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FOXO3 | Forkhead box O3. (671 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) | ||||
RAD23A | RAD23 homolog A, nucleotide excision repair protein. (363 aa) | ||||
DCP1A | Decapping mRNA 1A. (580 aa) | ||||
EXOSC9 | Exosome component 9. (440 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa) | ||||
TNRC6A | Trinucleotide repeat containing adaptor 6A. (1951 aa) | ||||
DHX36 | DEAH-box helicase 36. (1029 aa) | ||||
PACSIN3 | Protein kinase C and casein kinase substrate in neurons 3. (428 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa) | ||||
PTPN1 | Protein tyrosine phosphatase non-receptor type 1. (493 aa) | ||||
SH3GLB1 | SH3 domain containing GRB2 like, endophilin B1. (402 aa) | ||||
TRIM6 | Uncharacterized protein. (490 aa) | ||||
CNOT2 | CCR4-NOT transcription complex subunit 2. (844 aa) | ||||
CBFA2T3 | CBFA2/RUNX1 translocation partner 3. (658 aa) | ||||
ATF6 | Activating transcription factor 6. (669 aa) | ||||
DCP1B | Decapping mRNA 1B. (620 aa) | ||||
WIPI1 | WD repeat domain, phosphoinositide interacting 1. (456 aa) | ||||
YTHDF1 | YTH N6-methyladenosine RNA binding protein 1. (624 aa) | ||||
RNF180 | Ring finger protein 180. (592 aa) | ||||
PLIN5 | Perilipin; Belongs to the perilipin family. (457 aa) | ||||
NPRL3 | NPR3 like, GATOR1 complex subunit. (664 aa) | ||||
CNOT3 | CCR4-NOT transcription complex subunit 3. (779 aa) | ||||
ZFP36 | Uncharacterized protein. (662 aa) | ||||
CDK16 | Cyclin dependent kinase 16. (573 aa) | ||||
ENSECAP00000045503 | Endo/exonuclease/phosphatase domain-containing protein. (538 aa) | ||||
PLEKHF1 | Pleckstrin homology and FYVE domain containing 1. (330 aa) | ||||
PATL1 | PAT1 homolog 1, processing body mRNA decay factor. (874 aa) | ||||
PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (587 aa) | ||||
SESN1 | Sestrin 1. (551 aa) | ||||
DET1 | DET1 partner of COP1 E3 ubiquitin ligase. (709 aa) | ||||
ENSECAP00000047374 | Uncharacterized protein. (56 aa) | ||||
AADAC | Arylacetamide deacetylase. (399 aa) | ||||
RC3H1 | Ring finger and CCCH-type domains 1. (1131 aa) | ||||
ABCD1 | ATP binding cassette subfamily D member 1. (732 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (844 aa) | ||||
RNF14 | RBR-type E3 ubiquitin transferase. (467 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1637 aa) | ||||
SAMD4B | Sterile alpha motif domain containing 4B. (786 aa) | ||||
BCAP31 | B cell receptor associated protein 31. (280 aa) | ||||
DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (325 aa) | ||||
SH3D19 | SH3 domain containing 19. (1072 aa) | ||||
NOP53 | NOP53 ribosome biogenesis factor. (549 aa) | ||||
NKD2 | NKD inhibitor of WNT signaling pathway 2. (553 aa) | ||||
DAPK1 | Death associated protein kinase 1. (1457 aa) | ||||
TNFRSF1B | TNF receptor superfamily member 1B. (481 aa) | ||||
ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) | ||||
FBXW9 | F-box and WD repeat domain containing 9. (477 aa) | ||||
ZBTB20 | Zinc finger and BTB domain containing 20. (757 aa) | ||||
CALCOCO2 | Calcium binding and coiled-coil domain 2. (502 aa) | ||||
PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (386 aa) | ||||
PRXL2C | Peroxiredoxin like 2C. (226 aa) | ||||
PABPN1L | Poly(A) binding protein nuclear 1 like, cytoplasmic. (271 aa) | ||||
TRIB3 | Tribbles pseudokinase 3. (353 aa) | ||||
LRRC27 | Leucine rich repeat containing 27. (521 aa) | ||||
HMOX1 | Heme oxygenase 1. (490 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) | ||||
FOXO1 | Forkhead box O1. (651 aa) | ||||
TOB1 | Transducer of ERBB2, 1. (600 aa) | ||||
FAM122A | Family with sequence similarity 122A. (329 aa) | ||||
NANOS1 | Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (289 aa) | ||||
SESN2 | Sestrin 2. (481 aa) | ||||
ADRA2A | Adrenoceptor alpha 2A. (465 aa) | ||||
SOCS4 | Suppressor of cytokine signaling 4. (441 aa) | ||||
LOC100147364 | Ribonuclease UK114-like protein. (137 aa) | ||||
BAG3 | BCL2 associated athanogene 3. (582 aa) | ||||
PDE12 | Phosphodiesterase 12. (609 aa) | ||||
CNOT7 | CCR4-NOT transcription complex subunit 7. (285 aa) | ||||
NANOS2 | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa) | ||||
RNF152 | Ring finger protein 152. (203 aa) | ||||
LOC100054534 | Uncharacterized protein. (511 aa) | ||||
TRIM21 | Tripartite motif containing 21. (469 aa) | ||||
FBXO22 | FIST_C domain-containing protein. (404 aa) | ||||
EXOSC7 | Exosome component 7. (321 aa) | ||||
MEFV | MEFV innate immuity regulator, pyrin. (117 aa) | ||||
PRAF2 | WD repeat domain 45. (361 aa) | ||||
CLU | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (450 aa) | ||||
TRIM67 | Tripartite motif containing 67. (783 aa) | ||||
AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa) | ||||
ZSWIM8 | Zinc finger SWIM-type containing 8. (1842 aa) | ||||
RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) | ||||
OPTN | Optineurin. (574 aa) | ||||
TRIM68 | Tripartite motif containing 68. (484 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (139 aa) | ||||
TARDBP | TAR DNA-binding protein 43-like protein. (414 aa) | ||||
HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (215 aa) | ||||
CNOT6 | CCR4-NOT transcription complex subunit 6. (557 aa) | ||||
SH3RF3 | SH3 domain containing ring finger 3. (879 aa) | ||||
ATG101 | Autophagy related 101. (218 aa) | ||||
PRICKLE1 | Prickle planar cell polarity protein 1. (832 aa) | ||||
ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) | ||||
BECN1 | Beclin 1. (448 aa) | ||||
RAB3GAP2 | Uncharacterized protein. (1393 aa) | ||||
AXIN2 | Axin 2. (843 aa) | ||||
LRSAM1 | Leucine rich repeat and sterile alpha motif containing 1. (727 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (604 aa) | ||||
SESN3 | Sestrin 3. (488 aa) | ||||
SMURF1 | E3 ubiquitin-protein ligase. (757 aa) | ||||
ZFP36L2 | ZFP36 ring finger protein like 2. (510 aa) | ||||
TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (239 aa) | ||||
BNIP3 | BCL2 interacting protein 3. (243 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1013 aa) | ||||
BTG2 | BTG anti-proliferation factor 2. (150 aa) | ||||
TPCN1 | Two pore segment channel 1. (818 aa) | ||||
VPS13D | Vacuolar protein sorting 13 homolog D. (4388 aa) | ||||
CDC20B | Cell division cycle 20B. (515 aa) | ||||
TRIM8 | Tripartite motif containing 8. (551 aa) | ||||
ITCH | E3 ubiquitin-protein ligase. (862 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (1059 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (231 aa) | ||||
SUPV3L1 | Suv3 like RNA helicase. (786 aa) | ||||
RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) | ||||
SMCR8 | SMCR8-C9orf72 complex subunit. (937 aa) | ||||
NANOS3 | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (176 aa) | ||||
TRIM34 | Uncharacterized protein. (496 aa) | ||||
SNX33 | Sorting nexin. (574 aa) | ||||
DEPDC5 | DEP domain containing 5. (1602 aa) | ||||
USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) | ||||
RALB | RAS like proto-oncogene B. (206 aa) | ||||
F7CNV6_HORSE | Uncharacterized protein. (1071 aa) | ||||
DXO | Decapping exoribonuclease. (397 aa) | ||||
GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
CDC20 | Cell division cycle 20. (499 aa) | ||||
PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1202 aa) | ||||
PRR5L | Proline rich 5 like. (368 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1358 aa) | ||||
DCN | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa) | ||||
DDRGK1 | DDRGK domain containing 1. (315 aa) | ||||
ZYG11A | Zyg-11 family member A, cell cycle regulator. (760 aa) | ||||
SMAD7 | Mothers against decapentaplegic homolog. (426 aa) | ||||
PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (801 aa) | ||||
TRIM71 | Tripartite motif containing 71. (868 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (270 aa) | ||||
TRIM65 | Tripartite motif containing 65. (517 aa) | ||||
DVL1 | Dishevelled segment polarity protein 1. (700 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
POLR2G | RNA polymerase II subunit G. (172 aa) | ||||
SH3RF1 | SH3 domain containing ring finger 1. (886 aa) | ||||
PUM1 | Pumilio RNA binding family member 1. (1223 aa) | ||||
METTL14 | Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa) | ||||
MLXIPL | MLX interacting protein like. (905 aa) | ||||
ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) | ||||
LOC100055155 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa) | ||||
APP | Amyloid beta precursor protein. (811 aa) | ||||
TSC2 | TSC complex subunit 2. (1817 aa) | ||||
CLUL1 | Clusterin; Belongs to the clusterin family. (465 aa) | ||||
NRDC | Nardilysin convertase. (1247 aa) | ||||
PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (439 aa) | ||||
RACK1 | WD_REPEATS_REGION domain-containing protein. (317 aa) | ||||
NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (633 aa) | ||||
FBXW7 | F-box and WD repeat domain containing 7. (754 aa) | ||||
GBA | Glucosylceramidase. (536 aa) | ||||
PLEKHN1 | Pleckstrin homology domain containing N1. (612 aa) | ||||
YTHDF2 | YTH N6-methyladenosine RNA binding protein 2. (580 aa) | ||||
AXIN1 | Axin 1. (939 aa) | ||||
AADAC-2 | Arylacetamide deacetylase. (278 aa) | ||||
EXOSC5 | Exosome component 5. (235 aa) | ||||
GIGYF2 | GRB10 interacting GYF protein 2. (1284 aa) | ||||
TRIM38 | Tripartite motif containing 38. (464 aa) | ||||
SH3RF2 | SH3 domain containing ring finger 2. (732 aa) | ||||
TFEB | Transcription factor EB. (522 aa) | ||||
GRSF1 | G-rich RNA sequence binding factor 1. (654 aa) | ||||
SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (597 aa) | ||||
DISC1 | DISC1 scaffold protein. (890 aa) | ||||
CCDC22 | Coiled-coil domain containing 22. (627 aa) | ||||
NOD1 | Nucleotide binding oligomerization domain containing 1. (993 aa) | ||||
NUB1 | Negative regulator of ubiquitin like proteins 1. (640 aa) | ||||
TRIM27 | Tripartite motif containing 27. (536 aa) | ||||
MEX3D | Mex-3 RNA binding family member D. (917 aa) | ||||
PAFAH1B2 | Platelet-activating factor acetylhydrolase I subunit beta-like protein. (229 aa) | ||||
PABPC1 | Uncharacterized protein. (648 aa) | ||||
CNOT6L | CCR4-NOT transcription complex subunit 6 like. (562 aa) | ||||
RAB3GAP1 | RAB3 GTPase activating protein catalytic subunit 1. (989 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
ENSECAP00000040460 | Uncharacterized protein. (104 aa) | ||||
AGBL4 | ATP/GTP binding protein like 4. (531 aa) | ||||
ABHD5 | Abhydrolase domain containing 5. (378 aa) | ||||
SH3BP4 | SH3 domain binding protein 4. (964 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (867 aa) | ||||
RIDA | Reactive intermediate imine deaminase A homolog. (137 aa) | ||||
GPD1 | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa) | ||||
LIN28B | Lin-28 homolog B. (258 aa) | ||||
PARN | Poly(A)-specific ribonuclease. (646 aa) | ||||
DCP2 | Decapping mRNA 2. (422 aa) | ||||
ADAM8 | Uncharacterized protein. (824 aa) | ||||
DIS3L2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (905 aa) | ||||
PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (591 aa) | ||||
SAMD4A | Sterile alpha motif domain containing 4A. (758 aa) | ||||
ATG16L1 | Autophagy related 16 like 1. (914 aa) | ||||
FZR1 | Fizzy and cell division cycle 20 related 1. (695 aa) | ||||
C23H9orf72 | Chromosome 23 C9orf72 homolog. (481 aa) | ||||
RC3H2 | Ring finger and CCCH-type domains 2. (1121 aa) | ||||
MKRN2 | Makorin ring finger protein 2. (502 aa) | ||||
ENSECAP00000036553 | Uncharacterized protein. (46 aa) | ||||
ZYG11B | Zyg-11 family member B, cell cycle regulator. (760 aa) | ||||
SNX4 | Sorting nexin 4. (475 aa) | ||||
FBXW8 | F-box and WD repeat domain containing 8. (851 aa) | ||||
SUPT5H | Transcription elongation factor SPT5. (1087 aa) | ||||
ZER1 | Zyg-11 related cell cycle regulator. (766 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (446 aa) | ||||
PIAS1 | Protein inhibitor of activated STAT 1. (678 aa) | ||||
DAB2 | DAB adaptor protein 2. (765 aa) | ||||
CPEB3 | Cytoplasmic polyadenylation element binding protein 3. (731 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa) | ||||
LOC100146242 | ABC transmembrane type-1 domain-containing protein. (379 aa) | ||||
NOCT | Nocturnin. (431 aa) | ||||
IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (569 aa) | ||||
TMEM59 | Transmembrane protein 59. (378 aa) | ||||
WAC | WW domain containing adaptor with coiled-coil. (1112 aa) | ||||
TNRC6B | Trinucleotide repeat containing adaptor 6B. (1872 aa) | ||||
HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1299 aa) | ||||
LOC100070407 | ABC transporter domain-containing protein. (230 aa) | ||||
EXOSC2 | Exosome component 2. (342 aa) | ||||
GTPBP1 | GTP binding protein 1. (669 aa) | ||||
AGTPBP1 | ATP/GTP binding protein 1. (1278 aa) | ||||
SVIP | Uncharacterized protein. (225 aa) | ||||
SIRT6 | Sirtuin 6. (407 aa) | ||||
EXOSC3 | Exosome component 3. (275 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
RNF217 | RBR-type E3 ubiquitin transferase. (540 aa) | ||||
SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (474 aa) | ||||
RNF144A | RBR-type E3 ubiquitin transferase. (361 aa) | ||||
SIRT1 | Sirtuin 1. (737 aa) | ||||
SIRT2 | Sirtuin 2. (462 aa) | ||||
SCOC | Short coiled-coil protein. (193 aa) | ||||
UFL1 | UFM1 specific ligase 1. (791 aa) | ||||
BBS7 | Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa) | ||||
MTDH | Metadherin. (615 aa) | ||||
ARIH1 | RBR-type E3 ubiquitin transferase. (554 aa) | ||||
SNX7 | Sorting nexin 7. (471 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) | ||||
COP1 | COP1 E3 ubiquitin ligase. (737 aa) | ||||
ZC3HAV1 | Zinc finger CCCH-type containing, antiviral 1. (1021 aa) | ||||
EIF4ENIF1 | Eukaryotic translation initiation factor 4E nuclear import factor 1. (985 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa) | ||||
LARP1 | La ribonucleoprotein domain family member 1. (1387 aa) | ||||
STING1 | Transmembrane protein 173. (405 aa) | ||||
FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (829 aa) | ||||
PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (921 aa) | ||||
RNF144B | RBR-type E3 ubiquitin transferase. (304 aa) | ||||
SNX9 | Sorting nexin. (621 aa) | ||||
SNX18 | Sorting nexin. (624 aa) | ||||
ATG2A | Autophagy related 2A. (1935 aa) | ||||
CCDC90B | Coiled-coil domain containing 90B. (267 aa) | ||||
FYCO1 | FYVE and coiled-coil domain containing 1. (1478 aa) | ||||
PATL2 | PAT1 homolog 2. (542 aa) | ||||
CNOT8 | CCR4-NOT transcription complex subunit 8. (292 aa) | ||||
DAGLB | Diacylglycerol lipase beta. (672 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) | ||||
TTC5 | Tetratricopeptide repeat domain 5. (458 aa) | ||||
DCPS | Decapping enzyme, scavenger. (337 aa) | ||||
PNLDC1 | PARN like, ribonuclease domain containing 1. (531 aa) | ||||
JMJD8 | WD repeat domain 24. (1023 aa) | ||||
EXOSC8 | Exosome component 8. (276 aa) | ||||
TNRC6C | Trinucleotide repeat containing adaptor 6C. (1917 aa) | ||||
TRIML2 | Tripartite motif family like 2. (427 aa) | ||||
PNPLA2 | Patatin like phospholipase domain containing 2. (491 aa) | ||||
RNF19B | RBR-type E3 ubiquitin transferase. (549 aa) | ||||
MID2 | Midline 2. (735 aa) | ||||
ZC3H18 | Zinc finger CCCH-type containing 18. (972 aa) | ||||
BTNL9 | Butyrophilin like 9. (545 aa) | ||||
TRIML1 | Tripartite motif family like 1. (462 aa) | ||||
DDA1 | DET1 and DDB1 associated 1. (102 aa) | ||||
SNX30 | Sorting nexin family member 30. (459 aa) | ||||
HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (392 aa) | ||||
TRIM13 | Tripartite motif containing 13. (409 aa) | ||||
RUFY4 | RUN and FYVE domain containing 4. (572 aa) | ||||
ARIH2 | RBR-type E3 ubiquitin transferase. (491 aa) | ||||
TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (221 aa) | ||||
YTHDF3 | YTH N6-methyladenosine RNA binding protein 3. (588 aa) | ||||
UPF1 | UPF1 RNA helicase and ATPase. (1127 aa) | ||||
CNOT1 | CCR4-NOT transcription complex subunit 1. (2376 aa) | ||||
LRRK2 | Leucine rich repeat kinase 2. (2528 aa) | ||||
ANKIB1 | RBR-type E3 ubiquitin transferase. (1103 aa) | ||||
CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) | ||||
LSM1 | U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
SGTA | Small glutamine rich tetratricopeptide repeat containing alpha. (313 aa) | ||||
CSNK1D | Casein kinase 1 delta; Belongs to the protein kinase superfamily. (428 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1382 aa) | ||||
HTT | Huntingtin. (3126 aa) | ||||
ENDOG | Endonuclease. (299 aa) | ||||
DTX3L | Deltex E3 ubiquitin ligase 3L. (739 aa) | ||||
FBXO7 | F-box protein 7. (550 aa) | ||||
ZC3H12A | Zinc finger CCCH-type containing 12A. (615 aa) | ||||
PINK1 | PTEN induced kinase 1. (585 aa) | ||||
TRIM32 | Tripartite motif containing 32. (653 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase. (528 aa) | ||||
RNF139 | Ring finger protein 139. (665 aa) | ||||
F6WH02_HORSE | FIST_C domain-containing protein. (381 aa) |