STRINGSTRING
SNX4 SNX4 PLA2G3 PLA2G3 SPHK2 SPHK2 FGR FGR IL4 IL4 VAMP7 VAMP7 VAMP8 VAMP8 IL13 IL13 SYK SYK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNX4Sorting nexin 4. (475 aa)
PLA2G3Phospholipase A2 group III. (513 aa)
SPHK2Sphingosine kinase 2. (654 aa)
FGRTyrosine-protein kinase. (527 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (139 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (276 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
IL13Interleukin-13. (133 aa)
SYKTyrosine-protein kinase. (716 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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