| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NSMCE1 | NSMCE2 | ENSECAP00000025511 | ENSECAP00000023088 | NSE1 homolog, SMC5-SMC6 complex component. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.998 |
| NSMCE1 | NSMCE4A | ENSECAP00000025511 | ENSECAP00000014399 | NSE1 homolog, SMC5-SMC6 complex component. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.999 |
| NSMCE1 | SMC5 | ENSECAP00000025511 | ENSECAP00000032811 | NSE1 homolog, SMC5-SMC6 complex component. | Structural maintenance of chromosomes 5. | 0.998 |
| NSMCE1 | SMC6 | ENSECAP00000025511 | ENSECAP00000019939 | NSE1 homolog, SMC5-SMC6 complex component. | Structural maintenance of chromosomes 6. | 0.998 |
| NSMCE2 | NSMCE1 | ENSECAP00000023088 | ENSECAP00000025511 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | NSE1 homolog, SMC5-SMC6 complex component. | 0.998 |
| NSMCE2 | NSMCE4A | ENSECAP00000023088 | ENSECAP00000014399 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.996 |
| NSMCE2 | RAD52 | ENSECAP00000023088 | ENSECAP00000016377 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | RAD52 homolog, DNA repair protein. | 0.413 |
| NSMCE2 | SMC5 | ENSECAP00000023088 | ENSECAP00000032811 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | Structural maintenance of chromosomes 5. | 0.998 |
| NSMCE2 | SMC6 | ENSECAP00000023088 | ENSECAP00000019939 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | Structural maintenance of chromosomes 6. | 0.996 |
| NSMCE4A | NSMCE1 | ENSECAP00000014399 | ENSECAP00000025511 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | NSE1 homolog, SMC5-SMC6 complex component. | 0.999 |
| NSMCE4A | NSMCE2 | ENSECAP00000014399 | ENSECAP00000023088 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.996 |
| NSMCE4A | SMC5 | ENSECAP00000014399 | ENSECAP00000032811 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Structural maintenance of chromosomes 5. | 0.998 |
| NSMCE4A | SMC6 | ENSECAP00000014399 | ENSECAP00000019939 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | Structural maintenance of chromosomes 6. | 0.999 |
| RAD52 | NSMCE2 | ENSECAP00000016377 | ENSECAP00000023088 | RAD52 homolog, DNA repair protein. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.413 |
| RAD52 | SMC5 | ENSECAP00000016377 | ENSECAP00000032811 | RAD52 homolog, DNA repair protein. | Structural maintenance of chromosomes 5. | 0.645 |
| RAD52 | SMC6 | ENSECAP00000016377 | ENSECAP00000019939 | RAD52 homolog, DNA repair protein. | Structural maintenance of chromosomes 6. | 0.673 |
| SMC5 | NSMCE1 | ENSECAP00000032811 | ENSECAP00000025511 | Structural maintenance of chromosomes 5. | NSE1 homolog, SMC5-SMC6 complex component. | 0.998 |
| SMC5 | NSMCE2 | ENSECAP00000032811 | ENSECAP00000023088 | Structural maintenance of chromosomes 5. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.998 |
| SMC5 | NSMCE4A | ENSECAP00000032811 | ENSECAP00000014399 | Structural maintenance of chromosomes 5. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.998 |
| SMC5 | RAD52 | ENSECAP00000032811 | ENSECAP00000016377 | Structural maintenance of chromosomes 5. | RAD52 homolog, DNA repair protein. | 0.645 |