(37 nodes) Regulation of synaptic vesicle exocytosis network (Equus caballus)

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second shell of interactors

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Predicted Interactions

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Your Input:
	SYP	Synaptophysin. (313 aa)
	VPS18	VPS18 core subunit of CORVET and HOPS complexes. (976 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (843 aa)
	CACNB2	Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
	FBXL20	F-box and leucine rich repeat protein 20. (438 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	CACNB4	Calcium voltage-gated channel auxiliary subunit beta 4. (519 aa)
	NLGN1	Neuroligin 1. (823 aa)
	GIPC1	GIPC PDZ domain containing family member 1. (332 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	GIPC3	GIPC PDZ domain containing family member 3. (312 aa)
	DTNBP1	Dystrobrevin binding protein 1. (403 aa)
	RAB5A	RAB5A, member RAS oncogene family. (215 aa)
	CHRM2	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (496 aa)
	STXBP5L	Syntaxin binding protein 5 like. (1234 aa)
	STXBP5	Syntaxin binding protein 5. (1162 aa)
	PFN2	Profilin; Belongs to the profilin family. (188 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (793 aa)
	SNTN	Synaptoporin. (416 aa)
	SLC4A8	Anion exchange protein. (1106 aa)
	DGKI	Diacylglycerol kinase. (1078 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa)
	CHRNA5	Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
	DVL1	Dishevelled segment polarity protein 1. (700 aa)
	SNAPIN	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
	ADRA2A	Adrenoceptor alpha 2A. (465 aa)
	RAP1B	Ras-related protein Rap-1b-like protein. (184 aa)
	LOC100049912	Uncharacterized protein. (184 aa)
	PREPL	Prolyl endopeptidase like. (727 aa)
	GIT1	GIT ArfGAP 1. (770 aa)
	GIPC2	GIPC PDZ domain containing family member 2. (314 aa)
	LRRK2	Leucine rich repeat kinase 2. (2528 aa)
	SYT2	Synaptotagmin 2. (419 aa)
	BACE1	Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
	SYT1	Synaptotagmin 1. (422 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADRA2A	ENSECAP00000022626	ENSECAP00000002636	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adrenoceptor alpha 2A.	0.586
ADCY1	PRKCB	ENSECAP00000022626	ENSECAP00000042034	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.716
ADRA2A	ADCY1	ENSECAP00000002636	ENSECAP00000022626	Adrenoceptor alpha 2A.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.586
ADRA2A	RAP1B	ENSECAP00000002636	ENSECAP00000003835	Adrenoceptor alpha 2A.	Ras-related protein Rap-1b-like protein.	0.407
APBA1	SYT1	ENSECAP00000053895	ENSECAP00000010875	Amyloid beta precursor protein binding family A member 1.	Synaptotagmin 1.	0.404
APBA1	SYT2	ENSECAP00000053895	ENSECAP00000008886	Amyloid beta precursor protein binding family A member 1.	Synaptotagmin 2.	0.404
BACE1	GSK3B	ENSECAP00000010514	ENSECAP00000022500	Beta-secretase 1; Belongs to the peptidase A1 family.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.497
BACE1	SYP	ENSECAP00000010514	ENSECAP00000012847	Beta-secretase 1; Belongs to the peptidase A1 family.	Synaptophysin.	0.837
BRAF	GSK3B	ENSECAP00000029059	ENSECAP00000022500	B-Raf proto-oncogene, serine/threonine kinase.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.912
BRAF	LOC100049912	ENSECAP00000029059	ENSECAP00000004325	B-Raf proto-oncogene, serine/threonine kinase.	Uncharacterized protein.	0.965
BRAF	PRKCB	ENSECAP00000029059	ENSECAP00000042034	B-Raf proto-oncogene, serine/threonine kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.915
BRAF	RAP1A	ENSECAP00000029059	ENSECAP00000014122	B-Raf proto-oncogene, serine/threonine kinase.	RAP1A, member of RAS oncogene family.	0.668
BRAF	RAP1B	ENSECAP00000029059	ENSECAP00000003835	B-Raf proto-oncogene, serine/threonine kinase.	Ras-related protein Rap-1b-like protein.	0.978
CACNB2	CACNB4	ENSECAP00000052408	ENSECAP00000049956	Calcium voltage-gated channel auxiliary subunit beta 2.	Calcium voltage-gated channel auxiliary subunit beta 4.	0.756
CACNB4	CACNB2	ENSECAP00000049956	ENSECAP00000052408	Calcium voltage-gated channel auxiliary subunit beta 4.	Calcium voltage-gated channel auxiliary subunit beta 2.	0.756
CHRM2	CHRNA5	ENSECAP00000038522	ENSECAP00000018914	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Cholinergic receptor nicotinic alpha 5 subunit.	0.559
CHRNA5	CHRM2	ENSECAP00000018914	ENSECAP00000038522	Cholinergic receptor nicotinic alpha 5 subunit.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.559
DTNBP1	SNAPIN	ENSECAP00000040643	ENSECAP00000017898	Dystrobrevin binding protein 1.	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]	0.987
DVL1	GSK3B	ENSECAP00000018472	ENSECAP00000022500	Dishevelled segment polarity protein 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.964
DVL1	LRRK2	ENSECAP00000018472	ENSECAP00000008861	Dishevelled segment polarity protein 1.	Leucine rich repeat kinase 2.	0.468