STRINGSTRING
WNT1 WNT1 INSR INSR RACGAP1 RACGAP1 ZZZ3 ZZZ3 SGF29 SGF29 JAG1 JAG1 BAG6 BAG6 DLL1 DLL1 PAFAH1B1 PAFAH1B1 INO80E INO80E INO80D INO80D NODAL NODAL SFRP2 SFRP2 RUVBL2 RUVBL2 KAT14 KAT14 TFPT TFPT TADA3 TADA3 LAMA4 LAMA4 EHMT1 EHMT1 NIPBL NIPBL CFL1 CFL1 CRB2 CRB2 B4GALT5 B4GALT5 RACK1 RACK1 NOTCH1 NOTCH1 INO80 INO80 NLRP5 NLRP5 PHLDB1 PHLDB1 WNT2 WNT2 KAT2A KAT2A DHX36 DHX36 TADA2A TADA2A LAMA2 LAMA2 HES1 HES1 OSR1 OSR1 MBIP MBIP TENM4 TENM4 MCRS1 MCRS1 NOCT NOCT PHLDB3 PHLDB3 WDR5 WDR5 POGLUT1 POGLUT1 SEPTIN7 SEPTIN7 SOX17 SOX17 AMOT AMOT ACTR8 ACTR8 LAMA1 LAMA1 RAB14 RAB14 PHLDB2 PHLDB2 RBM19 RBM19 HNF4A HNF4A NFE2L2 NFE2L2 UCHL5 UCHL5 TRIP12 TRIP12 RUVBL1 RUVBL1 LHX1 LHX1 NR2C2 NR2C2 WNT2B WNT2B NFRKB NFRKB PHLDA2 PHLDA2 HESX1 HESX1 YEATS2 YEATS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
RACGAP1Rac GTPase activating protein 1. (653 aa)
ZZZ3Zinc finger ZZ-type containing 3. (903 aa)
SGF29SAGA complex associated factor 29. (309 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
BAG6BCL2 associated athanogene 6. (1073 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
INO80EINO80 complex subunit E. (244 aa)
INO80DINO80 complex subunit D. (1026 aa)
NODALNodal growth differentiation factor. (348 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
KAT14Lysine acetyltransferase 14. (780 aa)
TFPTTCF3 fusion partner. (253 aa)
TADA3Transcriptional adaptor 3. (432 aa)
LAMA4Laminin subunit alpha 4. (1824 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1296 aa)
NIPBLNipped-B protein. (2805 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
CRB2Crumbs cell polarity complex component 2. (1286 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (317 aa)
NOTCH1Notch receptor 1. (2581 aa)
INO80INO80 complex ATPase subunit. (1561 aa)
NLRP5NLR family pyrin domain containing 5. (1100 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1753 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
DHX36DEAH-box helicase 36. (1029 aa)
TADA2ATranscriptional adapter. (443 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
OSR1Odd-skipped related transcription factor 1. (279 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
TENM4Teneurin transmembrane protein 4. (2866 aa)
MCRS1Microspherule protein 1. (539 aa)
NOCTNocturnin. (431 aa)
PHLDB3Pleckstrin homology like domain family B member 3. (764 aa)
WDR5WD repeat domain 5. (342 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (449 aa)
SOX17SRY-box transcription factor 17. (406 aa)
AMOTAngiomotin. (1089 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
LAMA1Laminin subunit alpha 1. (3127 aa)
RAB14RAB14, member RAS oncogene family. (260 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1340 aa)
RBM19RNA binding motif protein 19. (1185 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (605 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
TRIP12Thyroid hormone receptor interactor 12. (2040 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (485 aa)
LHX1LIM homeobox 1. (405 aa)
NR2C2Nuclear receptor subfamily 2 group C member 2. (629 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
NFRKBNuclear factor related to kappaB binding protein. (1309 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (157 aa)
HESX1HESX homeobox 1. (185 aa)
YEATS2YEATS domain containing 2. (1414 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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