
| | ENSECAP00000041588 | Uncharacterized protein. (152 aa) |
| | LOC100052875 | AAA domain-containing protein. (715 aa) |
| | APH1A | Aph-1 homolog A, gamma-secretase subunit. (274 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | PISD | Phosphatidylserine decarboxylase. (417 aa) |
| | SEC11C | Signal peptidase complex catalytic subunit SEC11. (216 aa) |
| | TLL1 | Metalloendopeptidase. (1041 aa) |
| | PAWR | Uncharacterized protein. (596 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (358 aa) |
| | SEC11A | Signal peptidase complex catalytic subunit SEC11. (183 aa) |
| | GLI3 | GLI family zinc finger 3. (1581 aa) |
| | PCSK4 | Uncharacterized protein. (810 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (347 aa) |
| | PLAT | Plasminogen activator, tissue type. (615 aa) |
| | YME1L1 | YME1 like 1 ATPase. (771 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (488 aa) |
| | MEP1A | Meprin A subunit. (773 aa) |
| | KLKB1 | Kallikrein B1; Belongs to the peptidase S1 family. (892 aa) |
| | LOC111775628 | Uncharacterized protein; Belongs to the peptidase C1 family. (428 aa) |
| | MYRFL | Myelin regulatory factor like. (910 aa) |
| | APH1B | Aph-1 homolog B, gamma-secretase subunit. (524 aa) |
| | PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (619 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (868 aa) |
| | PCSK6 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (975 aa) |
| | MMEL1 | Membrane metalloendopeptidase like 1. (876 aa) |
| | MMP16 | Matrix metallopeptidase 16. (622 aa) |
| | CTSV | Cathepsin V; Belongs to the peptidase C1 family. (394 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (892 aa) |
| | LOC100069322 | Uncharacterized protein; Belongs to the peptidase C14A family. (350 aa) |
| | AFG3L2 | AFG3 like matrix AAA peptidase subunit 2. (837 aa) |
| | YIPF5 | Protein YIPF. (259 aa) |
| | HM13 | Histocompatibility minor 13. (426 aa) |
| | ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif 3. (1201 aa) |
| | CPXM2 | Carboxypeptidase X, M14 family member 2. (760 aa) |
| | CASP1 | Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...] (405 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (478 aa) |
| | CPN1 | Carboxypeptidase N subunit 1. (462 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | SPRTN | SprT-like N-terminal domain. (492 aa) |
| | SPCS1 | Signal peptidase complex subunit 1. (169 aa) |
| | F3 | Coagulation factor III, tissue factor. (388 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) |
| | SCG5 | Secretogranin V. (212 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (536 aa) |
| | PARL | Presenilin associated rhomboid like. (513 aa) |
| | PMPCA | Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family. (525 aa) |
| | BMP1 | Metalloendopeptidase. (1083 aa) |
| | APOH | Apolipoprotein H. (345 aa) |
| | MYRF | Myelin regulatory factor. (1186 aa) |
| | C1R | Complement C1r; Belongs to the peptidase S1 family. (705 aa) |
| | LOC100067869 | Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (347 aa) |
| | F9 | Coagulation factor IX. (457 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (212 aa) |
| | KLK1 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa) |
| | CPXM1 | Carboxypeptidase X, M14 family member 1. (732 aa) |
| | SPON1 | Spondin 1. (807 aa) |
| | PCSK1 | Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (754 aa) |
| | CPD | Carboxypeptidase D. (1385 aa) |
| | IMMP1L | Mitochondrial inner membrane protease subunit. (166 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (793 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (439 aa) |
| | ATP23 | Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family. (247 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1053 aa) |
| | REN | Renin; Belongs to the peptidase A1 family. (407 aa) |
| | FXN | Frataxin. (211 aa) |
| | CNTN2 | Contactin 2. (1040 aa) |
| | TBC1D10A | TBC1 domain family member 10A. (509 aa) |
| | XPNPEP3 | X-prolyl aminopeptidase 3. (508 aa) |
| | DHCR24 | 24-dehydrocholesterol reductase. (516 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | ADAM19 | ADAM metallopeptidase domain 19. (909 aa) |
| | METAP1 | Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (526 aa) |
| | STOML2 | Stomatin like 2. (356 aa) |
| | GLG1 | Golgi glycoprotein 1. (1247 aa) |
| | ECE1 | Endothelin converting enzyme 1. (779 aa) |
| | ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif 2. (1423 aa) |
| | SPCS3 | Signal peptidase complex subunit 3. (180 aa) |
| | ECE2 | Endothelin converting enzyme 2. (883 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (275 aa) |
| | PGK1 | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. (417 aa) |
| | CPM | Carboxypeptidase M. (443 aa) |
| | TLL2 | Metalloendopeptidase. (1020 aa) |
| | F7DW27_HORSE | Peptidase S1 domain-containing protein. (134 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | IMMP2L | Mitochondrial inner membrane protease subunit. (181 aa) |
| | PMPCB | Peptidase, mitochondrial processing beta subunit; Belongs to the peptidase M16 family. (551 aa) |
| | C1RL | Complement C1r subcomponent like; Belongs to the peptidase S1 family. (485 aa) |
| | KLK13 | Kallikrein related peptidase 13; Belongs to the peptidase S1 family. (279 aa) |
| | SCARA5 | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] (526 aa) |
| | CASP4 | Uncharacterized protein; Belongs to the peptidase C14A family. (370 aa) |
| | CPZ | Carboxypeptidase Z. (644 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa) |
| | C2CD3 | C2 domain containing 3 centriole elongation regulator. (2342 aa) |
| | PHEX | Phosphate regulating endopeptidase homolog X-linked. (749 aa) |
| | KLK1E2 | Kallikrein-1E2; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily. (261 aa) |
| | CD6 | CD6 molecule. (673 aa) |
| | F12 | Coagulation factor XII. (615 aa) |
| | LGMN | Legumain. (433 aa) |
| | DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) |
| | CIDEB | Cell death inducing DFFA like effector b. (222 aa) |
| | FGB | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (495 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | CLN5 | Uncharacterized protein. (352 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | TMPRSS12 | Transmembrane serine protease 12; Belongs to the peptidase S1 family. (298 aa) |
| | CPE | Carboxypeptidase E. (476 aa) |
| | TYSND1 | Serine protease; Belongs to the peptidase S1B family. (566 aa) |
| | OMA1 | OMA1 zinc metallopeptidase. (518 aa) |
| | MMP14 | Matrix metallopeptidase 14. (581 aa) |
| | TMEM208 | Transmembrane protein 208. (173 aa) |
| | MIPEP | Mitochondrial intermediate peptidase. (713 aa) |
| | ADAM10 | ADAM metallopeptidase domain 10. (748 aa) |
| | SDE2 | SDE2 telomere maintenance homolog. (453 aa) |
| | PCSK5 | Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1886 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | PSENEN | Presenilin enhancer, gamma-secretase subunit. (101 aa) |
| | PLAU | Plasminogen activator, urokinase. (433 aa) |
| | PRSS48 | Serine protease 48; Belongs to the peptidase S1 family. (303 aa) |
| | SPCS2 | Signal peptidase complex subunit 2. (226 aa) |
| | CORIN | Corin, serine peptidase. (1208 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (464 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (470 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | PCSK2 | Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (639 aa) |
| | ASPRV1 | Aspartic peptidase retroviral like 1. (374 aa) |
| | F11 | Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa) |
| | DDI2 | DNA damage inducible 1 homolog 2. (399 aa) |
| | PITRM1 | Pitrilysin metallopeptidase 1. (1035 aa) |
| | PTCH1 | Patched 1. (1490 aa) |
