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| MELTF | Melanotransferrin; Belongs to the transferrin family. (739 aa) | ||||
| CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) | ||||
| PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa) | ||||
| HIP1R | Huntingtin interacting protein 1 related. (1203 aa) | ||||
| FBXW9 | F-box and WD repeat domain containing 9. (477 aa) | ||||
| GRAMD4 | GRAM domain containing 4. (728 aa) | ||||
| FGFR4 | Fibroblast growth factor receptor. (855 aa) | ||||
| TNFRSF1B | TNF receptor superfamily member 1B. (481 aa) | ||||
| BCL2L11 | BCL2 like 11. (289 aa) | ||||
| DAPK1 | Death associated protein kinase 1. (1457 aa) | ||||
| NKD2 | NKD inhibitor of WNT signaling pathway 2. (553 aa) | ||||
| APH1B | Aph-1 homolog B, gamma-secretase subunit. (524 aa) | ||||
| ENSECAP00000051121 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
| NOP53 | NOP53 ribosome biogenesis factor. (549 aa) | ||||
| KCNE2 | Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa) | ||||
| LOC111775628 | Uncharacterized protein; Belongs to the peptidase C1 family. (428 aa) | ||||
| SH3D19 | SH3 domain containing 19. (1072 aa) | ||||
| WDR20 | WD repeat domain 20. (627 aa) | ||||
| DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (325 aa) | ||||
| BCAP31 | B cell receptor associated protein 31. (280 aa) | ||||
| RNF14 | RBR-type E3 ubiquitin transferase. (467 aa) | ||||
| DET1 | DET1 partner of COP1 E3 ubiquitin ligase. (709 aa) | ||||
| WDR48 | WD repeat domain 48. (796 aa) | ||||
| PSME1 | Proteasome activator subunit 1. (249 aa) | ||||
| RNF180 | Ring finger protein 180. (592 aa) | ||||
| CAPN9 | Calpain 9; Belongs to the peptidase C2 family. (712 aa) | ||||
| LOC100061631 | EF-hand domain-containing protein; Belongs to the S-100 family. (160 aa) | ||||
| PAWR | Uncharacterized protein. (596 aa) | ||||
| HIP1 | Huntingtin interacting protein 1. (1082 aa) | ||||
| DISC1 | DISC1 scaffold protein. (890 aa) | ||||
| RP1L1 | Uncharacterized protein. (387 aa) | ||||
| CCDC22 | Coiled-coil domain containing 22. (627 aa) | ||||
| NOD1 | Nucleotide binding oligomerization domain containing 1. (993 aa) | ||||
| NUB1 | Negative regulator of ubiquitin like proteins 1. (640 aa) | ||||
| LYN | Tyrosine-protein kinase. (533 aa) | ||||
| NCSTN | Nicastrin. (709 aa) | ||||
| PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) | ||||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain. (233 aa) | ||||
| CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
| AGBL4 | ATP/GTP binding protein like 4. (531 aa) | ||||
| ASPH | Aspartate beta-hydroxylase. (790 aa) | ||||
| GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (867 aa) | ||||
| SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
| HPN | Hepsin; Belongs to the peptidase S1 family. (513 aa) | ||||
| CASP8AP2 | Caspase 8 associated protein 2. (2070 aa) | ||||
| TMEM259 | Transmembrane protein 259. (635 aa) | ||||
| CASP9 | Caspase 9; Belongs to the peptidase C14A family. (632 aa) | ||||
| MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1362 aa) | ||||
| CCBE1 | Collagen and calcium binding EGF domains 1. (439 aa) | ||||
| AIM2 | Absent in melanoma 2. (352 aa) | ||||
| ADAM8 | Uncharacterized protein. (824 aa) | ||||
| FZR1 | Fizzy and cell division cycle 20 related 1. (695 aa) | ||||
| SYK | Tyrosine-protein kinase. (716 aa) | ||||
| DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (685 aa) | ||||
| MKRN2 | Makorin ring finger protein 2. (502 aa) | ||||
| ZYG11B | Zyg-11 family member B, cell cycle regulator. (760 aa) | ||||
| STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
| CTSH | Uncharacterized protein; Belongs to the peptidase C1 family. (386 aa) | ||||
| FBXW8 | F-box and WD repeat domain containing 8. (851 aa) | ||||
| EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (436 aa) | ||||
| NEK5 | NIMA related kinase 5. (812 aa) | ||||
| PSME4 | Proteasome activator subunit 4. (1864 aa) | ||||
| ZER1 | Zyg-11 related cell cycle regulator. (766 aa) | ||||
| PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) | ||||
| MAPK9 | Mitogen-activated protein kinase. (446 aa) | ||||
| PIAS1 | Protein inhibitor of activated STAT 1. (678 aa) | ||||
| PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (526 aa) | ||||
| DAB2 | DAB adaptor protein 2. (765 aa) | ||||
| ENSECAP00000034034 | Uncharacterized protein. (106 aa) | ||||
| CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) | ||||
| ENSECAP00000033783 | Uncharacterized protein. (78 aa) | ||||
| SENP1 | SUMO specific peptidase 1. (691 aa) | ||||
| RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (569 aa) | ||||
| PIDD1 | P53-induced death domain protein 1. (915 aa) | ||||
| AGTPBP1 | ATP/GTP binding protein 1. (1278 aa) | ||||
| APH1A | Aph-1 homolog A, gamma-secretase subunit. (274 aa) | ||||
| SIRT6 | Sirtuin 6. (407 aa) | ||||
| CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) | ||||
| IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
| RNF217 | RBR-type E3 ubiquitin transferase. (540 aa) | ||||
| RNF144A | RBR-type E3 ubiquitin transferase. (361 aa) | ||||
| SIRT1 | Sirtuin 1. (737 aa) | ||||
| SIRT2 | Sirtuin 2. (462 aa) | ||||
| DAP | Uncharacterized protein. (250 aa) | ||||
| OSBPL7 | Oxysterol binding protein like 7. (879 aa) | ||||
| FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) | ||||
| LOC100061598 | EF-hand domain-containing protein; Belongs to the S-100 family. (162 aa) | ||||
| BBS7 | Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa) | ||||
| PSME3 | Proteasome activator subunit 3. (265 aa) | ||||
| ARIH1 | RBR-type E3 ubiquitin transferase. (554 aa) | ||||
| NLRP6 | NLR family pyrin domain containing 6. (892 aa) | ||||
| BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) | ||||
| PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (531 aa) | ||||
| COP1 | COP1 E3 ubiquitin ligase. (737 aa) | ||||
| GSN | Gelsolin; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). (871 aa) | ||||
| CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) | ||||
| FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (753 aa) | ||||
| AURKAIP1 | Aurora kinase A interacting protein 1. (199 aa) | ||||
| RNF144B | RBR-type E3 ubiquitin transferase. (304 aa) | ||||
| ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1098 aa) | ||||
| S100A9 | EF-hand domain-containing protein; Belongs to the S-100 family. (153 aa) | ||||
| FOXL2 | Forkhead box L2. (378 aa) | ||||
| LOC102148739 | NACHT domain-containing protein. (1069 aa) | ||||
| SNX9 | Sorting nexin. (621 aa) | ||||
| BBC3 | BCL2 binding component 3. (261 aa) | ||||
| CBFA2T3 | CBFA2/RUNX1 translocation partner 3. (658 aa) | ||||
| PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (433 aa) | ||||
| DAB2IP | DAB2 interacting protein. (1166 aa) | ||||
| TANK | TRAF family member associated NFKB activator. (426 aa) | ||||
| TNFSF15 | Tumor necrosis factor ligand 1B. (260 aa) | ||||
| CLEC3B | C-type lectin domain family 3 member B. (262 aa) | ||||
| PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa) | ||||
| MTCH1 | Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (435 aa) | ||||
| PACSIN3 | Protein kinase C and casein kinase substrate in neurons 3. (428 aa) | ||||
| RNF185 | Ring finger protein 185. (192 aa) | ||||
| BCL10 | BCL10 immune signaling adaptor. (374 aa) | ||||
| CCN1 | Cellular communication network factor 1. (382 aa) | ||||
| GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa) | ||||
| PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (423 aa) | ||||
| RAD23A | RAD23 homolog A, nucleotide excision repair protein. (363 aa) | ||||
| SH3RF2 | SH3 domain containing ring finger 2. (732 aa) | ||||
| CASP10 | Caspase 10; Belongs to the peptidase C14A family. (478 aa) | ||||
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) | ||||
| BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
| AXIN1 | Axin 1. (939 aa) | ||||
| USP50 | Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (333 aa) | ||||
| F3 | Coagulation factor III, tissue factor. (388 aa) | ||||
| PRELID1 | PRELI domain containing 1. (219 aa) | ||||
| LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (486 aa) | ||||
| IST1 | IST1 factor associated with ESCRT-III. (363 aa) | ||||
| GBA | Glucosylceramidase. (536 aa) | ||||
| FBXW7 | F-box and WD repeat domain containing 7. (754 aa) | ||||
| REST | RE1 silencing transcription factor. (1039 aa) | ||||
| RACK1 | WD_REPEATS_REGION domain-containing protein. (317 aa) | ||||
| NRDC | Nardilysin convertase. (1247 aa) | ||||
| CLUL1 | Clusterin; Belongs to the clusterin family. (465 aa) | ||||
| TFAP4 | Transcription factor AP-4. (338 aa) | ||||
| MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (442 aa) | ||||
| LOC100055155 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa) | ||||
| PCOLCE | Procollagen C-endopeptidase enhancer. (459 aa) | ||||
| MYH9 | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa) | ||||
| SH3RF1 | SH3 domain containing ring finger 1. (886 aa) | ||||
| CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (510 aa) | ||||
| FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (212 aa) | ||||
| EFNA1 | Ephrin A1; Belongs to the ephrin family. (317 aa) | ||||
| PDCD6 | Programmed cell death 6. (189 aa) | ||||
| AGER | Advanced glycosylation end-product specific receptor. (403 aa) | ||||
| DVL1 | Dishevelled segment polarity protein 1. (700 aa) | ||||
| SPON1 | Spondin 1. (807 aa) | ||||
| PSMD10 | Proteasome 26S subunit, non-ATPase 10. (270 aa) | ||||
| PCOLCE2 | Procollagen C-endopeptidase enhancer 2. (414 aa) | ||||
| TMTC3 | Transmembrane O-mannosyltransferase targeting cadherins 3. (949 aa) | ||||
| SMAD7 | Mothers against decapentaplegic homolog. (426 aa) | ||||
| ZYG11A | Zyg-11 family member A, cell cycle regulator. (760 aa) | ||||
| FAM162A | Family with sequence similarity 162 member A. (155 aa) | ||||
| DDRGK1 | DDRGK domain containing 1. (315 aa) | ||||
| DIABLO | Diablo IAP-binding mitochondrial protein. (237 aa) | ||||
| ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa) | ||||
| CDC20 | Cell division cycle 20. (499 aa) | ||||
| NLRC4 | NLR family CARD domain containing 4. (1053 aa) | ||||
| GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa) | ||||
| TRIB1 | Tribbles pseudokinase 1. (386 aa) | ||||
| CARD9 | Caspase recruitment domain family member 9. (537 aa) | ||||
| SH3RF3 | SH3 domain containing ring finger 3. (879 aa) | ||||
| S100A10 | S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa) | ||||
| PDCD5 | Programmed cell death 5. (125 aa) | ||||
| PRICKLE1 | Prickle planar cell polarity protein 1. (832 aa) | ||||
| CNTN2 | Contactin 2. (1040 aa) | ||||
| TBC1D10A | TBC1 domain family member 10A. (509 aa) | ||||
| GRN | Antimicrobial peptide eNAP-1; Has antimicrobial activity against Gram-negative and Gram- positive bacteria; Belongs to the granulin family. (587 aa) | ||||
| PSME2 | Proteasome activator subunit 2. (239 aa) | ||||
| AXIN2 | Axin 2. (843 aa) | ||||
| YJEFN3 | YjeF N-terminal domain-containing protein. (249 aa) | ||||
| VSIR | V-set immunoregulatory receptor. (311 aa) | ||||
| PLK1 | Serine/threonine-protein kinase PLK. (604 aa) | ||||
| RNFT2 | Ring finger protein, transmembrane 2. (309 aa) | ||||
| SMURF1 | E3 ubiquitin-protein ligase. (757 aa) | ||||
| NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) | ||||
| NGFR | Nerve growth factor receptor. (435 aa) | ||||
| ECSCR | Uncharacterized protein. (317 aa) | ||||
| NLRP12 | NLR family pyrin domain containing 12. (1061 aa) | ||||
| RNFT1 | RING-type domain-containing protein. (433 aa) | ||||
| PRR7 | Proline rich 7, synaptic. (274 aa) | ||||
| ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (274 aa) | ||||
| CLN6 | CLN6 transmembrane ER protein. (371 aa) | ||||
| SFRP2 | Secreted frizzled related protein 2. (294 aa) | ||||
| NODAL | Nodal growth differentiation factor. (348 aa) | ||||
| DMWD | DM1 locus, WD repeat containing. (745 aa) | ||||
| CDC20B | Cell division cycle 20B. (515 aa) | ||||
| PDCD2 | Programmed cell death 2. (344 aa) | ||||
| BAX | BCL2 associated X, apoptosis regulator. (192 aa) | ||||
| FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (283 aa) | ||||
| UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1416 aa) | ||||
| PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (448 aa) | ||||
| CLPX | Caseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa) | ||||
| RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) | ||||
| ANGPTL8 | Angiopoietin like 8. (198 aa) | ||||
| MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (422 aa) | ||||
| SNX33 | Sorting nexin. (574 aa) | ||||
| NLRP3 | NLR family pyrin domain containing 3. (1031 aa) | ||||
| TREM2 | Triggering receptor expressed on myeloid cells 2. (298 aa) | ||||
| USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa) | ||||
| BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
| NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) | ||||
| STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) | ||||
| TNP1 | Transition protein 1. (55 aa) | ||||
| CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
| BAG6 | BCL2 associated athanogene 6. (1073 aa) | ||||
| EPHA4 | EPH receptor A4. (949 aa) | ||||
| RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) | ||||
| FAS | Fas cell surface death receptor. (365 aa) | ||||
| MALT1 | MALT1 paracaspase. (850 aa) | ||||
| PLGRKT | Plasminogen receptor with a C-terminal lysine. (380 aa) | ||||
| BAG2 | BCL2 associated athanogene 2. (211 aa) | ||||
| RNF19B | RBR-type E3 ubiquitin transferase. (549 aa) | ||||
| SRC | Tyrosine-protein kinase. (551 aa) | ||||
| DDA1 | DET1 and DDB1 associated 1. (102 aa) | ||||
| ATP5IF1 | ATP synthase inhibitory factor subunit 1. (108 aa) | ||||
| IFT57 | Intraflagellar transport 57. (429 aa) | ||||
| HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (392 aa) | ||||
| ASTL | Metalloendopeptidase. (429 aa) | ||||
| TNIP1 | TNFAIP3 interacting protein 1. (723 aa) | ||||
| ARIH2 | RBR-type E3 ubiquitin transferase. (491 aa) | ||||
| LRRK2 | Leucine rich repeat kinase 2. (2528 aa) | ||||
| F12 | Coagulation factor XII. (615 aa) | ||||
| F7DPV9_HORSE | Uncharacterized protein. (145 aa) | ||||
| LGMN | Legumain. (433 aa) | ||||
| ANKIB1 | RBR-type E3 ubiquitin transferase. (1103 aa) | ||||
| CIDEB | Cell death inducing DFFA like effector b. (222 aa) | ||||
| S100A8 | Protein S100; Belongs to the S-100 family. (89 aa) | ||||
| RCN3 | Reticulocalbin 3. (328 aa) | ||||
| TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
| SGTA | Small glutamine rich tetratricopeptide repeat containing alpha. (313 aa) | ||||
| P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) | ||||
| CSNK1D | Casein kinase 1 delta; Belongs to the protein kinase superfamily. (428 aa) | ||||
| PYCARD | PYD and CARD domain containing. (195 aa) | ||||
| TMEM130 | Transmembrane protein 130. (435 aa) | ||||
| ZC3H12A | Zinc finger CCCH-type containing 12A. (615 aa) | ||||
| TRIM32 | Tripartite motif containing 32. (653 aa) | ||||
| RNF139 | Ring finger protein 139. (665 aa) | ||||
| NLRP1 | NLR family pyrin domain containing 1. (1448 aa) | ||||
| F6WH02_HORSE | FIST_C domain-containing protein. (381 aa) | ||||
| HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (215 aa) | ||||
| RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) | ||||
| RHBDD1 | Rhomboid domain containing 1. (316 aa) | ||||
| F7CJH7_HORSE | RING-type domain-containing protein. (433 aa) | ||||
| PSENEN | Presenilin enhancer, gamma-secretase subunit. (101 aa) | ||||
| TRIM67 | Tripartite motif containing 67. (783 aa) | ||||
| TTBK1 | Tau tubulin kinase 1. (1409 aa) | ||||
| CLU | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (450 aa) | ||||
| FN1 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2477 aa) | ||||
| MEFV | MEFV innate immuity regulator, pyrin. (117 aa) | ||||
| FBXO22 | FIST_C domain-containing protein. (404 aa) | ||||
| BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa) | ||||
| CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) | ||||
| USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa) | ||||
| PML | Promyelocytic leukemia. (881 aa) | ||||
| CASP8 | Caspase 8; Belongs to the peptidase C14A family. (464 aa) | ||||
| EGLN3 | Egl-9 family hypoxia inducible factor 3. (239 aa) | ||||
| F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa) | ||||
| SOCS4 | Suppressor of cytokine signaling 4. (441 aa) | ||||
| AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) | ||||
| ADRA2A | Adrenoceptor alpha 2A. (465 aa) | ||||
| PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) | ||||
| FAM122A | Family with sequence similarity 122A. (329 aa) | ||||
| TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) | ||||
| NKX3-1 | NK3 homeobox 1. (240 aa) | ||||
| GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa) | ||||
| LAPTM5 | Lysosomal protein transmembrane 5. (288 aa) | ||||
| HTRA2 | HtrA serine peptidase 2. (458 aa) | ||||
| SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (962 aa) | ||||
| TRIB3 | Tribbles pseudokinase 3. (353 aa) | ||||
| FGL2 | Fibrinogen like 2. (479 aa) | ||||
| BOK | BCL2 family apoptosis regulator BOK. (213 aa) | ||||