STRINGSTRING
CRH CRH CD55 CD55 ADGRL1 ADGRL1 RAMP3 RAMP3 LOC102150647 LOC102150647 ENSECAP00000044034 ENSECAP00000044034 GNB1 GNB1 PTCH2 PTCH2 UCN2 UCN2 GNB5 GNB5 LOC100064538 LOC100064538 GCG GCG GNG2 GNG2 ADGRL2 ADGRL2 SCTR SCTR LOC100053318 LOC100053318 ENSECAP00000045558 ENSECAP00000045558 CRHR2 CRHR2 VIPR1 VIPR1 CALCB CALCB ADM ADM UCN UCN PALMD PALMD FZD10 FZD10 CALCR CALCR GNG10 GNG10 RAMP2 RAMP2 PTH2 PTH2 ADCYAP1R1 ADCYAP1R1 GIP GIP GNB4 GNB4 CALCA-2 CALCA-2 CALCA CALCA PTH1R PTH1R RAMP1 RAMP1 SCT SCT GCGR GCGR LOC100064396 LOC100064396 ADGRE3 ADGRE3 GNG3 GNG3 GNB3 GNB3 CALCRL CALCRL VIP VIP PTH2R PTH2R PTHLH PTHLH GHRHR GHRHR F6VD36_HORSE F6VD36_HORSE GNGT2 GNGT2 GIPR GIPR GNB2 GNB2 GLP1R GLP1R CRHBP CRHBP GNG13 GNG13 GLP2R GLP2R PTH PTH CRHR1 CRHR1 ADM2 ADM2 UCN3 UCN3 LOC100064510 LOC100064510 ADGRE5 ADGRE5 F6T997_HORSE F6T997_HORSE IAPP IAPP GNG11 GNG11 GNG8 GNG8 F6RMT8_HORSE F6RMT8_HORSE ADCYAP1 ADCYAP1 ADGRE1 ADGRE1 VIPR2 VIPR2 GNG4 GNG4 GNGT1 GNGT1 ADGRL3 ADGRL3 FAP FAP GNG12 GNG12 GNG5 GNG5 GNG7 GNG7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRHCorticotropin releasing hormone. (232 aa)
CD55Uncharacterized protein. (411 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1473 aa)
RAMP3Uncharacterized protein. (224 aa)
LOC102150647Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (657 aa)
ENSECAP00000044034Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (612 aa)
GNB1G protein subunit beta 1. (360 aa)
PTCH2Patched 2. (1207 aa)
UCN2Urocortin 2. (112 aa)
GNB5G protein subunit beta 5. (395 aa)
LOC100064538Uncharacterized protein. (788 aa)
GCGGlucagon. (232 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (108 aa)
ADGRL2Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1489 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (523 aa)
LOC100053318Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (711 aa)
ENSECAP00000045558Uncharacterized protein. (331 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (559 aa)
CALCBCalcitonin gene-related peptide 2; CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (By similarity); Belongs to the calcitonin family. (132 aa)
ADMAdrenomedullin. (309 aa)
UCNUrocortin. (126 aa)
PALMDPalmdelphin. (551 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (475 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RAMP2Receptor activity modifying protein 2. (181 aa)
PTH2Parathyroid hormone 2. (98 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (566 aa)
GIPGastric inhibitory polypeptide. (145 aa)
GNB4G protein subunit beta 4. (340 aa)
CALCA-2Calcitonin gene-related peptide 1; CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP (By similarity). (173 aa)
CALCACalcitonin. (134 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (586 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
SCTGLUCAGON domain-containing protein. (57 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (654 aa)
LOC100064396Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (781 aa)
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (594 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB3G protein subunit beta 3. (340 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
VIPVasoactive intestinal peptide. (171 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
PTHLHParathyroid hormone-related protein; Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity o [...] (177 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
F6VD36_HORSEUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (424 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (86 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
GNB2G protein subunit beta 2. (340 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
GNG13G protein subunit gamma 13. (67 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (710 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa)
CRHR1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (415 aa)
ADM2Adrenomedullin 2. (142 aa)
UCN3Urocortin 3. (167 aa)
LOC100064510Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (796 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (860 aa)
F6T997_HORSEUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (690 aa)
IAPPIslet amyloid polypeptide. (119 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
F6RMT8_HORSEUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (403 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (170 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (1233 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (468 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (164 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADGRL3Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1580 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (788 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (341 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.