19 items (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EXOSC2	Exosome component 2. (342 aa)
	EXOSC7	Exosome component 7. (321 aa)
	DIS3L	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1055 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	DCP1A	Decapping mRNA 1A. (580 aa)
	EXOSC5	Exosome component 5. (235 aa)
	DIS3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
	EXOSC6	Exosome component 6. (272 aa)
	TNPO1	Transportin 1. (898 aa)
	TNPO2	Transportin 2. (887 aa)
	EXOSC1	Exosome component 1. (195 aa)
	ZFP36	Uncharacterized protein. (662 aa)
	DIS3L2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (905 aa)
	DCP2	Decapping mRNA 2. (422 aa)
	EXOSC9	Exosome component 9. (440 aa)
	EXOSC8	Exosome component 8. (276 aa)
	EXOSC4	Exosome component 4. (245 aa)
	EXOSC3	Exosome component 3. (275 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCP1A	DCP2	ENSECAP00000022294	ENSECAP00000038639	Decapping mRNA 1A.	Decapping mRNA 2.	0.999
DCP1A	DIS3	ENSECAP00000022294	ENSECAP00000021549	Decapping mRNA 1A.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.594
DCP1A	DIS3L	ENSECAP00000022294	ENSECAP00000005829	Decapping mRNA 1A.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.647
DCP1A	DIS3L2	ENSECAP00000022294	ENSECAP00000037806	Decapping mRNA 1A.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.554
DCP1A	EXOSC1	ENSECAP00000022294	ENSECAP00000049847	Decapping mRNA 1A.	Exosome component 1.	0.590
DCP1A	EXOSC2	ENSECAP00000022294	ENSECAP00000031865	Decapping mRNA 1A.	Exosome component 2.	0.638
DCP1A	EXOSC3	ENSECAP00000022294	ENSECAP00000030679	Decapping mRNA 1A.	Exosome component 3.	0.631
DCP1A	EXOSC4	ENSECAP00000022294	ENSECAP00000011336	Decapping mRNA 1A.	Exosome component 4.	0.657
DCP1A	EXOSC5	ENSECAP00000022294	ENSECAP00000021686	Decapping mRNA 1A.	Exosome component 5.	0.669
DCP1A	EXOSC6	ENSECAP00000022294	ENSECAP00000032558	Decapping mRNA 1A.	Exosome component 6.	0.588
DCP1A	EXOSC9	ENSECAP00000022294	ENSECAP00000022319	Decapping mRNA 1A.	Exosome component 9.	0.604
DCP1A	TNPO1	ENSECAP00000022294	ENSECAP00000032961	Decapping mRNA 1A.	Transportin 1.	0.492
DCP1A	ZFP36	ENSECAP00000022294	ENSECAP00000045220	Decapping mRNA 1A.	Uncharacterized protein.	0.656
DCP2	DCP1A	ENSECAP00000038639	ENSECAP00000022294	Decapping mRNA 2.	Decapping mRNA 1A.	0.999
DCP2	DIS3	ENSECAP00000038639	ENSECAP00000021549	Decapping mRNA 2.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.664
DCP2	DIS3L	ENSECAP00000038639	ENSECAP00000005829	Decapping mRNA 2.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.722
DCP2	DIS3L2	ENSECAP00000038639	ENSECAP00000037806	Decapping mRNA 2.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.594
DCP2	EXOSC1	ENSECAP00000038639	ENSECAP00000049847	Decapping mRNA 2.	Exosome component 1.	0.687
DCP2	EXOSC2	ENSECAP00000038639	ENSECAP00000031865	Decapping mRNA 2.	Exosome component 2.	0.722
DCP2	EXOSC3	ENSECAP00000038639	ENSECAP00000030679	Decapping mRNA 2.	Exosome component 3.	0.661