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ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) | ||||
PPARGC1A | PPARG coactivator 1 alpha. (839 aa) | ||||
TCF3 | Transcription factor 3. (679 aa) | ||||
ENSECAP00000036607 | B30.2/SPRY domain-containing protein. (208 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) | ||||
LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa) | ||||
LOC100069440 | Uncharacterized protein. (298 aa) | ||||
ADAM8 | Uncharacterized protein. (824 aa) | ||||
AIM2 | Absent in melanoma 2. (352 aa) | ||||
FANK1 | Fibronectin type III and ankyrin repeat domains 1. (401 aa) | ||||
ENSECAP00000039988 | Prohibitin. (299 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
ENSECAP00000041316 | Uncharacterized protein. (498 aa) | ||||
CTH | Cystathionine gamma-lyase. (409 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
TRIM27 | Tripartite motif containing 27. (536 aa) | ||||
NOD1 | Nucleotide binding oligomerization domain containing 1. (993 aa) | ||||
CAT | Catalase. (598 aa) | ||||
SPHK1 | Sphingosine kinase 1. (459 aa) | ||||
CAPN9 | Calpain 9; Belongs to the peptidase C2 family. (712 aa) | ||||
TAF12 | TATA-box binding protein associated factor 12. (322 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (805 aa) | ||||
FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
MAVS | Mitochondrial antiviral signaling protein. (597 aa) | ||||
TRAF1 | TNF receptor-associated factor. (415 aa) | ||||
KDM1A | Lysine demethylase 1A. (1007 aa) | ||||
RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (535 aa) | ||||
TRIM25 | Tripartite motif containing 25. (643 aa) | ||||
CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) | ||||
ENSECAP00000051121 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
TNFRSF11A | TNF receptor superfamily member 11a. (647 aa) | ||||
HIPK2 | Homeodomain interacting protein kinase 2. (1244 aa) | ||||
MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) | ||||
NOLC1 | PPARG related coactivator 1. (1679 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (448 aa) | ||||
NFAM1 | NFAT activating protein with ITAM motif 1. (255 aa) | ||||
EP300 | E1A binding protein p300. (2430 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
AR | Androgen receptor. (882 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) | ||||
DHX33 | DEAH-box helicase 33. (706 aa) | ||||
TERF2IP | TERF2 interacting protein. (387 aa) | ||||
NTS | Neurotensin. (170 aa) | ||||
TRIM13 | Tripartite motif containing 13. (409 aa) | ||||
ADGRF1 | Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (956 aa) | ||||
EDN1 | Endothelin 1. (202 aa) | ||||
TRIML1 | Tripartite motif family like 1. (462 aa) | ||||
BTNL9 | Butyrophilin like 9. (545 aa) | ||||
UBE2V1 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) | ||||
MID2 | Midline 2. (735 aa) | ||||
FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa) | ||||
TRIML2 | Tripartite motif family like 2. (427 aa) | ||||
IRAK2 | Interleukin 1 receptor associated kinase 2. (621 aa) | ||||
RGCC | Regulator of cell cycle. (155 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) | ||||
KIT | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (312 aa) | ||||
MALT1 | MALT1 paracaspase. (850 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) | ||||
PRKCH | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
COPS5 | COP9 signalosome complex subunit 5-like protein. (334 aa) | ||||
TLR9 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa) | ||||
F7CNV6_HORSE | Uncharacterized protein. (1071 aa) | ||||
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1176 aa) | ||||
TRIM15 | Tripartite motif containing 15. (458 aa) | ||||
JMY | Junction mediating and regulatory protein, p53 cofactor. (993 aa) | ||||
TRIM34 | Uncharacterized protein. (496 aa) | ||||
HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (498 aa) | ||||
DHX9 | DExH-box helicase 9. (1284 aa) | ||||
ABRA | Actin binding Rho activating protein. (381 aa) | ||||
TSSK4 | Testis specific serine kinase 4. (337 aa) | ||||
TNFSF11 | Tumor necrosis factor ligand superfamily member. (318 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (231 aa) | ||||
IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) | ||||
TRIM8 | Tripartite motif containing 8. (551 aa) | ||||
NODAL | Nodal growth differentiation factor. (348 aa) | ||||
TRIM26 | Tripartite motif containing 26. (539 aa) | ||||
PHB2 | Prohibitin. (299 aa) | ||||
PARK7 | Parkinsonism associated deglycase. (268 aa) | ||||
PRDX3 | Peroxiredoxin 3. (374 aa) | ||||
CD40 | Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). (280 aa) | ||||
TRIM14 | Tripartite motif containing 14. (440 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1013 aa) | ||||
CRNN | Cornulin. (480 aa) | ||||
FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) | ||||
CIB1 | Calcium and integrin binding 1. (191 aa) | ||||
ANXA3 | Annexin. (323 aa) | ||||
NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa) | ||||
CARD9 | Caspase recruitment domain family member 9. (537 aa) | ||||
NLRC4 | NLR family CARD domain containing 4. (1053 aa) | ||||
PPARGC1B | PPARG coactivator 1 beta. (1239 aa) | ||||
ARID5B | AT-rich interaction domain 5B. (1109 aa) | ||||
DDRGK1 | DDRGK domain containing 1. (315 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) | ||||
SAV1 | Salvador family WW domain containing protein 1. (384 aa) | ||||
CYTL1 | Cytokine like 1. (136 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (403 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (397 aa) | ||||
RELN | Reelin. (3460 aa) | ||||
ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1687 aa) | ||||
TRIM62 | Tripartite motif containing 62. (475 aa) | ||||
APP | Amyloid beta precursor protein. (811 aa) | ||||
HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1117 aa) | ||||
DDX58 | DExD/H-box helicase 58. (1021 aa) | ||||
FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) | ||||
CLUL1 | Clusterin; Belongs to the clusterin family. (465 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (251 aa) | ||||
ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (608 aa) | ||||
CRTC2 | CREB regulated transcription coactivator 2. (684 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (799 aa) | ||||
BUD31 | BUD31 homolog. (144 aa) | ||||
TRAPPC9 | Trafficking protein particle complex 9. (1180 aa) | ||||
MTPN | Myotrophin. (118 aa) | ||||
TRIM38 | Tripartite motif containing 38. (464 aa) | ||||
TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (767 aa) | ||||
CRTC3 | CREB regulated transcription coactivator 3. (619 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) | ||||
ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa) | ||||
WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) | ||||
ESR2 | Estrogen receptor 2. (550 aa) | ||||
BCL10 | BCL10 immune signaling adaptor. (374 aa) | ||||
ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa) | ||||
MYOCD | Myocardin. (987 aa) | ||||
IRAK3 | Interleukin 1 receptor associated kinase 3. (614 aa) | ||||
EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (388 aa) | ||||
FOXA1 | Forkhead box A1. (504 aa) | ||||
TRIM37 | Tripartite motif containing 37. (1093 aa) | ||||
RAB7B | RAB7B, member RAS oncogene family. (308 aa) | ||||
TRIM6 | Uncharacterized protein. (490 aa) | ||||
STK3 | Serine/threonine kinase 3. (574 aa) | ||||
TFDP1 | Transcription factor. (410 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (822 aa) | ||||
LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (371 aa) | ||||
RIPK4 | Receptor interacting serine/threonine kinase 4. (785 aa) | ||||
STING1 | Transmembrane protein 173. (405 aa) | ||||
STK36 | Serine/threonine kinase 36. (1349 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (655 aa) | ||||
CAMK1D | Calcium/calmodulin dependent protein kinase ID. (395 aa) | ||||
MTDH | Metadherin. (615 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa) | ||||
ZBTB7A | Zinc finger and BTB domain containing 7A. (794 aa) | ||||
PLPP3 | Phospholipid phosphatase 3. (312 aa) | ||||
ATF2 | Activating transcription factor 2. (512 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (770 aa) | ||||
ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1120 aa) | ||||
PINK1 | PTEN induced kinase 1. (585 aa) | ||||
TRIM32 | Tripartite motif containing 32. (653 aa) | ||||
SRF | Serum response factor. (512 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (249 aa) | ||||
RNF25 | Ring finger protein 25. (459 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
RIPK3 | Receptor interacting serine/threonine kinase 3. (513 aa) | ||||
CSF3 | Colony stimulating factor 3. (204 aa) | ||||
TRIM68 | Tripartite motif containing 68. (484 aa) | ||||
LOC100060051 | Uncharacterized protein. (603 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) | ||||
CARD14 | Caspase recruitment domain family member 14. (1003 aa) | ||||
TRIM41 | Tripartite motif containing 41. (631 aa) | ||||
CLU | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] (450 aa) | ||||
ZC4H2 | Zinc finger C4H2-type containing. (272 aa) | ||||
CRTC1 | CREB regulated transcription coactivator 1. (781 aa) | ||||
CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) | ||||
LRP8 | LDL receptor related protein 8. (1011 aa) | ||||
JUP | Junction plakoglobin. (960 aa) | ||||
FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (836 aa) | ||||
EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (540 aa) | ||||
IL18RAP | Interleukin 18 receptor accessory protein. (600 aa) | ||||
RTKN2 | Rhotekin 2. (608 aa) | ||||
MBTPS2 | Membrane bound transcription factor peptidase, site 2. (531 aa) | ||||
FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (595 aa) | ||||
NKX3-1 | NK3 homeobox 1. (240 aa) | ||||
HSF1 | Heat shock transcription factor 1. (535 aa) | ||||
TRIM52 | Tripartite motif containing 52. (286 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
GREM1 | Gremlin 1, DAN family BMP antagonist. (143 aa) | ||||
RHEBL1 | RHEB like 1. (183 aa) | ||||
DVL2 | Dishevelled segment polarity protein 2. (737 aa) | ||||
RNF220 | Ring finger protein 220. (566 aa) | ||||
IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) | ||||
TRIM22 | Tripartite motif containing 22. (498 aa) | ||||
THAP11 | THAP domain containing 11. (308 aa) | ||||
LOC100054534 | Uncharacterized protein. (511 aa) | ||||
TRIM21 | Tripartite motif containing 21. (469 aa) | ||||
CARD11 | Caspase recruitment domain family member 11. (1156 aa) | ||||
TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) | ||||
PLCG2 | Phosphoinositide phospholipase C. (1331 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (979 aa) | ||||
DDR2 | Discoidin domain receptor tyrosine kinase 2. (855 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
SLCO3A1 | Solute carrier organic anion transporter family member. (710 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (569 aa) | ||||
LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (715 aa) | ||||
ANKRD42 | Ankyrin repeat domain 42. (599 aa) | ||||
IL18R1 | Interleukin 18 receptor 1. (826 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (880 aa) | ||||
NEUROG1 | Neurogenin 1. (347 aa) | ||||
PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (811 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (717 aa) |