STRINGSTRING
ANKRD11 ANKRD11 BRAF BRAF TGFB3 TGFB3 CSRNP1 CSRNP1 HOXB3 HOXB3 CHD7 CHD7 CRISPLD1 CRISPLD1 SRF SRF ALDH1A3 ALDH1A3 EP300 EP300 TGFB1 TGFB1 RAF1 RAF1 PAX9 PAX9 ENSECAP00000050004 ENSECAP00000050004 MAPK1 MAPK1 STRA6 STRA6 PDGFRA PDGFRA MKKS MKKS RAB3GAP1 RAB3GAP1 ENSECAP00000039203 ENSECAP00000039203 LEF1 LEF1 EDNRA EDNRA SGPL1 SGPL1 SCHIP1 SCHIP1 ZIC3 ZIC3 MAPK3 MAPK3 PLEKHA1 PLEKHA1 ALDH1A2 ALDH1A2 RARG RARG NIPBL NIPBL DLX5 DLX5 MSX1 MSX1 ZFAND5 ZFAND5 TIPARP TIPARP PTPN11 PTPN11 CRISPLD2 CRISPLD2 BBS4 BBS4 RRAS RRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANKRD11Ankyrin repeat domain 11. (2658 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (793 aa)
TGFB3Transforming growth factor beta 3. (490 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (608 aa)
HOXB3Homeobox B3. (421 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
SRFSerum response factor. (512 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
EP300E1A binding protein p300. (2430 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PAX9Paired box 9. (386 aa)
ENSECAP00000050004Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (323 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (594 aa)
STRA6Stimulated by retinoic acid 6. (711 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
ENSECAP00000039203Uncharacterized protein. (223 aa)
LEF1Lymphoid enhancer binding factor 1. (413 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (610 aa)
SCHIP1SCHIP-1 domain-containing protein. (500 aa)
ZIC3Zic family member 3. (535 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
PLEKHA1Pleckstrin homology domain containing A1. (438 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
RARGRetinoic acid receptor gamma. (541 aa)
NIPBLNipped-B protein. (2805 aa)
DLX5Distal-less homeobox 5. (289 aa)
MSX1Msh homeobox 1. (303 aa)
ZFAND5Zinc finger AN1-type containing 5. (216 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (680 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (606 aa)
CRISPLD2Cysteine rich secretory protein LCCL domain containing 2. (570 aa)
BBS4Bardet-Biedl syndrome 4. (531 aa)
RRASRAS related. (220 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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