STRINGSTRING
OCA2 OCA2 KIT KIT ENPP1 ENPP1 AP3D1 AP3D1 ADAMTSL4 ADAMTSL4 ANKRD27 ANKRD27 ADAMTS20 ADAMTS20 RAB32 RAB32 SOX10 SOX10 AP1M1 AP1M1 SLC24A5 SLC24A5 MEF2C MEF2C LOC111767897 LOC111767897 ENSECAP00000032857 ENSECAP00000032857 EDNRB EDNRB LOC100060806 LOC100060806 RAB38 RAB38 HPS1 HPS1 HPS6 HPS6 TYRP1 TYRP1 GLI3 GLI3 LRMDA LRMDA MITF MITF BLOC1S5 BLOC1S5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OCA2OCA2 melanosomal transmembrane protein. (838 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1043 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1211 aa)
ADAMTSL4ADAMTS like 4. (1313 aa)
ANKRD27Ankyrin repeat domain 27. (1074 aa)
ADAMTS20ADAM metallopeptidase with thrombospondin type 1 motif 20. (1915 aa)
RAB32RAB32, member RAS oncogene family. (313 aa)
SOX10SRY-box transcription factor 10. (546 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (536 aa)
SLC24A5Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (501 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
LOC111767897Sodium/potassium/calcium exchanger 5. (501 aa)
ENSECAP00000032857Uncharacterized protein. (46 aa)
EDNRBEndothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. (447 aa)
LOC100060806Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
RAB38RAB38, member RAS oncogene family. (387 aa)
HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (735 aa)
HPS6Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (803 aa)
TYRP1Tyrosinase related protein 1. (543 aa)
GLI3GLI family zinc finger 3. (1581 aa)
LRMDALeucine rich melanocyte differentiation associated. (226 aa)
MITFMelanocyte inducing transcription factor. (641 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (188 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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