(34 nodes) Positive regulation of neural precursor cell proliferation network (Equus caballus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LHX1	LIM homeobox 1. (405 aa)
	SOX10	SRY-box transcription factor 10. (546 aa)
	ZNF335	Zinc finger protein 335. (1334 aa)
	PAX6	Paired box 6. (436 aa)
	GPR37L1	G protein-coupled receptor 37 like 1. (482 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (385 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	LHX5	LIM homeobox 5. (402 aa)
	ELL3	Elongation factor for RNA polymerase II 3. (395 aa)
	CIP2A	Cell proliferation regulating inhibitor of protein phosphatase 2A. (908 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	GLI1	GLI family zinc finger 1. (1106 aa)
	OTP	Orthopedia homeobox. (325 aa)
	CTNNB1	Beta catenin 1. (781 aa)
	CDON	Cell adhesion associated, oncogene regulated. (1283 aa)
	DCT	Dopachrome tautomerase. (548 aa)
	FOXG1	Forkhead box G1. (531 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (844 aa)
	KDM1A	Lysine demethylase 1A. (1007 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (808 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (325 aa)
	GLI3	GLI family zinc finger 3. (1581 aa)
	DISP3	Dispatched RND transporter family member 3. (1393 aa)
	DISC1	DISC1 scaffold protein. (890 aa)
	LRP2	LDL receptor related protein 2. (4673 aa)
	TOX	Thymocyte selection associated high mobility group box. (526 aa)
	DMRTA2	DMRT like family A2. (536 aa)
	ZNF423	Zinc finger protein 423. (1352 aa)
	LHX2	LIM homeobox 2. (406 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
	ADGRG1	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (691 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	FGF2	ENSECAP00000045751	ENSECAP00000012430	Achaete-scute family bHLH transcription factor 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.434
ASCL1	FOXG1	ENSECAP00000045751	ENSECAP00000052733	Achaete-scute family bHLH transcription factor 1.	Forkhead box G1.	0.571
ASCL1	LHX1	ENSECAP00000045751	ENSECAP00000001559	Achaete-scute family bHLH transcription factor 1.	LIM homeobox 1.	0.522
ASCL1	LHX2	ENSECAP00000045751	ENSECAP00000028749	Achaete-scute family bHLH transcription factor 1.	LIM homeobox 2.	0.629
ASCL1	LHX5	ENSECAP00000045751	ENSECAP00000014611	Achaete-scute family bHLH transcription factor 1.	LIM homeobox 5.	0.446
ASCL1	PAX6	ENSECAP00000045751	ENSECAP00000018871	Achaete-scute family bHLH transcription factor 1.	Paired box 6.	0.736
ASCL1	SOX10	ENSECAP00000045751	ENSECAP00000021648	Achaete-scute family bHLH transcription factor 1.	SRY-box transcription factor 10.	0.734
CDON	CTNNB1	ENSECAP00000022788	ENSECAP00000005466	Cell adhesion associated, oncogene regulated.	Beta catenin 1.	0.414
CDON	GLI1	ENSECAP00000022788	ENSECAP00000009189	Cell adhesion associated, oncogene regulated.	GLI family zinc finger 1.	0.566
CDON	GLI3	ENSECAP00000022788	ENSECAP00000045184	Cell adhesion associated, oncogene regulated.	GLI family zinc finger 3.	0.686
CDON	LRP2	ENSECAP00000022788	ENSECAP00000040585	Cell adhesion associated, oncogene regulated.	LDL receptor related protein 2.	0.914
CDON	SMO	ENSECAP00000022788	ENSECAP00000028203	Cell adhesion associated, oncogene regulated.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.852
CTNNB1	CDON	ENSECAP00000005466	ENSECAP00000022788	Beta catenin 1.	Cell adhesion associated, oncogene regulated.	0.414
CTNNB1	DLL4	ENSECAP00000005466	ENSECAP00000011160	Beta catenin 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.445
CTNNB1	FGF2	ENSECAP00000005466	ENSECAP00000012430	Beta catenin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.534
CTNNB1	FOXG1	ENSECAP00000005466	ENSECAP00000052733	Beta catenin 1.	Forkhead box G1.	0.484
CTNNB1	FZD3	ENSECAP00000005466	ENSECAP00000015953	Beta catenin 1.	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.647
CTNNB1	GLI1	ENSECAP00000005466	ENSECAP00000009189	Beta catenin 1.	GLI family zinc finger 1.	0.599
CTNNB1	GLI3	ENSECAP00000005466	ENSECAP00000045184	Beta catenin 1.	GLI family zinc finger 3.	0.424
CTNNB1	HIF1A	ENSECAP00000005466	ENSECAP00000048740	Beta catenin 1.	Hypoxia inducible factor 1 subunit alpha.	0.874