STRINGSTRING
RNASE10 RNASE10 F6TZF9_HORSE F6TZF9_HORSE ZP1 ZP1 IQCF5 IQCF5 F6SBT5_HORSE F6SBT5_HORSE CCDC87 CCDC87 AGO2 AGO2 DHX37 DHX37 F6V4F0_HORSE F6V4F0_HORSE IQCF1 IQCF1 ZP3 ZP3 OIT3 OIT3 CFAP69 CFAP69 ZP4 ZP4 C1QBP C1QBP MSX2 MSX2 ACVR1B ACVR1B CPT1B CPT1B TACR3 TACR3 VIP VIP NR5A1 NR5A1 INHBB INHBB STRA8 STRA8 PRDM14 PRDM14 PLA2G10 PLA2G10 MEIOC MEIOC TACR1 TACR1 OVOL1 OVOL1 HYAL3 HYAL3 CIB1 CIB1 FBXO42 FBXO42 FGF9 FGF9 UNC5C UNC5C MSX1 MSX1 LHFPL2 LHFPL2 SOX9 SOX9 INHBA INHBA GLRA1 GLRA1 CACNA1H CACNA1H FAM170B FAM170B NPM2 NPM2 PIWIL2 PIWIL2 PDE3A PDE3A APELA APELA LOC111770992 LOC111770992 CDC25A CDC25A ANKRD31 ANKRD31 SIRT2 SIRT2 BNC1 BNC1 PRSS37 PRSS37 CITED2 CITED2 NR5A2 NR5A2 CCR6 CCR6 ENSECAP00000037769 ENSECAP00000037769 CDC25B CDC25B MAPK15 MAPK15 ENSECAP00000042077 ENSECAP00000042077 ZFPM2 ZFPM2 BHMG1 BHMG1 TACR2 TACR2 AURKA AURKA LFNG LFNG SMURF2 SMURF2 CDC25C CDC25C ZNF112 ZNF112 SYDE1 SYDE1 ENSECAP00000052123 ENSECAP00000052123 PRDM7 PRDM7 RAD51AP1 RAD51AP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNASE10Inactive ribonuclease-like protein 10; Secreted proximal epididymal protein required for post- testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity). (213 aa)
F6TZF9_HORSEMOEP19 domain-containing protein. (181 aa)
ZP1Zona pellucida glycoprotein 1. (619 aa)
IQCF5IQ motif containing F5. (152 aa)
F6SBT5_HORSEUncharacterized protein. (143 aa)
CCDC87Coiled-coil domain containing 87. (1021 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa)
DHX37DEAH-box helicase 37. (1149 aa)
F6V4F0_HORSEDEFSN domain-containing protein. (64 aa)
IQCF1IQ motif containing F1. (207 aa)
ZP3ZP domain-containing protein. (426 aa)
OIT3Oncoprotein induced transcript 3. (546 aa)
CFAP69Cilia and flagella associated protein 69. (940 aa)
ZP4Zona pellucida glycoprotein 4. (476 aa)
C1QBPComplement C1q binding protein. (279 aa)
MSX2Msh homeobox 2. (260 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
CPT1BSynaptonemal complex central element protein 3. (88 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (438 aa)
VIPVasoactive intestinal peptide. (171 aa)
NR5A1Steroidogenic factor 1; Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phospholipi [...] (557 aa)
INHBBInhibin subunit beta B. (928 aa)
STRA8Stimulated by retinoic acid 8. (374 aa)
PRDM14PR/SET domain 14. (598 aa)
PLA2G10Phospholipase A(2). (160 aa)
MEIOCMeiosis specific with coiled-coil domain. (1036 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
HYAL3Hyaluronidase. (415 aa)
CIB1Calcium and integrin binding 1. (191 aa)
FBXO42F-box protein 42. (747 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
MSX1Msh homeobox 1. (303 aa)
LHFPL2LHFPL tetraspan subfamily member 2. (226 aa)
SOX9SRY-box 9. (509 aa)
INHBAInhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (426 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2359 aa)
FAM170BFamily with sequence similarity 170 member B. (372 aa)
NPM2Nucleophosmin/nucleoplasmin 2. (217 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (969 aa)
PDE3APhosphodiesterase. (1144 aa)
APELAUncharacterized protein. (53 aa)
LOC111770992MOEP19 domain-containing protein. (151 aa)
CDC25ACell division cycle 25A. (524 aa)
ANKRD31Ankyrin repeat domain 31. (1955 aa)
SIRT2Sirtuin 2. (462 aa)
BNC1Basonuclin 1. (1192 aa)
PRSS37Serine protease 37. (251 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (294 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (586 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (374 aa)
ENSECAP00000037769MOEP19 domain-containing protein. (337 aa)
CDC25BCell division cycle 25B. (716 aa)
MAPK15Mitogen-activated protein kinase. (630 aa)
ENSECAP00000042077Uncharacterized protein. (148 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1150 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (691 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (392 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (423 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (543 aa)
SMURF2E3 ubiquitin-protein ligase. (753 aa)
CDC25CCell division cycle 25C. (510 aa)
ZNF112Zinc finger protein 112. (913 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (807 aa)
ENSECAP00000052123MOEP19 domain-containing protein. (410 aa)
PRDM7Uncharacterized protein. (887 aa)
RAD51AP1RAD51 associated protein 1. (335 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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