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| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (764 aa) |
| | SF1 | Splicing factor 1. (639 aa) |
| | ETFBKMT | Electron transfer flavoprotein subunit beta lysine methyltransferase. (299 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (879 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (868 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (757 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (855 aa) |
| | LDLR | Low density lipoprotein receptor. (937 aa) |
| | ENSECAP00000052143 | Anaphylatoxin-like domain-containing protein. (78 aa) |
| | LOC100060505 | Uncharacterized protein. (1662 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | TPM1 | Tropomyosin 1; Belongs to the tropomyosin family. (591 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (732 aa) |
| | AADAC | Arylacetamide deacetylase. (399 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (568 aa) |
| | ENSECAP00000047374 | Uncharacterized protein. (56 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (743 aa) |
| | RORA | RAR related orphan receptor A. (527 aa) |
| | LTK | Tyrosine-protein kinase receptor. (891 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (587 aa) |
| | LOC100063866 | AIG1-type G domain-containing protein. (413 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2436 aa) |
| | DISP3 | Dispatched RND transporter family member 3. (1393 aa) |
| | LOC100630393 | AIG1-type G domain-containing protein. (315 aa) |
| | SCAP | SREBF chaperone. (1280 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (457 aa) |
| | LGALS12 | Galectin. (325 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | SPHK1 | Sphingosine kinase 1. (459 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (467 aa) |
| | LYN | Tyrosine-protein kinase. (533 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa) |
| | CLCN2 | Chloride channel protein. (980 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (171 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | SEC14L3 | SEC14 like lipid binding 3. (537 aa) |
| | ABHD5 | Abhydrolase domain containing 5. (378 aa) |
| | ENSECAP00000039988 | Prohibitin. (299 aa) |
| | STAT5A | Signal transducer and activator of transcription. (800 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (867 aa) |
| | APOC3 | Apolipoprotein C-III; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tigh [...] (117 aa) |
| | PLA2G6 | Phospholipase A2 group VI. (1134 aa) |
| | CD74 | CD74 molecule. (272 aa) |
| | LOC100060824 | Dimethylaniline monooxygenase [N-oxide-forming]. (516 aa) |
| | ATG14 | Autophagy related 14. (510 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (591 aa) |
| | MACROH2A1 | H2A histone family member Y. (414 aa) |
| | APOBEC1 | Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (492 aa) |
| | GOLM1 | Golgi membrane protein 1. (462 aa) |
| | PDK1 | Protein-serine/threonine kinase. (438 aa) |
| | APOB | Apolipoprotein B. (4423 aa) |
| | ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa) |
| | ENSECAP00000036553 | Uncharacterized protein. (46 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (189 aa) |
| | STAT5B | Signal transducer and activator of transcription. (825 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1896 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (804 aa) |
| | ANAPC15 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (301 aa) |
| | LOC100146250 | AIG1-type G domain-containing protein. (315 aa) |
| | CGA | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (132 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa) |
| | LOC100146242 | ABC transmembrane type-1 domain-containing protein. (379 aa) |
| | ENSECAP00000033220 | AIG1-type G domain-containing protein. (267 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1299 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1331 aa) |
| | LOC100070407 | ABC transporter domain-containing protein. (230 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (897 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | RUBCN | Rubicon autophagy regulator. (1013 aa) |
| | SIRT1 | Sirtuin 1. (737 aa) |
| | SORL1 | Sortilin related receptor 1. (2255 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (356 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (215 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (741 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1468 aa) |
| | DGKZ | Diacylglycerol kinase. (1111 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | CCDC3 | Coiled-coil domain containing 3. (274 aa) |
| | ACADVL | Acyl-CoA dehydrogenase very long chain. (657 aa) |
| | SAMD8 | Sterile alpha motif domain containing 8. (478 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1740 aa) |
| | DNAJC15 | J domain-containing protein. (233 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (422 aa) |
| | DAB2IP | DAB2 interacting protein. (1166 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (249 aa) |
| | ENSECAP00000024196 | DAGKa domain-containing protein. (363 aa) |
| | BBS4 | Bardet-Biedl syndrome 4. (531 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1481 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity). (350 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | ENSECAP00000023457 | Uncharacterized protein. (189 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1336 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | PLA2G3 | Phospholipase A2 group III. (513 aa) |
| | CCN1 | Cellular communication network factor 1. (382 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. (1021 aa) |
| | PDE3B | Phosphodiesterase. (1125 aa) |
| | FMC1 | Formation of mitochondrial complex V assembly factor 1 homolog. (113 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (443 aa) |
| | TTC39B | Tetratricopeptide repeat domain 39B. (706 aa) |
| | CRTC3 | CREB regulated transcription coactivator 3. (619 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (787 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | CD19 | CD19 molecule. (559 aa) |
| | AADAC-2 | Arylacetamide deacetylase. (278 aa) |
| | FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | TM6SF2 | Transmembrane 6 superfamily member 2. (376 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (486 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | ZFP69B | ZFP69 zinc finger protein B. (534 aa) |
| | ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3. (234 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (467 aa) |
| | EPHA8 | EPH receptor A8. (1002 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (633 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | CREBL2 | cAMP responsive element binding protein like 2. (153 aa) |
| | REST | RE1 silencing transcription factor. (1039 aa) |
| | DGKQ | Diacylglycerol kinase. (931 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (439 aa) |
| | SOX9 | SRY-box 9. (509 aa) |
| | APOD | Apolipoprotein D. (213 aa) |
| | ZFP69 | ZFP69 zinc finger protein. (523 aa) |
| | PSAP | Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (526 aa) |
| | MLXIPL | MLX interacting protein like. (905 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (549 aa) |
| | BMP2 | Bone morphogenetic protein 2. (397 aa) |
| | FMO1 | Flavin-containing monooxygenase. (1023 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (668 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (278 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) |
| | BMP6 | Bone morphogenetic protein 6. (506 aa) |
| | SEC14L2 | Uncharacterized protein. (426 aa) |
| | MTMR3 | Myotubularin related protein 3. (1202 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) |
| | MTMR2 | Myotubularin related protein 2. (643 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | BSCL2 | BSCL2 lipid droplet biogenesis associated, seipin. (462 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | CERS2 | Ceramide synthase 2. (652 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (471 aa) |
| | STOML2 | Stomatin like 2. (356 aa) |
| | PANK2 | Pantothenate kinase 2. (449 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (547 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1013 aa) |
| | TEK | TEK receptor tyrosine kinase. (1153 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | RUBCNL | Rubicon like autophagy enhancer. (667 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa) |
| | RETN | Resistin. (110 aa) |
| | ASXL3 | ASXL transcriptional regulator 3. (2248 aa) |
| | PODN | Podocan. (617 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (447 aa) |
| | TTC39A | Tetratricopeptide repeat domain 39A. (581 aa) |
| | MBOAT7 | Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1321 aa) |
| | ANGPTL8 | Angiopoietin like 8. (198 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (757 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (298 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (350 aa) |
| | RARRES2 | Retinoic acid receptor responder 2. (163 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (654 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | OPA3 | Outer mitochondrial membrane lipid metabolism regulator OPA3. (182 aa) |
| | LOC100063059 | SCY domain-containing protein. (131 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (529 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | DDX20 | DEAD-box helicase 20. (824 aa) |
| | SAA1 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (162 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (571 aa) |
| | PSAPL1 | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. (513 aa) |
| | LOC111770212 | C-C motif chemokine. (100 aa) |
| | DAGLB | Diacylglycerol lipase beta. (672 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa) |
| | ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (564 aa) |
| | IDH1 | Isocitrate dehydrogenase (NADP(+)) 1, cytosolic. (641 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (696 aa) |
| | PNPLA2 | Patatin like phospholipase domain containing 2. (491 aa) |
| | F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (719 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) |
| | ERLIN2 | ER lipid raft associated 2. (339 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | APOA2 | Apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. (100 aa) |
| | SCT | GLUCAGON domain-containing protein. (57 aa) |
| | ARMC5 | Armadillo repeat containing 5. (940 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (265 aa) |
| | ADIPOR1 | Adiponectin receptor 1. (375 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (639 aa) |
| | TYSND1 | Serine protease; Belongs to the peptidase S1B family. (566 aa) |
| | FABP5 | Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (158 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (528 aa) |
| | PDK4 | Protein-serine/threonine kinase. (447 aa) |
| | ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | ANGPTL3 | Angiopoietin like 3. (469 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | GIP | Gastric inhibitory polypeptide. (145 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2156 aa) |
| | NR1D2 | Nuclear receptor subfamily 1 group D member 2. (591 aa) |
| | FGR | Tyrosine-protein kinase. (527 aa) |
| | SPHK2 | Sphingosine kinase 2. (654 aa) |
| | ALK | Tyrosine-protein kinase receptor. (1623 aa) |
| | PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1. (261 aa) |
| | BMP5 | Bone morphogenetic protein 5. (462 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (336 aa) |
| | CTDNEP1 | CTD nuclear envelope phosphatase 1. (244 aa) |
| | CD81 | Tetraspanin. (393 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (605 aa) |
| | SIK1 | Uncharacterized protein. (826 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | THRSP | Thyroid hormone responsive. (150 aa) |
| | LRRN4CL | LRRN4 C-terminal like. (236 aa) |
| | LOC100069973 | Uncharacterized protein. (589 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | ADRA2A | Adrenoceptor alpha 2A. (465 aa) |
| | MID1IP1 | MID1 interacting protein 1. (182 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (301 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) |
| | HCAR1 | Hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (346 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (353 aa) |
