(39 nodes) Laminin-type EGF domain network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LAMA3	Laminin subunit alpha 3. (3331 aa)
	LAMA1	Laminin subunit alpha 1. (3127 aa)
	MEGF6	Multiple EGF like domains 6. (1670 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3076 aa)
	TNN	Tenascin N. (1296 aa)
	NTNG1	Netrin G1. (581 aa)
	ATRN	Attractin. (1417 aa)
	HSPG2	Heparan sulfate proteoglycan 2. (4395 aa)
	TEK	TEK receptor tyrosine kinase. (1153 aa)
	CELSR2	Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2923 aa)
	NTN3	Netrin 3. (580 aa)
	NTN5	Netrin 5. (489 aa)
	LAMA4	Laminin subunit alpha 4. (1824 aa)
	MEGF8	Multiple EGF like domains 8. (2789 aa)
	SCARF1	Scavenger receptor class F member 1. (830 aa)
	CRELD2	Cysteine rich with EGF like domains 2. (356 aa)
	PEAR1	Platelet endothelial aggregation receptor 1. (1049 aa)
	LAMB2	Laminin subunit beta 2. (1801 aa)
	LAMC1	Laminin subunit gamma 1. (1612 aa)
	MEGF10	Multiple EGF like domains 10. (1178 aa)
	LAMA2	Laminin subunit alpha 2. (3122 aa)
	NTN1	Netrin 1. (604 aa)
	USH2A	Usherin. (5202 aa)
	MEGF9	Multiple EGF like domains 9. (599 aa)
	LAMC3	Laminin subunit gamma 3. (1578 aa)
	LAMB4	Laminin subunit beta 4. (1747 aa)
	LAMB3	Laminin subunit beta 3. (1185 aa)
	LAMB1	Laminin subunit beta 1. (1834 aa)
	ATRNL1	Attractin like 1. (1380 aa)
	STAB1	Stabilin 1. (2572 aa)
	NTN4	Netrin 4. (630 aa)
	CRELD1	Cysteine rich with EGF like domains 1. (432 aa)
	CELSR3	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3316 aa)
	SCARF2	Scavenger receptor class F member 2. (1167 aa)
	NTNG2	Netrin G2. (634 aa)
	LAMC2	Laminin subunit gamma-2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. (1193 aa)
	MEGF11	Multiple EGF like domains 11. (1140 aa)
	AGRN	Agrin. (2071 aa)
	LAMA5	Laminin subunit alpha 5. (3696 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	HSPG2	ENSECAP00000035833	ENSECAP00000054621	Agrin.	Heparan sulfate proteoglycan 2.	0.511
ATRN	MEGF8	ENSECAP00000053262	ENSECAP00000017016	Attractin.	Multiple EGF like domains 8.	0.401
HSPG2	AGRN	ENSECAP00000054621	ENSECAP00000035833	Heparan sulfate proteoglycan 2.	Agrin.	0.511
LAMA1	LAMA2	ENSECAP00000040586	ENSECAP00000022822	Laminin subunit alpha 1.	Laminin subunit alpha 2.	0.929
LAMA1	LAMA3	ENSECAP00000040586	ENSECAP00000039932	Laminin subunit alpha 1.	Laminin subunit alpha 3.	0.574
LAMA1	LAMA5	ENSECAP00000040586	ENSECAP00000038546	Laminin subunit alpha 1.	Laminin subunit alpha 5.	0.619
LAMA1	LAMB1	ENSECAP00000040586	ENSECAP00000007312	Laminin subunit alpha 1.	Laminin subunit beta 1.	0.830
LAMA1	LAMB2	ENSECAP00000040586	ENSECAP00000019891	Laminin subunit alpha 1.	Laminin subunit beta 2.	0.626
LAMA1	LAMB3	ENSECAP00000040586	ENSECAP00000006285	Laminin subunit alpha 1.	Laminin subunit beta 3.	0.626
LAMA1	LAMB4	ENSECAP00000040586	ENSECAP00000003766	Laminin subunit alpha 1.	Laminin subunit beta 4.	0.482
LAMA1	LAMC1	ENSECAP00000040586	ENSECAP00000021019	Laminin subunit alpha 1.	Laminin subunit gamma 1.	0.680
LAMA1	LAMC2	ENSECAP00000040586	ENSECAP00000031292	Laminin subunit alpha 1.	Laminin subunit gamma-2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.	0.530
LAMA1	LAMC3	ENSECAP00000040586	ENSECAP00000000684	Laminin subunit alpha 1.	Laminin subunit gamma 3.	0.564
LAMA1	NTN4	ENSECAP00000040586	ENSECAP00000009827	Laminin subunit alpha 1.	Netrin 4.	0.460
LAMA1	NTNG1	ENSECAP00000040586	ENSECAP00000052279	Laminin subunit alpha 1.	Netrin G1.	0.519
LAMA2	LAMA1	ENSECAP00000022822	ENSECAP00000040586	Laminin subunit alpha 2.	Laminin subunit alpha 1.	0.929
LAMA2	LAMA3	ENSECAP00000022822	ENSECAP00000039932	Laminin subunit alpha 2.	Laminin subunit alpha 3.	0.597
LAMA2	LAMA4	ENSECAP00000022822	ENSECAP00000016800	Laminin subunit alpha 2.	Laminin subunit alpha 4.	0.476
LAMA2	LAMA5	ENSECAP00000022822	ENSECAP00000038546	Laminin subunit alpha 2.	Laminin subunit alpha 5.	0.636
LAMA2	LAMB1	ENSECAP00000022822	ENSECAP00000007312	Laminin subunit alpha 2.	Laminin subunit beta 1.	0.954