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| | EIF3D | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa) |
| | MAPRE3 | Uncharacterized protein. (281 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (318 aa) |
| | C2H4orf3 | Chromosome 2 C4orf3 homolog. (68 aa) |
| | TFIP11 | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa) |
| | MITD1 | Microtubule interacting and trafficking domain containing 1. (346 aa) |
| | VTN | Vitronectin. (478 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (377 aa) |
| | DHX9 | DExH-box helicase 9. (1284 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (406 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (573 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | LOX | Lysyl oxidase. (481 aa) |
| | NVL | Nuclear VCP like. (856 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | EPHA4 | EPH receptor A4. (949 aa) |
| | PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (313 aa) |
| | TXN | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] (105 aa) |
| | EDF1 | Endothelial differentiation related factor 1. (148 aa) |
| | F6SJC9_HORSE | Ig-like domain-containing protein. (324 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (860 aa) |
| | BAG2 | BCL2 associated athanogene 2. (211 aa) |
| | PEX14 | Peroxisomal biogenesis factor 14. (374 aa) |
| | SRC | Tyrosine-protein kinase. (551 aa) |
| | MSX2 | Msh homeobox 2. (260 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | NSD1 | Nuclear receptor binding SET domain protein 1. (2431 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | CRMP1 | Collapsin response mediator protein 1. (686 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1209 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1412 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (932 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2528 aa) |
| | TRIM28 | Tripartite motif containing 28. (821 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) |
| | GATA1 | GATA binding protein 1. (486 aa) |
| | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (248 aa) |
| | CLN5 | Uncharacterized protein. (352 aa) |
| | MAPRE1 | Microtubule associated protein RP/EB family member 1. (285 aa) |
| | TMC8 | Transmembrane channel-like protein. (716 aa) |
| | EP300 | E1A binding protein p300. (2430 aa) |
| | GMNN | Geminin DNA replication inhibitor. (211 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (739 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (217 aa) |
| | FAM192A | Family with sequence similarity 192 member A. (254 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1244 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (249 aa) |
| | MED25 | Mediator complex subunit 25. (746 aa) |
| | CSF3 | Colony stimulating factor 3. (204 aa) |
| | SYMPK | Symplekin. (1270 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (215 aa) |
| | ANKRD33 | Ankyrin repeat domain 33. (274 aa) |
| | TXNDC2 | Thioredoxin domain containing 2. (467 aa) |
| | RFNG | Beta-1,3-N-acetylglucosaminyltransferase. (328 aa) |
| | BTAF1 | B-TFIID TATA-box binding protein associated factor 1. (1849 aa) |
| | CLIC2 | Chloride intracellular channel 2. (247 aa) |
| | WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (549 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2570 aa) |
| | ZFP90 | ZFP90 zinc finger protein. (633 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | TTBK1 | Tau tubulin kinase 1. (1409 aa) |
| | TTC36 | Tetratricopeptide repeat domain 36. (188 aa) |
| | PHLDA2 | Pleckstrin homology like domain family A member 2. (157 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (164 aa) |
| | TRIM21 | Tripartite motif containing 21. (469 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (233 aa) |
| | LDOC1 | LDOC1 regulator of NFKB signaling. (146 aa) |
| | F7A4E6_HORSE | DUF4939 domain-containing protein. (215 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (597 aa) |
| | HAND1 | Heart and neural crest derivatives expressed 1. (218 aa) |
| | RNF220 | Ring finger protein 220. (566 aa) |
| | F6SXR8_HORSE | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (836 aa) |
| | XIRP1 | Uncharacterized protein. (1119 aa) |
| | LOC100058990 | Uncharacterized protein. (464 aa) |
| | LOC100050599 | Uncharacterized protein. (281 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | GREM2 | Gremlin. (168 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (301 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (353 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa) |
| | GTF2F1 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (557 aa) |
| | PABPN1L | Poly(A) binding protein nuclear 1 like, cytoplasmic. (271 aa) |
| | NMD3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (511 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | NES | Nestin; Belongs to the intermediate filament family. (1795 aa) |
| | PARK7 | Parkinsonism associated deglycase. (268 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (334 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (604 aa) |
| | BLK | Tyrosine-protein kinase. (500 aa) |
| | S100A10 | S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (309 aa) |
| | EFHB | EF-hand domain family member B. (850 aa) |
| | ACD | ACD shelterin complex subunit and telomerase recruitment factor. (455 aa) |
| | DDRGK1 | DDRGK domain containing 1. (315 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (244 aa) |
| | AKTIP | AKT interacting protein. (293 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | MSX1 | Msh homeobox 1. (303 aa) |
| | ZNF618 | Zinc finger protein 618. (1005 aa) |
| | SPON1 | Spondin 1. (807 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (700 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa) |
| | BMP2 | Bone morphogenetic protein 2. (397 aa) |
| | PAX6 | Paired box 6. (436 aa) |
| | MMP1 | Interstitial collagenase. (520 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | APP | Amyloid beta precursor protein. (811 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1117 aa) |
| | PLAUR | Plasminogen activator, urokinase receptor. (334 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | TFAP4 | Transcription factor AP-4. (338 aa) |
| | RACK1 | WD_REPEATS_REGION domain-containing protein. (317 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2428 aa) |
| | CTBP2 | C-terminal binding protein 2. (980 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (754 aa) |
| | LOC100056283 | Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa) |
| | GZMA | Granzyme A; Belongs to the peptidase S1 family. (321 aa) |
| | TEX14 | Testis expressed 14, intercellular bridge forming factor. (1533 aa) |
| | CAMK1 | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (412 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | ZNF593 | Zinc finger protein 593. (134 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (340 aa) |
| | TTBK2 | Tau tubulin kinase 2. (1244 aa) |
| | MEPCE | Methylphosphate capping enzyme. (687 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (200 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | ADD2 | Adducin 2. (724 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1274 aa) |
| | GTF2B | Transcription initiation factor IIB-like protein. (316 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (361 aa) |
| | MYOCD | Myocardin. (987 aa) |
| | CDON | Cell adhesion associated, oncogene regulated. (1283 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | PBXIP1 | PBX homeobox interacting protein 1. (766 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | USP33 | Ubiquitinyl hydrolase 1. (1062 aa) |
| | NIBAN2 | Niban apoptosis regulator 2. (848 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (793 aa) |
| | LRPAP1 | LDL receptor related protein associated protein 1. (608 aa) |
| | GATA3 | GATA binding protein 3. (445 aa) |
| | DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1804 aa) |
| | STK3 | Serine/threonine kinase 3. (574 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (669 aa) |
| | LOC102149514 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (421 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1098 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | CCPG1 | Cell cycle progression 1. (834 aa) |
| | STING1 | Transmembrane protein 173. (405 aa) |
| | LARP6 | La ribonucleoprotein domain family member 6. (492 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (347 aa) |
| | IRF4 | Interferon regulatory factor 4. (606 aa) |
| | LIF | LIF interleukin 6 family cytokine. (203 aa) |
| | HABP4 | Hyaluronan binding protein 4. (421 aa) |
| | MRLN | Uncharacterized protein. (46 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa) |
| | LOC111774145 | Ubiquitin associated and SH3 domain containing B. (634 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (794 aa) |
| | HJURP | Holliday junction recognition protein. (730 aa) |
| | LHX2 | LIM homeobox 2. (406 aa) |
| | NPHP3 | Nephrocystin 3. (1505 aa) |
| | PLXND1 | Plexin D1. (2046 aa) |
| | SORL1 | Sortilin related receptor 1. (2255 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (769 aa) |
| | SIRT2 | Sirtuin 2. (462 aa) |
| | CBLB | Cbl proto-oncogene B. (1189 aa) |
| | UBASH3B | Uncharacterized protein. (649 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | STK4 | Serine/threonine kinase 4. (493 aa) |
| | NEK2 | NIMA related kinase 2. (422 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1447 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | SPPL3 | Signal peptide peptidase like 3. (434 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | SPAG8 | Sperm associated antigen 8. (426 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (569 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (970 aa) |
| | EPHB6 | EPH receptor B6. (1011 aa) |
| | IDE | Insulin degrading enzyme. (1212 aa) |
| | DAB2 | DAB adaptor protein 2. (765 aa) |
| | STYX | Serine/threonine/tyrosine interacting protein. (223 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (832 aa) |
| | GNL3L | G protein nucleolar 3 like. (582 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (986 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (717 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (299 aa) |
| | CCPG1-2 | Uncharacterized protein. (851 aa) |
| | KRIT1 | KRIT1 ankyrin repeat containing. (727 aa) |
| | MDFI | MyoD family inhibitor. (536 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (494 aa) |
| | PTPRF | Protein tyrosine phosphatase receptor type F. (1923 aa) |
| | DHRS7B | Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (399 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (413 aa) |
| | ZBTB7C | Zinc finger and BTB domain containing 7C. (664 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1332 aa) |
| | MARK3 | Non-specific serine/threonine protein kinase. (753 aa) |
| | RB1 | RB transcriptional corepressor 1. (965 aa) |
| | HMGA2 | Uncharacterized protein. (156 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | ANKRD33B | ANK_REP_REGION domain-containing protein. (922 aa) |
| | RIPOR3 | RIPOR family member 3. (951 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | DTNBP1 | Dystrobrevin binding protein 1. (403 aa) |
| | RIPOR2 | RHO family interacting cell polarization regulator 2. (1224 aa) |
| | LOC100630879 | Uncharacterized protein. (823 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4267 aa) |
| | DISC1 | DISC1 scaffold protein. (890 aa) |
| | ENSECAP00000044250 | Peptidase S1 domain-containing protein. (156 aa) |
| | LRP1 | LDL receptor related protein 1. (4567 aa) |
| | DZIP1 | DAZ interacting zinc finger protein 1. (1005 aa) |
| | LOC111767410 | Cell cycle progression protein 1-like. (834 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1722 aa) |
| | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (543 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | ARHGEF7 | Rho guanine nucleotide exchange factor 7. (893 aa) |
| | SRI | Sorcin. (216 aa) |
| | FMR1 | Fragile X mental retardation 1. (632 aa) |
| | ARHGAP28 | Rho GTPase activating protein 28. (728 aa) |
| | ZNF462 | Zinc finger protein 462. (2564 aa) |
| | KDM1A | Lysine demethylase 1A. (1007 aa) |
| | SKI | Ski oncogene; May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling (By similarity); Belongs to the SKI family. (763 aa) |
| | WAPL | WAPL cohesin release factor. (1202 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (325 aa) |
| | SMIM6 | Small integral membrane protein 6. (60 aa) |
| | PLCL1 | Phosphoinositide phospholipase C. (1096 aa) |
| | CBLC | ANK_REP_REGION domain-containing protein. (912 aa) |
| | ZC4H2 | Zinc finger C4H2-type containing. (272 aa) |
| | AMFR | Autocrine motility factor receptor. (760 aa) |
| | LRRC6 | Leucine rich repeat containing 6. (782 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (477 aa) |
| | GEMIN2 | Gem nuclear organelle associated protein 2. (346 aa) |
| | HIP1R | Huntingtin interacting protein 1 related. (1203 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa) |
| | ZNF304 | Zinc finger protein 304. (660 aa) |
