24 items (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1057 aa)
	MYOC	Myocilin. (490 aa)
	ACTL6A	Actin like 6A; Belongs to the actin family. (429 aa)
	ACTL6B	Actin like 6B; Belongs to the actin family. (426 aa)
	FEV	FEV transcription factor, ETS family member. (239 aa)
	NRCAM	Neuronal cell adhesion molecule. (1261 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	RB1	RB transcriptional corepressor 1. (965 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
	CNTN2	Contactin 2. (1040 aa)
	GLDN	Gliomedin. (620 aa)
	SCARF1	Scavenger receptor class F member 1. (830 aa)
	RND1	Rho family GTPase 1. (232 aa)
	LGI4	Leucine rich repeat LGI family member 4. (537 aa)
	SRRM4	Serine/arginine repetitive matrix 4. (601 aa)
	APP	Amyloid beta precursor protein. (811 aa)
	B4GALT5	Beta-1,4-galactosyltransferase 5. (388 aa)
	EPHA8	EPH receptor A8. (1002 aa)
	SCLT1	Sodium channel and clathrin linker 1. (688 aa)
	C1QL1	Complement C1q like 1. (258 aa)
	B4GALT6	Beta-1,4-galactosyltransferase 6. (382 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (609 aa)
	LOC102150786	Uncharacterized protein. (365 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL6A	ACTL6B	ENSECAP00000011372	ENSECAP00000012584	Actin like 6A; Belongs to the actin family.	Actin like 6B; Belongs to the actin family.	0.900
ACTL6B	ACTL6A	ENSECAP00000012584	ENSECAP00000011372	Actin like 6B; Belongs to the actin family.	Actin like 6A; Belongs to the actin family.	0.900
ACTL6B	SRRM4	ENSECAP00000012584	ENSECAP00000019201	Actin like 6B; Belongs to the actin family.	Serine/arginine repetitive matrix 4.	0.725
APP	CNTN2	ENSECAP00000019519	ENSECAP00000016418	Amyloid beta precursor protein.	Contactin 2.	0.667
APP	NRCAM	ENSECAP00000019519	ENSECAP00000014552	Amyloid beta precursor protein.	Neuronal cell adhesion molecule.	0.400
B4GALT5	B4GALT6	ENSECAP00000019827	ENSECAP00000015305	Beta-1,4-galactosyltransferase 5.	Beta-1,4-galactosyltransferase 6.	0.535
B4GALT6	B4GALT5	ENSECAP00000015305	ENSECAP00000019827	Beta-1,4-galactosyltransferase 6.	Beta-1,4-galactosyltransferase 5.	0.535
CNTN2	APP	ENSECAP00000016418	ENSECAP00000019519	Contactin 2.	Amyloid beta precursor protein.	0.667
CNTN2	NRCAM	ENSECAP00000016418	ENSECAP00000014552	Contactin 2.	Neuronal cell adhesion molecule.	0.778
FARP2	RND1	ENSECAP00000006633	ENSECAP00000018486	FERM, ARH/RhoGEF and pleckstrin domain protein 2.	Rho family GTPase 1.	0.459
GLDN	NRCAM	ENSECAP00000017377	ENSECAP00000014552	Gliomedin.	Neuronal cell adhesion molecule.	0.814
NRCAM	APP	ENSECAP00000014552	ENSECAP00000019519	Neuronal cell adhesion molecule.	Amyloid beta precursor protein.	0.400
NRCAM	CNTN2	ENSECAP00000014552	ENSECAP00000016418	Neuronal cell adhesion molecule.	Contactin 2.	0.778
NRCAM	GLDN	ENSECAP00000014552	ENSECAP00000017377	Neuronal cell adhesion molecule.	Gliomedin.	0.814
RND1	FARP2	ENSECAP00000018486	ENSECAP00000006633	Rho family GTPase 1.	FERM, ARH/RhoGEF and pleckstrin domain protein 2.	0.459
SRRM4	ACTL6B	ENSECAP00000019201	ENSECAP00000012584	Serine/arginine repetitive matrix 4.	Actin like 6B; Belongs to the actin family.	0.725