STRINGSTRING
PLPP7 PLPP7 DHCR24 DHCR24 SC5D SC5D FDPS FDPS GGPS1 GGPS1 ARV1 ARV1 PMVK PMVK ACAT2 ACAT2 EBP EBP DHCR7 DHCR7 RUSC1 RUSC1 IDI1 IDI1 HSD17B7 HSD17B7 LBR LBR TM7SF2 TM7SF2 EBPL EBPL SREBF1 SREBF1 MVK MVK PLPP6 PLPP6 CYP51A1 CYP51A1 LSS LSS HMGCR HMGCR FDFT1 FDFT1 MVD MVD NSDHL NSDHL HMGCS1 HMGCS1 MSMO1 MSMO1 SQLE SQLE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLPP7Phospholipid phosphatase 7 (inactive). (152 aa)
DHCR2424-dehydrocholesterol reductase. (516 aa)
SC5DLathosterol oxidase-like protein; Belongs to the sterol desaturase family. (299 aa)
FDPSUncharacterized protein; Belongs to the FPP/GGPP synthase family. (420 aa)
GGPS1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (299 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (271 aa)
PMVKPhosphomevalonate kinase. (192 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
EBP3-beta-hydroxysteroid-Delta(8) Delta(7)-isomerase-like protein. (230 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
RUSC1RUN and SH3 domain containing 1. (905 aa)
IDI1Isopentenyl-diphosphate delta isomerase 1. (227 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (333 aa)
LBRLamin B receptor. (617 aa)
TM7SF2Transmembrane 7 superfamily member 2. (415 aa)
EBPLEBP like. (205 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1740 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (541 aa)
PLPP6Phospholipid phosphatase 6. (294 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (579 aa)
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (807 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (901 aa)
FDFT1Farnesyl-diphosphate farnesyltransferase 1. (485 aa)
MVDMevalonate diphosphate decarboxylase. (497 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating-like protein; Belongs to the 3-beta-HSD family. (361 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
MSMO1C-4 methylsterol oxidase-like protein; Belongs to the sterol desaturase family. (293 aa)
SQLESqualene epoxidase. (576 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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