(24 nodes) SEA domain network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TMPRSS11B	Transmembrane protease serine; Belongs to the peptidase S1 family. (417 aa)
	ST14	Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
	TMPRSS11A	Transmembrane protease serine; Belongs to the peptidase S1 family. (417 aa)
	TMPRSS11D	Transmembrane protease serine; Belongs to the peptidase S1 family. (418 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
	TMPRSS6	Transmembrane serine protease 6; Belongs to the peptidase S1 family. (808 aa)
	AGRN	Agrin. (2071 aa)
	F7C2N1_HORSE	Transmembrane protease serine; Belongs to the peptidase S1 family. (433 aa)
	ADGRF1	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (956 aa)
	TMPRSS9	Transmembrane serine protease 9; Belongs to the peptidase S1 family. (1181 aa)
	IMPG1	Interphotoreceptor matrix proteoglycan 1. (757 aa)
	TMPRSS11E	Transmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)
	LOC100067439	Transmembrane protease serine; Belongs to the peptidase S1 family. (428 aa)
	ENSECAP00000035654	SEA domain-containing protein. (339 aa)
	MUC13	Uncharacterized protein. (466 aa)
	HSPG2	Heparan sulfate proteoglycan 2. (4395 aa)
	MUC16	SEA domain-containing protein. (1933 aa)
	LOC100067368	Transmembrane protease serine; Belongs to the peptidase S1 family. (418 aa)
	UMODL1	Uromodulin like 1. (1358 aa)
	IMPG2	Interphotoreceptor matrix proteoglycan 2. (1305 aa)
	TMPRSS15	Transmembrane serine protease 15; Belongs to the peptidase S1 family. (1019 aa)
	TMPRSS7	Transmembrane serine protease 7. (829 aa)
	TMPRSS11F	Transmembrane serine protease 11F; Belongs to the peptidase S1 family. (449 aa)
	MUC1	Mucin 1, cell surface associated. (714 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	HSPG2	ENSECAP00000035833	ENSECAP00000054621	Agrin.	Heparan sulfate proteoglycan 2.	0.511
AGRN	TMPRSS15	ENSECAP00000035833	ENSECAP00000004391	Agrin.	Transmembrane serine protease 15; Belongs to the peptidase S1 family.	0.907
ENSECAP00000035654	MUC1	ENSECAP00000035654	ENSECAP00000004898	SEA domain-containing protein.	Mucin 1, cell surface associated.	0.494
ENSECAP00000035654	MUC16	ENSECAP00000035654	ENSECAP00000050439	SEA domain-containing protein.	SEA domain-containing protein.	0.491
HSPG2	AGRN	ENSECAP00000054621	ENSECAP00000035833	Heparan sulfate proteoglycan 2.	Agrin.	0.511
MUC1	ENSECAP00000035654	ENSECAP00000004898	ENSECAP00000035654	Mucin 1, cell surface associated.	SEA domain-containing protein.	0.494
MUC1	MUC13	ENSECAP00000004898	ENSECAP00000004673	Mucin 1, cell surface associated.	Uncharacterized protein.	0.875
MUC1	MUC16	ENSECAP00000004898	ENSECAP00000050439	Mucin 1, cell surface associated.	SEA domain-containing protein.	0.494
MUC1	TMPRSS15	ENSECAP00000004898	ENSECAP00000004391	Mucin 1, cell surface associated.	Transmembrane serine protease 15; Belongs to the peptidase S1 family.	0.764
MUC13	MUC1	ENSECAP00000004673	ENSECAP00000004898	Uncharacterized protein.	Mucin 1, cell surface associated.	0.875
MUC13	TMPRSS15	ENSECAP00000004673	ENSECAP00000004391	Uncharacterized protein.	Transmembrane serine protease 15; Belongs to the peptidase S1 family.	0.602
MUC16	ENSECAP00000035654	ENSECAP00000050439	ENSECAP00000035654	SEA domain-containing protein.	SEA domain-containing protein.	0.491
MUC16	MUC1	ENSECAP00000050439	ENSECAP00000004898	SEA domain-containing protein.	Mucin 1, cell surface associated.	0.494
TMPRSS15	AGRN	ENSECAP00000004391	ENSECAP00000035833	Transmembrane serine protease 15; Belongs to the peptidase S1 family.	Agrin.	0.907
TMPRSS15	MUC1	ENSECAP00000004391	ENSECAP00000004898	Transmembrane serine protease 15; Belongs to the peptidase S1 family.	Mucin 1, cell surface associated.	0.764
TMPRSS15	MUC13	ENSECAP00000004391	ENSECAP00000004673	Transmembrane serine protease 15; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.602