(30 nodes) Positive regulation of wound healing network (Equus caballus)

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Predicted Interactions

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Your Input:
	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (402 aa)
	SERPINF2	Serpin family F member 2; Belongs to the serpin family. (491 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (605 aa)
	DMTN	Dematin actin binding protein. (405 aa)
	XBP1	BZIP domain-containing protein. (378 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2573 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (808 aa)
	INSL3	IlGF domain-containing protein. (133 aa)
	KANK1	KN motif and ankyrin repeat domains 1. (1433 aa)
	ENPP4	Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa)
	SMOC2	SPARC related modular calcium binding 2. (646 aa)
	RREB1	Ras responsive element binding protein 1. (1773 aa)
	ANO6	Anoctamin. (996 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
	HBEGF	Heparin binding EGF like growth factor. (390 aa)
	CCN4	Cellular communication network factor 4. (368 aa)
	HPSE	Heparanase. (544 aa)
	APOH	Apolipoprotein H. (345 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	FERMT2	Fermitin family member 2. (707 aa)
	ARFGEF1	ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
	ANXA1	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
	F12	Coagulation factor XII. (615 aa)
	THBS1	Thrombospondin 1. (1170 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	F2R	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
	ADRA2A	Adrenoceptor alpha 2A. (465 aa)
	FERMT1	Fermitin family member 1. (677 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	F2	ENSECAP00000013992	ENSECAP00000009701	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.439
ANXA1	THBS1	ENSECAP00000013992	ENSECAP00000007423	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	Thrombospondin 1.	0.404
APOH	F12	ENSECAP00000019727	ENSECAP00000008812	Apolipoprotein H.	Coagulation factor XII.	0.467
APOH	F2	ENSECAP00000019727	ENSECAP00000009701	Apolipoprotein H.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.897
APOH	SERPINF2	ENSECAP00000019727	ENSECAP00000052579	Apolipoprotein H.	Serpin family F member 2; Belongs to the serpin family.	0.652
CLDN1	CLDN3	ENSECAP00000018497	ENSECAP00000025565	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.768
CLDN1	CLDN4	ENSECAP00000018497	ENSECAP00000004574	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.767
CLDN3	CLDN1	ENSECAP00000025565	ENSECAP00000018497	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.768
CLDN3	CLDN4	ENSECAP00000025565	ENSECAP00000004574	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.663
CLDN4	CLDN1	ENSECAP00000004574	ENSECAP00000018497	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.767
CLDN4	CLDN3	ENSECAP00000004574	ENSECAP00000025565	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.663
F12	APOH	ENSECAP00000008812	ENSECAP00000019727	Coagulation factor XII.	Apolipoprotein H.	0.467
F12	F2	ENSECAP00000008812	ENSECAP00000009701	Coagulation factor XII.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.572
F12	SERPINF2	ENSECAP00000008812	ENSECAP00000052579	Coagulation factor XII.	Serpin family F member 2; Belongs to the serpin family.	0.574
F2	ANXA1	ENSECAP00000009701	ENSECAP00000013992	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	0.439
F2	APOH	ENSECAP00000009701	ENSECAP00000019727	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Apolipoprotein H.	0.897
F2	F12	ENSECAP00000009701	ENSECAP00000008812	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor XII.	0.572
F2	F2R	ENSECAP00000009701	ENSECAP00000002827	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	0.997
F2	SERPINF2	ENSECAP00000009701	ENSECAP00000052579	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family F member 2; Belongs to the serpin family.	0.884
F2R	F2	ENSECAP00000002827	ENSECAP00000009701	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.997