STRINGSTRING
SOX12 SOX12 CTLA4 CTLA4 BCL6 BCL6 DUSP10 DUSP10 TGFB1 TGFB1 DROSHA DROSHA LOC100147151 LOC100147151 IRF1 IRF1 VSIR VSIR FANCD2 FANCD2 FANCA FANCA FOXO3 FOXO3 KAT2A KAT2A SOCS1 SOCS1 KAT5 KAT5 IFNG IFNG AMBRA1 AMBRA1 ENSECAP00000033220 ENSECAP00000033220 LOC100146250 LOC100146250 FOXP3 FOXP3 LOC100053579 LOC100053579 IL2RG IL2RG LOC100630393 LOC100630393 LOC100063866 LOC100063866 CD28 CD28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX12Transcription factor SOX. (316 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
BCL6BCL6 transcription repressor. (699 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
DROSHADrosha ribonuclease III. (1374 aa)
LOC100147151Amine oxidase. (530 aa)
IRF1Interferon regulatory factor 1. (423 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
FANCD2FA complementation group D2. (1449 aa)
FANCAFA complementation group A. (1520 aa)
FOXO3Forkhead box O3. (671 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
SOCS1Suppressor of cytokine signaling 1. (222 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1299 aa)
ENSECAP00000033220AIG1-type G domain-containing protein. (267 aa)
LOC100146250AIG1-type G domain-containing protein. (315 aa)
FOXP3Forkhead box P3. (452 aa)
LOC100053579Ig-like domain-containing protein. (385 aa)
IL2RGFibronectin type-III domain-containing protein. (457 aa)
LOC100630393AIG1-type G domain-containing protein. (315 aa)
LOC100063866AIG1-type G domain-containing protein. (413 aa)
CD28CD28 molecule. (228 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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