STRINGSTRING
TMEM119 TMEM119 GATA1 GATA1 ITGB3 ITGB3 CTHRC1 CTHRC1 BMP2 BMP2 HPSE HPSE CCN1 CCN1 ABL1 ABL1 LTF LTF LRP5 LRP5 ITGAV ITGAV SOX8 SOX8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM119Transmembrane protein 119. (275 aa)
GATA1GATA binding protein 1. (486 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
CTHRC1Collagen triple helix repeat containing 1. (244 aa)
BMP2Bone morphogenetic protein 2. (397 aa)
HPSEHeparanase. (544 aa)
CCN1Cellular communication network factor 1. (382 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
LTFLactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (715 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
ITGAVFamily with sequence similarity 171 member B; Belongs to the integrin alpha chain family. (1787 aa)
SOX8SRY-box 8. (460 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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