(22 nodes) Interferon alpha/beta/delta network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100147174	Uncharacterized protein. (186 aa)
	LOC111767428	Interferon omega-1. (195 aa)
	LOC100053263	Uncharacterized protein. (195 aa)
	IFNE	Interferon epsilon. (171 aa)
	IFNB1	Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa)
	F7B4X7_HORSE	Uncharacterized protein. (113 aa)
	IFN-OMEGA2	Uncharacterized protein. (195 aa)
	LOC100053210	Uncharacterized protein. (184 aa)
	LOC100629859	Uncharacterized protein. (195 aa)
	IFND1	Uncharacterized protein. (167 aa)
	IFND2	Uncharacterized protein. (170 aa)
	IFNK	Interferon kappa. (208 aa)
	IFN-OMEGA1	Uncharacterized protein. (194 aa)
	IFN-ALPHA2	Interferon alpha-2; Produced by macrophages, IFN-alpha have antiviral activities. (184 aa)
	LOC100052971	Uncharacterized protein. (195 aa)
	LOC100053110	Interferon alpha-4; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (184 aa)
	IFNA1	Uncharacterized protein. (184 aa)
	LOC100053069	Interferon omega-2. (195 aa)
	LOC100629951	Interferon alpha-1; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (184 aa)
	LOC100629885	Uncharacterized protein. (167 aa)
	LOC100064612	Uncharacterized protein. (171 aa)
	LOC100052921	Uncharacterized protein. (184 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFNB1	IFNK	ENSECAP00000004620	ENSECAP00000019028	Interferon beta; Has antiviral, antibacterial and anticancer activities.	Interferon kappa.	0.494
IFNB1	LOC100147174	ENSECAP00000004620	ENSECAP00000050798	Interferon beta; Has antiviral, antibacterial and anticancer activities.	Uncharacterized protein.	0.900
IFNE	IFNK	ENSECAP00000002894	ENSECAP00000019028	Interferon epsilon.	Interferon kappa.	0.476
IFNK	IFNB1	ENSECAP00000019028	ENSECAP00000004620	Interferon kappa.	Interferon beta; Has antiviral, antibacterial and anticancer activities.	0.494
IFNK	IFNE	ENSECAP00000019028	ENSECAP00000002894	Interferon kappa.	Interferon epsilon.	0.476
IFNK	LOC100147174	ENSECAP00000019028	ENSECAP00000050798	Interferon kappa.	Uncharacterized protein.	0.482
LOC100147174	IFNB1	ENSECAP00000050798	ENSECAP00000004620	Uncharacterized protein.	Interferon beta; Has antiviral, antibacterial and anticancer activities.	0.900
LOC100147174	IFNK	ENSECAP00000050798	ENSECAP00000019028	Uncharacterized protein.	Interferon kappa.	0.482