STRINGSTRING
GRK3 GRK3 PRKX PRKX LATS1 LATS1 GRK1 GRK1 PRKCE PRKCE AKT2 AKT2 MAST2 MAST2 CDC42BPG CDC42BPG ROCK2 ROCK2 RPS6KA3 RPS6KA3 RPS6KB2 RPS6KB2 PRKCH PRKCH RPS6KB1 RPS6KB1 GRK7 GRK7 RPS6KA4 RPS6KA4 GRK4 GRK4 PRKCG PRKCG AKT3 AKT3 ROCK1 ROCK1 MAST1 MAST1 PRKCD PRKCD STK38L STK38L RPS6KA5 RPS6KA5 PRKG2 PRKG2 PKN2 PKN2 MAST3 MAST3 STK38 STK38 CDC42BPB CDC42BPB RPS6KA1 RPS6KA1 PKN1 PKN1 CIT CIT PRKCI PRKCI DMPK DMPK GRK5 GRK5 MASTL MASTL LATS2 LATS2 GRK2 GRK2 MAST4 MAST4 PRKACA PRKACA AKT1 AKT1 PRKCQ PRKCQ PRKCA PRKCA PRKCZ PRKCZ GRK6 GRK6 CDC42BPA CDC42BPA PRKACB PRKACB PRKG1 PRKG1 PRKCB PRKCB GRK3-2 GRK3-2 LOC100070683 LOC100070683 SGK1 SGK1 RPS6KA6 RPS6KA6 RPS6KA2 RPS6KA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRK3G protein-coupled receptor kinase 3. (1054 aa)
PRKXProtein kinase X-linked; Belongs to the protein kinase superfamily. (356 aa)
LATS1Large tumor suppressor kinase 1. (1128 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
AKT2Non-specific serine/threonine protein kinase. (528 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1806 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1549 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1468 aa)
RPS6KA3Ribosomal protein S6 kinase. (747 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
RPS6KA4Ribosomal protein S6 kinase. (771 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (577 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1571 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
RPS6KA5Ribosomal protein S6 kinase. (799 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PKN2Protein kinase N2. (983 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1329 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1728 aa)
RPS6KA1Ribosomal protein S6 kinase. (780 aa)
PKN1Protein kinase N1. (1098 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (655 aa)
DMPKDM1 protein kinase. (817 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (667 aa)
MASTLMicrotubule associated serine/threonine kinase like. (887 aa)
LATS2Non-specific serine/threonine protein kinase. (1088 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (704 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2642 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (359 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (811 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (609 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1810 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GRK3-2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (644 aa)
LOC100070683Non-specific serine/threonine protein kinase. (1178 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
RPS6KA6Ribosomal protein S6 kinase. (763 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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