(10 nodes) Ubiquitin conserved site network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FAU	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (133 aa)
	UBC	Ubiquitin B. (305 aa)
	UBL4A	Ubiquitin like 4A. (159 aa)
	BAG6	BCL2 associated athanogene 6. (1073 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (554 aa)
	UBC-2	Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (305 aa)
	NEDD8	NEDD8 ubiquitin like modifier. (81 aa)
	UBFD1	Ubiquitin family domain containing 1. (363 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG6	FAU	ENSECAP00000011963	ENSECAP00000019440	BCL2 associated athanogene 6.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.459
BAG6	UBC	ENSECAP00000011963	ENSECAP00000002343	BCL2 associated athanogene 6.	Ubiquitin B.	0.426
BAG6	UBC-2	ENSECAP00000011963	ENSECAP00000035675	BCL2 associated athanogene 6.	Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...]	0.432
BAG6	UBL4A	ENSECAP00000011963	ENSECAP00000011241	BCL2 associated athanogene 6.	Ubiquitin like 4A.	0.872
FAU	BAG6	ENSECAP00000019440	ENSECAP00000011963	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	BCL2 associated athanogene 6.	0.459
FAU	NEDD8	ENSECAP00000019440	ENSECAP00000040498	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	NEDD8 ubiquitin like modifier.	0.599
FAU	RPS27A	ENSECAP00000019440	ENSECAP00000016396	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ribosomal protein S27a.	0.997
FAU	UBA52	ENSECAP00000019440	ENSECAP00000018080	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.999
FAU	UBFD1	ENSECAP00000019440	ENSECAP00000040691	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin family domain containing 1.	0.472
FAU	USP14	ENSECAP00000019440	ENSECAP00000020680	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.473
NEDD8	FAU	ENSECAP00000040498	ENSECAP00000019440	NEDD8 ubiquitin like modifier.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.599
NEDD8	RPS27A	ENSECAP00000040498	ENSECAP00000016396	NEDD8 ubiquitin like modifier.	Ribosomal protein S27a.	0.823
NEDD8	UBA52	ENSECAP00000040498	ENSECAP00000018080	NEDD8 ubiquitin like modifier.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.930
NEDD8	UBC	ENSECAP00000040498	ENSECAP00000002343	NEDD8 ubiquitin like modifier.	Ubiquitin B.	0.763
NEDD8	UBC-2	ENSECAP00000040498	ENSECAP00000035675	NEDD8 ubiquitin like modifier.	Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...]	0.763
NEDD8	UBFD1	ENSECAP00000040498	ENSECAP00000040691	NEDD8 ubiquitin like modifier.	Ubiquitin family domain containing 1.	0.523
NEDD8	UBL4A	ENSECAP00000040498	ENSECAP00000011241	NEDD8 ubiquitin like modifier.	Ubiquitin like 4A.	0.529
NEDD8	USP14	ENSECAP00000040498	ENSECAP00000020680	NEDD8 ubiquitin like modifier.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.700
RPS27A	FAU	ENSECAP00000016396	ENSECAP00000019440	Ribosomal protein S27a.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.997
RPS27A	NEDD8	ENSECAP00000016396	ENSECAP00000040498	Ribosomal protein S27a.	NEDD8 ubiquitin like modifier.	0.823