(38 nodes) Receptor clustering network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLITRK3	SLIT and NTRK like family member 3. (976 aa)
	PICK1	Protein interacting with PRKCA 1. (417 aa)
	ERBIN	Erbb2 interacting protein. (1461 aa)
	ITGAL	Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1168 aa)
	NLGN2	Neuroligin 2. (835 aa)
	SYNJ2BP	PDZ domain-containing protein. (145 aa)
	CHRDL1	Chordin like 1. (521 aa)
	FLNA	Filamin A. (2647 aa)
	PTN	Pleiotrophin. (192 aa)
	LRP4	LDL receptor related protein 4. (1905 aa)
	WDR19	WD repeat domain 19. (1342 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	PIGR	Polymeric immunoglobulin receptor. (862 aa)
	LRRC1	Leucine rich repeat containing 1. (614 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa)
	RER1	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (196 aa)
	RELN	Reelin. (3460 aa)
	SAV1	Salvador family WW domain containing protein 1. (384 aa)
	SSNA1	SS nuclear autoantigen 1. (120 aa)
	DVL1	Dishevelled segment polarity protein 1. (700 aa)
	GPHN	Gephyrin. (829 aa)
	DLG3	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa)
	AGRN	Agrin. (2071 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (938 aa)
	SHISA7	Shisa family member 7. (564 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1276 aa)
	SYNGAP1	Synaptic Ras GTPase activating protein 1. (1349 aa)
	NLGN1	Neuroligin 1. (823 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (975 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1807 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (591 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	SCRIB	Scribble planar cell polarity protein. (1690 aa)
	COLQ	Collagen like tail subunit of asymmetric acetylcholinesterase. (448 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (379 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	COLQ	ENSECAP00000035833	ENSECAP00000017456	Agrin.	Collagen like tail subunit of asymmetric acetylcholinesterase.	0.658
AGRN	ITGAL	ENSECAP00000035833	ENSECAP00000007728	Agrin.	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	0.429
AGRN	LRP4	ENSECAP00000035833	ENSECAP00000021146	Agrin.	LDL receptor related protein 4.	0.995
CDK5	DLG4	ENSECAP00000021772	ENSECAP00000047031	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.928
CDK5	LRP4	ENSECAP00000021772	ENSECAP00000021146	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	LDL receptor related protein 4.	0.452
COLQ	AGRN	ENSECAP00000017456	ENSECAP00000035833	Collagen like tail subunit of asymmetric acetylcholinesterase.	Agrin.	0.658
DLG1	DLG3	ENSECAP00000036397	ENSECAP00000034810	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.983
DLG1	DLG4	ENSECAP00000036397	ENSECAP00000047031	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.924
DLG1	ERBIN	ENSECAP00000036397	ENSECAP00000004178	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Erbb2 interacting protein.	0.433
DLG1	NLGN1	ENSECAP00000036397	ENSECAP00000046887	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Neuroligin 1.	0.407
DLG1	NLGN2	ENSECAP00000036397	ENSECAP00000014266	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Neuroligin 2.	0.404
DLG1	SCRIB	ENSECAP00000036397	ENSECAP00000053331	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Scribble planar cell polarity protein.	0.873
DLG1	SHANK3	ENSECAP00000036397	ENSECAP00000054772	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.590
DLG2	DLG3	ENSECAP00000048526	ENSECAP00000034810	Discs large MAGUK scaffold protein 2.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.842
DLG2	DLG4	ENSECAP00000048526	ENSECAP00000047031	Discs large MAGUK scaffold protein 2.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.925
DLG2	ERBIN	ENSECAP00000048526	ENSECAP00000004178	Discs large MAGUK scaffold protein 2.	Erbb2 interacting protein.	0.418
DLG2	NLGN1	ENSECAP00000048526	ENSECAP00000046887	Discs large MAGUK scaffold protein 2.	Neuroligin 1.	0.404
DLG2	NLGN2	ENSECAP00000048526	ENSECAP00000014266	Discs large MAGUK scaffold protein 2.	Neuroligin 2.	0.404
DLG2	SHANK3	ENSECAP00000048526	ENSECAP00000054772	Discs large MAGUK scaffold protein 2.	SH3 and multiple ankyrin repeat domains 3.	0.590
DLG3	DLG1	ENSECAP00000034810	ENSECAP00000036397	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.983