(19 nodes) FAD-binding domain, ferredoxin reductase-type network (Equus caballus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	CYB5R1	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (332 aa)
	CYB5R4	Cytochrome b5 reductase 4. (551 aa)
	NDOR1	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (597 aa)
	CYBB	Cytochrome b-245 beta chain. (633 aa)
	CYB5RL	Cytochrome b5 reductase like. (402 aa)
	NOS1	Nitric oxide synthase 1. (1468 aa)
	CYB5R2	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
	NOX5	NADPH oxidase 5. (803 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1247 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1267 aa)
	DUOX1	Dual oxidase 1. (1551 aa)
	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (786 aa)
	NOX3	NADPH oxidase 3. (568 aa)
	NOX1	NADPH oxidase 1. (565 aa)
	DUOX2	Dual oxidase 2. (1545 aa)
	OXNAD1	Oxidoreductase NAD binding domain containing 1. (312 aa)
	NOX4	NADPH oxidase 4. (577 aa)
	POR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)
	CYB5R3	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYB5R1	CYB5R4	ENSECAP00000007992	ENSECAP00000051844	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.470
CYB5R1	POR	ENSECAP00000007992	ENSECAP00000007060	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.535
CYB5R2	CYB5R4	ENSECAP00000034141	ENSECAP00000051844	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.477
CYB5R2	POR	ENSECAP00000034141	ENSECAP00000007060	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.532
CYB5R3	CYB5R4	ENSECAP00000006705	ENSECAP00000051844	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.470
CYB5R3	POR	ENSECAP00000006705	ENSECAP00000007060	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.531
CYB5R4	CYB5R1	ENSECAP00000051844	ENSECAP00000007992	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.470
CYB5R4	CYB5R2	ENSECAP00000051844	ENSECAP00000034141	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.477
CYB5R4	CYB5R3	ENSECAP00000051844	ENSECAP00000006705	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.470
CYB5R4	CYB5RL	ENSECAP00000051844	ENSECAP00000043730	Cytochrome b5 reductase 4.	Cytochrome b5 reductase like.	0.515
CYB5R4	MTRR	ENSECAP00000051844	ENSECAP00000020761	Cytochrome b5 reductase 4.	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	0.436
CYB5R4	NDOR1	ENSECAP00000051844	ENSECAP00000051094	Cytochrome b5 reductase 4.	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.436
CYB5R4	NOS1	ENSECAP00000051844	ENSECAP00000038208	Cytochrome b5 reductase 4.	Nitric oxide synthase 1.	0.436
CYB5R4	NOS2	ENSECAP00000051844	ENSECAP00000022433	Cytochrome b5 reductase 4.	Nitric oxide synthase; Produces nitric oxide (NO).	0.436
CYB5R4	NOS3	ENSECAP00000051844	ENSECAP00000022325	Cytochrome b5 reductase 4.	Nitric oxide synthase; Produces nitric oxide (NO).	0.436
CYB5R4	OXNAD1	ENSECAP00000051844	ENSECAP00000012453	Cytochrome b5 reductase 4.	Oxidoreductase NAD binding domain containing 1.	0.482
CYB5R4	POR	ENSECAP00000051844	ENSECAP00000007060	Cytochrome b5 reductase 4.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.516
CYB5RL	CYB5R4	ENSECAP00000043730	ENSECAP00000051844	Cytochrome b5 reductase like.	Cytochrome b5 reductase 4.	0.515
CYB5RL	POR	ENSECAP00000043730	ENSECAP00000007060	Cytochrome b5 reductase like.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.537
CYBB	DUOX1	ENSECAP00000046091	ENSECAP00000021777	Cytochrome b-245 beta chain.	Dual oxidase 1.	0.610