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| | PRKX | Protein kinase X-linked; Belongs to the protein kinase superfamily. (356 aa) |
| | NKX2-3 | NK2 homeobox 3. (370 aa) |
| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (303 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (692 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (388 aa) |
| | TOB2 | Transducer of ERBB2, 2. (345 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) |
| | SLC4A1 | Anion exchange protein. (934 aa) |
| | ADAR | Adenosine deaminase RNA specific. (1171 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (397 aa) |
| | CALCR | Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (475 aa) |
| | CLEC1B | C-type lectin domain family 1 member B. (228 aa) |
| | TRIM10 | Tripartite motif containing 10. (481 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (968 aa) |
| | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) |
| | TET2 | Tet methylcytosine dioxygenase 2. (2011 aa) |
| | RUNX1 | RUNX family transcription factor 1. (537 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (215 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (451 aa) |
| | GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (389 aa) |
| | BCL6 | BCL6 transcription repressor. (699 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (464 aa) |
| | PML | Promyelocytic leukemia. (881 aa) |
| | TSPO2 | Translocator protein 2. (171 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1142 aa) |
| | CD81 | Tetraspanin. (393 aa) |
| | SH2B3 | SH2B adaptor protein 3. (561 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (632 aa) |
| | HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (139 aa) |
| | FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1057 aa) |
| | EPHA2 | EPH receptor A2. (975 aa) |
| | SRF | Serum response factor. (512 aa) |
| | CD4 | CD4 molecule. (460 aa) |
| | NF1 | Neurofibromin 1. (3024 aa) |
| | VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (448 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor. (152 aa) |
| | EP300 | E1A binding protein p300. (2430 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (611 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2009 aa) |
| | JAK2 | Tyrosine-protein kinase. (1131 aa) |
| | OCSTAMP | Osteoclast stimulatory transmembrane protein. (505 aa) |
| | AHSP | Alpha hemoglobin stabilizing protein. (102 aa) |
| | WASF2 | WASP family member 2. (498 aa) |
| | ETV2 | ETS variant 2. (248 aa) |
| | GATA1 | GATA binding protein 1. (486 aa) |
| | PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | C1H15orf41 | Chromosome 1 C15orf41 homolog. (304 aa) |
| | BATF3 | Basic leucine zipper ATF-like transcription factor 3. (253 aa) |
| | TSPAN2 | Tetraspanin. (309 aa) |
| | NCOA6 | Nuclear receptor coactivator 6. (2062 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | ATP5IF1 | ATP synthase inhibitory factor subunit 1. (108 aa) |
| | SRC | Tyrosine-protein kinase. (551 aa) |
| | CEBPE | CCAAT/enhancer-binding protein. (281 aa) |
| | LYAR | Ly1 antibody reactive. (388 aa) |
| | LOC111770212 | C-C motif chemokine. (100 aa) |
| | KIT | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa) |
| | ADD1 | Adducin 1. (771 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (381 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (467 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa) |
| | CBFB | Core-binding factor subunit beta. (188 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (910 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (637 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (298 aa) |
| | PDE1B | NCK associated protein 1 like. (1182 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (498 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | JAGN1 | Jagunal homolog 1. (276 aa) |
| | PLA2G10 | Phospholipase A(2). (160 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (318 aa) |
| | CAMK4 | Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa) |
| | OSTM1 | Osteoclastogenesis associated transmembrane protein 1. (334 aa) |
| | PRDX3 | Peroxiredoxin 3. (374 aa) |
| | IREB2 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (964 aa) |
| | TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | CSF1 | Colony stimulating factor 1. (630 aa) |
| | ABCB10 | ATP binding cassette subfamily B member 10. (728 aa) |
| | FLVCR1 | Feline leukemia virus subgroup C cellular receptor 1. (555 aa) |
| | CIB1 | Calcium and integrin binding 1. (191 aa) |
| | SRP54 | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (507 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa) |
| | KAT8 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (459 aa) |
| | IL25 | Interleukin 25. (161 aa) |
| | DNASE2 | Deoxyribonuclease 2, lysosomal. (353 aa) |
| | DCSTAMP | Dendrocyte expressed seven transmembrane protein. (470 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (767 aa) |
| | ARID4A | AT-rich interaction domain 4A. (1273 aa) |
| | GLO1 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | BAP1 | Ubiquitin carboxyl-terminal hydrolase. (726 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (709 aa) |
| | ZBTB46 | Zinc finger and BTB domain containing 46. (590 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa) |
| | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa) |
| | FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (452 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa) |
| | MYH9 | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa) |
| | APP | Amyloid beta precursor protein. (811 aa) |
| | CASP3 | Caspase-3-like protein; Belongs to the peptidase C14A family. (277 aa) |
| | MPIG6B | Megakaryocyte and platelet inhibitory receptor G6b. (218 aa) |
| | EPB42 | Erythrocyte membrane protein band 4.2. (714 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | GAB3 | GRB2 associated binding protein 3. (708 aa) |
| | GPR183 | G-protein coupled receptor 183-like protein; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | IAPP | Islet amyloid polypeptide. (119 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (340 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (478 aa) |
| | LRRK1 | Leucine rich repeat kinase 1. (2014 aa) |
| | TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (767 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (606 aa) |
| | VPS33B | VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (617 aa) |
| | CCN4 | Cellular communication network factor 4. (368 aa) |
| | TMEM14C | Transmembrane protein 14C. (115 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (222 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (778 aa) |
| | GATA3 | GATA binding protein 3. (445 aa) |
| | CBFA2T3 | CBFA2/RUNX1 translocation partner 3. (658 aa) |
| | LBR | Lamin B receptor. (617 aa) |
| | CD109 | CD109 molecule. (1520 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (432 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | PABPC4 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (708 aa) |
| | IRF4 | Interferon regulatory factor 4. (606 aa) |
| | CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (532 aa) |
| | PIR | Pirin; Belongs to the pirin family. (300 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (794 aa) |
| | SLC25A38 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa) |
| | UFL1 | UFM1 specific ligase 1. (791 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (769 aa) |
| | KMT2E | Lysine methyltransferase 2E. (1857 aa) |
| | SIRT1 | Sirtuin 1. (737 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | RCOR1 | REST corepressor 1. (528 aa) |
| | GP9 | Glycoprotein IX platelet. (177 aa) |
| | HOXB7 | Homeobox B7. (250 aa) |
| | FOXP1 | Forkhead box P1. (691 aa) |
| | KLF1 | Kruppel like factor 1. (360 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (294 aa) |
| | ENSECAP00000033220 | AIG1-type G domain-containing protein. (267 aa) |
| | EFNA2 | Ephrin A2; Belongs to the ephrin family. (214 aa) |
| | LOC100146250 | AIG1-type G domain-containing protein. (315 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | ENSECAP00000034773 | Uncharacterized protein. (135 aa) |
| | IL20 | Interleukin 20. (248 aa) |
| | STAT5B | Signal transducer and activator of transcription. (825 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (986 aa) |
| | SP3 | Sp3 transcription factor. (790 aa) |
| | ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa) |
| | DHRS7B | Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (399 aa) |
| | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone. (267 aa) |
| | LTBR | Lymphotoxin beta receptor. (434 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (413 aa) |
| | ACTN1 | Actinin alpha 1. (959 aa) |
| | RB1 | RB transcriptional corepressor 1. (965 aa) |
| | THOC5 | THO complex 5. (705 aa) |
| | ZNF385A | Zinc finger protein 385A. (435 aa) |
| | SBNO2 | Strawberry notch homolog 2. (1370 aa) |
| | LYN | Tyrosine-protein kinase. (533 aa) |
| | JAK3 | Tyrosine-protein kinase. (1139 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) |
| | BATF2 | Basic leucine zipper ATF-like transcription factor 2. (272 aa) |
| | MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1. (1046 aa) |
| | WDR1 | WD repeat domain 1. (695 aa) |
| | LOC100630393 | AIG1-type G domain-containing protein. (315 aa) |
| | ZFP36 | Uncharacterized protein. (662 aa) |
| | LOC100063866 | AIG1-type G domain-containing protein. (413 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | CEBPA | CCAAT enhancer binding protein alpha. (358 aa) |
| | SNX10 | Sorting nexin 10. (201 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (587 aa) |
| | IKZF1 | IKAROS family zinc finger 1. (529 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | IL17C | Interleukin 17C. (197 aa) |
| | ALAS2 | 5-aminolevulinate synthase. (587 aa) |
| | IRF8 | Interferon regulatory factor 8. (492 aa) |
| | MITF | Melanocyte inducing transcription factor. (641 aa) |
| | DMTN | Dematin actin binding protein. (405 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (647 aa) |
| | FASN | Fatty acid synthase. (3470 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | MAEA | Macrophage erythroblast attacher. (434 aa) |
| | UBA5 | Ubiquitin like modifier activating enzyme 5. (404 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (214 aa) |
