(22 nodes) PWWP domain network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZMYND11	Uncharacterized protein. (616 aa)
	DNMT3A	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
	PWWP2B	PWWP domain containing 2B. (586 aa)
	BRD1	Bromodomain containing 1. (1220 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
	CCNJL	Cyclin J like; Belongs to the cyclin family. (909 aa)
	GLYR1	Glyoxylate reductase 1 homolog. (597 aa)
	NSD1	Nuclear receptor binding SET domain protein 1. (2431 aa)
	DNMT3B	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)
	PSIP1	PC4 and SFRS1 interacting protein 1. (530 aa)
	ZMYND8	Zinc finger MYND-type containing 8. (1232 aa)
	HDGFL3	HDGF like 3. (203 aa)
	BRPF1	Bromodomain and PHD finger containing 1. (1220 aa)
	ZCWPW1	Zinc finger CW-type and PWWP domain containing 1. (644 aa)
	NSD3	Nuclear receptor binding SET domain protein 3. (1438 aa)
	MBD5	Methyl-CpG binding domain protein 5. (1732 aa)
	HDGFL1	PWWP domain-containing protein. (234 aa)
	ZCWPW2	Uncharacterized protein. (411 aa)
	ENSECAP00000031008	Uncharacterized protein. (566 aa)
	HDGFL2	HDGF like 2. (729 aa)
	NSD2	Nuclear receptor binding SET domain protein 2. (1412 aa)
	BRPF3	Bromodomain and PHD finger containing 3. (1207 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRD1	BRPF1	ENSECAP00000017970	ENSECAP00000018684	Bromodomain containing 1.	Bromodomain and PHD finger containing 1.	0.771
BRD1	BRPF3	ENSECAP00000017970	ENSECAP00000040125	Bromodomain containing 1.	Bromodomain and PHD finger containing 3.	0.886
BRD1	ZMYND11	ENSECAP00000017970	ENSECAP00000041632	Bromodomain containing 1.	Uncharacterized protein.	0.482
BRPF1	BRD1	ENSECAP00000018684	ENSECAP00000017970	Bromodomain and PHD finger containing 1.	Bromodomain containing 1.	0.771
BRPF1	BRPF3	ENSECAP00000018684	ENSECAP00000040125	Bromodomain and PHD finger containing 1.	Bromodomain and PHD finger containing 3.	0.809
BRPF1	GLYR1	ENSECAP00000018684	ENSECAP00000007463	Bromodomain and PHD finger containing 1.	Glyoxylate reductase 1 homolog.	0.460
BRPF1	ZMYND11	ENSECAP00000018684	ENSECAP00000041632	Bromodomain and PHD finger containing 1.	Uncharacterized protein.	0.623
BRPF3	BRD1	ENSECAP00000040125	ENSECAP00000017970	Bromodomain and PHD finger containing 3.	Bromodomain containing 1.	0.886
BRPF3	BRPF1	ENSECAP00000040125	ENSECAP00000018684	Bromodomain and PHD finger containing 3.	Bromodomain and PHD finger containing 1.	0.809
BRPF3	ZMYND11	ENSECAP00000040125	ENSECAP00000041632	Bromodomain and PHD finger containing 3.	Uncharacterized protein.	0.630
DNMT3A	DNMT3B	ENSECAP00000045160	ENSECAP00000010703	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.985
DNMT3B	DNMT3A	ENSECAP00000010703	ENSECAP00000045160	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.985
GLYR1	BRPF1	ENSECAP00000007463	ENSECAP00000018684	Glyoxylate reductase 1 homolog.	Bromodomain and PHD finger containing 1.	0.460
NSD2	ZCWPW2	ENSECAP00000039902	ENSECAP00000029968	Nuclear receptor binding SET domain protein 2.	Uncharacterized protein.	0.717
ZCWPW2	NSD2	ENSECAP00000029968	ENSECAP00000039902	Uncharacterized protein.	Nuclear receptor binding SET domain protein 2.	0.717
ZMYND11	BRD1	ENSECAP00000041632	ENSECAP00000017970	Uncharacterized protein.	Bromodomain containing 1.	0.482
ZMYND11	BRPF1	ENSECAP00000041632	ENSECAP00000018684	Uncharacterized protein.	Bromodomain and PHD finger containing 1.	0.623
ZMYND11	BRPF3	ENSECAP00000041632	ENSECAP00000040125	Uncharacterized protein.	Bromodomain and PHD finger containing 3.	0.630