STRINGSTRING
F6S0H6_HORSE F6S0H6_HORSE CALB1 CALB1 EN1 EN1 ATAD1 ATAD1 CAMK2N1 CAMK2N1 UCN UCN KLK8 KLK8 LOC111769342 LOC111769342 TBR1 TBR1 FOXO6 FOXO6 NDRG4 NDRG4 POMK POMK RTL4 RTL4 CHD7 CHD7 FOXB1 FOXB1 TIFAB TIFAB RIC8A RIC8A CHRM1 CHRM1 C5AR1 C5AR1 SYNJ1 SYNJ1 GABRA5 GABRA5 TTC36 TTC36 RAPGEF3 RAPGEF3 TTBK1 TTBK1 DNAH11 DNAH11 GIP GIP SORCS3 SORCS3 NTF4 NTF4 SLC8A2 SLC8A2 GPR155 GPR155 SRF SRF GIT1 GIT1 PTCHD1 PTCHD1 NF1 NF1 HTT HTT EP300 EP300 TSC1 TSC1 CHMP2B CHMP2B NGF NGF LGMN LGMN PRRT1 PRRT1 NFATC4 NFATC4 ADGRF1 ADGRF1 SLC1A4 SLC1A4 PTPRZ1 PTPRZ1 PRKAR2B PRKAR2B PAIP2 PAIP2 JPH4 JPH4 NPTX2 NPTX2 S100B S100B VDAC1 VDAC1 CCND2 CCND2 GTF2A1L GTF2A1L AAAS AAAS VIP VIP NPAS4 NPAS4 CREB1 CREB1 MFSD2A MFSD2A GATM GATM NETO1 NETO1 TACO1 TACO1 PAFAH1B1 PAFAH1B1 BRINP1 BRINP1 TREM2 TREM2 CHRNA4 CHRNA4 CAMK4 CAMK4 BTG2 BTG2 MAPK8IP2 MAPK8IP2 METTL23 METTL23 PAK6 PAK6 PTRHD1 PTRHD1 CHST10 CHST10 CLN3 CLN3 ZZEF1 ZZEF1 BTBD9 BTBD9 JPH3 JPH3 CNTN2 CNTN2 LINS1 LINS1 GRM5 GRM5 TNR TNR NIPBL NIPBL KRAS KRAS SLC12A5 SLC12A5 SYT11 SYT11 DBH DBH PPP1R1B PPP1R1B LRRN4 LRRN4 GM2A GM2A AGER AGER NLGN3 NLGN3 PLCB1 PLCB1 SHROOM4 SHROOM4 RELN RELN APP APP NRGN NRGN SNAP25 SNAP25 JAKMIP1 JAKMIP1 ATP8A1 ATP8A1 TMPRSS11E TMPRSS11E B4GALT2 B4GALT2 CTNS CTNS CDK5 CDK5 NTF3 NTF3 ADCY8 ADCY8 C6H12orf57 C6H12orf57 CSMD1 CSMD1 ADCY1 ADCY1 KAT2A KAT2A SPG11 SPG11 RGS14 RGS14 MGAT3 MGAT3 LOC100060521 LOC100060521 DGKI DGKI LOC111769342-2 LOC111769342-2 C1QL1 C1QL1 MEF2C MEF2C CYFIP1 CYFIP1 PAK5 PAK5 PTN PTN GPR88 GPR88 SLC6A1 SLC6A1 ADCY3 ADCY3 BRAF BRAF DNAAF4 DNAAF4 DDHD2 DDHD2 NTRK2 NTRK2 JAKMIP2 JAKMIP2 SGCA SGCA PTCHD4 PTCHD4 NEUROG1 NEUROG1 SOBP SOBP SETD5 SETD5 BDNF BDNF TANC1 TANC1 SLC7A11 SLC7A11 SHISA7 SHISA7 ATXN1L ATXN1L ENSECAP00000039029 ENSECAP00000039029 JAKMIP3 JAKMIP3 CD164 CD164 ARC ARC ZNF385A ZNF385A ENSECAP00000041377 ENSECAP00000041377 NCSTN NCSTN SYNGAP1 SYNGAP1 CHL1 CHL1 HMGCR HMGCR NPS NPS DGCR2 DGCR2 CIC CIC IFT20 IFT20 NEDD9 NEDD9 CUX2 CUX2 STRA6 STRA6 GRIA1 GRIA1 ITGB1 ITGB1 TUSC3 TUSC3 GRIN2A GRIN2A MECP2 MECP2 ITGA5 ITGA5 CSMD2 CSMD2 HIF1A HIF1A ENSECAP00000049244 ENSECAP00000049244 UBA6 UBA6 ELAVL4 ELAVL4 SHANK2 SHANK2 CRTC1 CRTC1 LDLR LDLR LOC100051785 LOC100051785 LOC100147550 LOC100147550 SHANK1 SHANK1 PRKN PRKN SHANK3 SHANK3 ST3GAL4 ST3GAL4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6S0H6_HORSEUncharacterized protein. (134 aa)
CALB1Calbindin 1. (261 aa)
EN1Homeobox protein engrailed-like. (393 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
CAMK2N1Calcium/calmodulin dependent protein kinase II inhibitor 1. (78 aa)
UCNUrocortin. (126 aa)
KLK8Kallikrein related peptidase 8; Belongs to the peptidase S1 family. (262 aa)
LOC111769342Uncharacterized protein. (216 aa)
TBR1T-box brain transcription factor 1. (682 aa)
FOXO6Forkhead box O6. (366 aa)
NDRG4NDRG family member 4. (504 aa)
POMKProtein O-mannose kinase. (350 aa)
RTL4Retrotransposon Gag like 4. (304 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
FOXB1Forkhead box B1. (325 aa)
TIFABTIFA inhibitor. (162 aa)
RIC8ARIC8 guanine nucleotide exchange factor A. (530 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (374 aa)
SYNJ1Synaptojanin 1. (1579 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
TTC36Tetratricopeptide repeat domain 36. (188 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
TTBK1Tau tubulin kinase 1. (1409 aa)
DNAH11Dynein axonemal heavy chain 11. (4525 aa)
GIPGastric inhibitory polypeptide. (145 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1220 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
GPR155G protein-coupled receptor 155. (867 aa)
SRFSerum response factor. (512 aa)
GIT1GIT ArfGAP 1. (770 aa)
PTCHD1Patched domain containing 1. (888 aa)
NF1Neurofibromin 1. (3024 aa)
HTTHuntingtin. (3126 aa)
EP300E1A binding protein p300. (2430 aa)
TSC1TSC complex subunit 1. (1232 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (294 aa)
LGMNLegumain. (433 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
NFATC4Nuclear factor of activated T cells 4. (932 aa)
ADGRF1Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (956 aa)
SLC1A4Solute carrier family 1 member 4. (532 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2327 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (419 aa)
PAIP2Poly(A) binding protein interacting protein 2. (126 aa)
JPH4Junctophilin 4. (604 aa)
NPTX2Neuronal pentraxin 2. (430 aa)
S100BProtein S100; Belongs to the S-100 family. (93 aa)
VDAC1Voltage dependent anion channel 1. (364 aa)
CCND2Cyclin D2; Belongs to the cyclin family. (289 aa)
GTF2A1LUncharacterized protein. (473 aa)
AAASAladin WD repeat nucleoporin. (545 aa)
VIPVasoactive intestinal peptide. (171 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (529 aa)
GATMGlycine amidinotransferase. (473 aa)
NETO1Neuropilin and tolloid like 1. (662 aa)
TACO1Translational activator of cytochrome c oxidase I. (297 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (298 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (680 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
BTG2BTG anti-proliferation factor 2. (150 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (826 aa)
METTL23Methyltransferase like 23. (190 aa)
PAK6Non-specific serine/threonine protein kinase. (680 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
CHST10Carbohydrate sulfotransferase. (381 aa)
CLN3Battenin. (437 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2968 aa)
BTBD9BTB domain containing 9. (612 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (754 aa)
CNTN2Contactin 2. (1040 aa)
LINS1Lines homolog 1. (758 aa)
GRM5Glutamate metabotropic receptor 5. (1193 aa)
TNRTenascin R. (1358 aa)
NIPBLNipped-B protein. (2805 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
SLC12A5Solute carrier family 12 member 5. (1168 aa)
SYT11Synaptotagmin 11. (441 aa)
DBHSoluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline. Belongs to the copper type II ascorbate-dependent monooxygenase family. (610 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (205 aa)
LRRN4Leucine rich repeat neuronal 4. (739 aa)
GM2AGM2 ganglioside activator. (193 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
NLGN3Neuroligin 3. (848 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
SHROOM4Shroom family member 4. (1557 aa)
RELNReelin. (3460 aa)
APPAmyloid beta precursor protein. (811 aa)
NRGNNeurogranin. (78 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
JAKMIP1Janus kinase and microtubule interacting protein 1. (831 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1163 aa)
TMPRSS11ETransmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)
B4GALT2Beta-1,4-galactosyltransferase 2. (390 aa)
CTNSCystinosin, lysosomal cystine transporter. (397 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
C6H12orf57Chromosome 6 C12orf57 homolog. (126 aa)
CSMD1CUB and Sushi multiple domains 1. (3564 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2445 aa)
RGS14Regulator of G protein signaling 14. (568 aa)
MGAT3Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase. (505 aa)
LOC100060521Uncharacterized protein. (510 aa)
DGKIDiacylglycerol kinase. (1078 aa)
LOC111769342-2Patched domain-containing protein 4-like. (216 aa)
C1QL1Complement C1q like 1. (258 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1225 aa)
PAK5Non-specific serine/threonine protein kinase. (718 aa)
PTNPleiotrophin. (192 aa)
GPR88G protein-coupled receptor 88. (384 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (631 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (793 aa)
DNAAF4Dynein axonemal assembly factor 4. (437 aa)
DDHD2DDHD domain containing 2. (715 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
JAKMIP2Janus kinase and microtubule interacting protein 2. (841 aa)
SGCAIntegrin subunit alpha 3; Belongs to the integrin alpha chain family. (1075 aa)
PTCHD4Patched domain containing 4. (904 aa)
NEUROG1Neurogenin 1. (347 aa)
SOBPSine oculis binding protein homolog. (870 aa)
SETD5SET domain containing 5. (1478 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (299 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1966 aa)
SLC7A11Solute carrier family 7 member 11. (529 aa)
SHISA7Shisa family member 7. (564 aa)
ATXN1LAtaxin 1 like. (645 aa)
ENSECAP00000039029Uncharacterized protein. (188 aa)
JAKMIP3Janus kinase and microtubule interacting protein 3. (844 aa)
CD164CD164 molecule. (200 aa)
ARCActivity regulated cytoskeleton associated protein. (398 aa)
ZNF385AZinc finger protein 385A. (435 aa)
ENSECAP00000041377Uncharacterized protein. (132 aa)
NCSTNNicastrin. (709 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1349 aa)
CHL1Cell adhesion molecule L1 like. (1225 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (901 aa)
NPSNeuropeptide S. (129 aa)
DGCR2DiGeorge syndrome critical region gene 2. (550 aa)
CICCapicua transcriptional repressor. (2552 aa)
IFT20Intraflagellar transport 20. (157 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
CUX2Homeobox protein cut-like. (1502 aa)
STRA6Stimulated by retinoic acid 6. (711 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (808 aa)
TUSC3Tumor suppressor candidate 3. (348 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1452 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1248 aa)
CSMD2CUB and Sushi multiple domains 2. (3633 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (844 aa)
ENSECAP00000049244Uncharacterized protein. (631 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1052 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1850 aa)
CRTC1CREB regulated transcription coactivator 1. (781 aa)
LDLRLow density lipoprotein receptor. (937 aa)
LOC100051785Uncharacterized protein. (188 aa)
LOC100147550Uncharacterized protein. (235 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2170 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1807 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (402 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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