STRINGSTRING
NUP107 NUP107 RANBP2 RANBP2 NDC80 NDC80 NDE1 NDE1 NUF2 NUF2 NSL1 NSL1 CENPI CENPI MAPRE1 MAPRE1 AURKB AURKB PAFAH1B1 PAFAH1B1 UBE2C UBE2C DYNC1I1 DYNC1I1 NUP98 NUP98 CDCA8 CDCA8 CENPA CENPA KIF18A KIF18A FAM89A FAM89A PPP2R5B PPP2R5B CKAP5 CKAP5 MAPRE3 MAPRE3 CENPU CENPU MEIOC MEIOC CDC20B CDC20B CENPO CENPO BUB1 BUB1 PPP1CC PPP1CC SPC24 SPC24 PLK1 PLK1 ANAPC4 ANAPC4 CENPC CENPC NUP43 NUP43 TMEM219 TMEM219 CENPK CENPK CENPP CENPP ANAPC2 ANAPC2 NUP85 NUP85 KIF2C KIF2C CDC20 CDC20 CDC16 CDC16 NUP133 NUP133 NUDC NUDC AURKC AURKC BUB1B BUB1B NUP160 NUP160 CLASP1 CLASP1 CENPM CENPM ANAPC7 ANAPC7 MAD2L1 MAD2L1 CENPF CENPF ANAPC5 ANAPC5 RANGAP1 RANGAP1 ANAPC10 ANAPC10 SPC25 SPC25 ITGB3BP ITGB3BP UBE2S UBE2S DYNC1H1 DYNC1H1 LOC111767487 LOC111767487 CENPH CENPH KNTC1 KNTC1 DYNLL2 DYNLL2 NUP37 NUP37 RCC2 RCC2 CLIP1 CLIP1 CDC27 CDC27 TAOK1 TAOK1 CENPE CENPE CENPL CENPL PPP2R5C PPP2R5C UBE2D1 UBE2D1 ENSECAP00000032081 ENSECAP00000032081 ZWINT ZWINT PPP2R5D PPP2R5D ENSECAP00000034097 ENSECAP00000034097 KNL1 KNL1 MAPRE2 MAPRE2 SKA1 SKA1 INCENP INCENP BUB3 BUB3 FAM89B FAM89B ZWILCH ZWILCH CLASP2 CLASP2 ERCC6L2 ERCC6L2 CDC26 CDC26 ENSECAP00000039817 ENSECAP00000039817 MAD1L1 MAD1L1 CENPS CENPS SPDL1 SPDL1 MTUS2 MTUS2 CLIP2 CLIP2 SEC13 SEC13 DYNC1LI2 DYNC1LI2 TAOK2 TAOK2 PPP2R1B PPP2R1B ANAPC1 ANAPC1 KIF2A KIF2A AHCTF1 AHCTF1 XPO1 XPO1 PPP2R5A PPP2R5A PPP2R1A PPP2R1A CENPN CENPN NDEL1 NDEL1 ENSECAP00000052394 ENSECAP00000052394 SGO1 SGO1 ZW10 ZW10 B9D2 B9D2 CDC23 CDC23 PPP2CB PPP2CB PPP2R5E PPP2R5E CENPQ CENPQ DYNC1LI1 DYNC1LI1 ANAPC11 ANAPC11 MIS12 MIS12 ERCC6L ERCC6L F6TWR4_HORSE F6TWR4_HORSE KIF2B KIF2B ANAPC16 ANAPC16 LOC100050599 LOC100050599 SGO2 SGO2 LOC100146589 LOC100146589 DYNLL1 DYNLL1 DYNC1I2 DYNC1I2 BIRC5 BIRC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (931 aa)
RANBP2RAN binding protein 2. (3309 aa)
NDC80NDC80 kinetochore complex component. (644 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (281 aa)
CENPICentromere protein I. (744 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (285 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
UBE2CUbiquitin conjugating enzyme E2 C. (79 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
NUP98Nucleoporin 98. (1817 aa)
CDCA8Cell division cycle associated 8. (280 aa)
CENPACentromere protein A. (136 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (895 aa)
FAM89AFamily with sequence similarity 89 member A. (168 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (542 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
MAPRE3Uncharacterized protein. (281 aa)
CENPUCentromere protein U. (414 aa)
MEIOCMeiosis specific with coiled-coil domain. (1036 aa)
CDC20BCell division cycle 20B. (515 aa)
CENPOCentromere protein O. (300 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1076 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (197 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
CENPCCentromere protein C. (955 aa)
NUP43Nucleoporin 43. (380 aa)
TMEM219Transmembrane protein 219. (272 aa)
CENPKCentromere protein K. (271 aa)
CENPPCentromere protein P. (289 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (823 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (710 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
CDC20Cell division cycle 20. (499 aa)
CDC16Cell division cycle 16. (630 aa)
NUP133Nucleoporin 133. (1156 aa)
NUDCNuclear distribution C, dynein complex regulator. (385 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (275 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1063 aa)
NUP160Nucleoporin 160. (1581 aa)
CLASP1Cytoplasmic linker associated protein 1. (1534 aa)
CENPMCentromere protein M. (180 aa)
ANAPC7Anaphase promoting complex subunit 7. (598 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
CENPFCentromere protein F. (3100 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
RANGAP1Ran GTPase activating protein 1. (590 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (192 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4646 aa)
LOC111767487Anaphase promoting complex subunit 1. (1944 aa)
CENPHCentromere protein H. (247 aa)
KNTC1Kinetochore associated 1. (2207 aa)
DYNLL2Uncharacterized protein. (313 aa)
NUP37Nucleoporin 37. (366 aa)
RCC2Regulator of chromosome condensation 2. (561 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1970 aa)
CDC27Cell division cycle 27. (836 aa)
TAOK1TAO kinase 1. (1001 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2767 aa)
CENPLCentromere protein L. (346 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (691 aa)
UBE2D1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSECAP00000032081Uncharacterized protein. (340 aa)
ZWINTZW10 interacting kinetochore protein. (332 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (697 aa)
ENSECAP00000034097Dynein light chain. (85 aa)
KNL1Kinetochore scaffold 1. (2351 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (405 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (271 aa)
INCENPInner centromere protein. (915 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
FAM89BFamily with sequence similarity 89 member B. (192 aa)
ZWILCHZwilch kinetochore protein. (636 aa)
CLASP2Cytoplasmic linker associated protein 2. (1543 aa)
ERCC6L2Uncharacterized protein. (1549 aa)
CDC26Cell division cycle 26. (85 aa)
ENSECAP00000039817Uncharacterized protein. (168 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (754 aa)
CENPSCentromere protein S. (138 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (604 aa)
MTUS2Microtubule associated scaffold protein 2. (1379 aa)
CLIP2CAP-Gly domain containing linker protein 2. (1044 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (325 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (491 aa)
TAOK2TAO kinase 2. (1295 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (783 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
AHCTF1AT-hook containing transcription factor 1. (2350 aa)
XPO1Exportin 1. (1081 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (519 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (666 aa)
CENPNCentromere protein N. (339 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (438 aa)
ENSECAP00000052394SER_THR_PHOSPHATASE domain-containing protein. (193 aa)
SGO1Shugoshin 1. (529 aa)
ZW10Zw10 kinetochore protein. (779 aa)
B9D2B9 domain containing 2. (175 aa)
CDC23Cell division cycle 23. (597 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (475 aa)
CENPQCentromere protein Q. (270 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (606 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
MIS12MIS12 kinetochore complex component. (206 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1244 aa)
F6TWR4_HORSEUncharacterized protein. (142 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (636 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
LOC100050599Uncharacterized protein. (281 aa)
SGO2Shugoshin 2. (1357 aa)
LOC100146589Uncharacterized protein. (205 aa)
DYNLL1Dynein light chain. (89 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
BIRC5Baculoviral IAP repeat containing 5. (226 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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