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IRAK1 | Interleukin 1 receptor associated kinase 1. (805 aa) | ||||
ARHGEF10 | Rho guanine nucleotide exchange factor 10. (1408 aa) | ||||
TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa) | ||||
UBE2D3 | Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) | ||||
ARHGEF25 | Rho guanine nucleotide exchange factor 25. (619 aa) | ||||
ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1544 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
TRAF1 | TNF receptor-associated factor. (415 aa) | ||||
ARHGEF7 | Rho guanine nucleotide exchange factor 7. (893 aa) | ||||
PRDM4 | PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa) | ||||
ARHGEF16 | Rho guanine nucleotide exchange factor 16. (749 aa) | ||||
FGD3 | FYVE, RhoGEF and PH domain containing 3. (730 aa) | ||||
PPOX | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa) | ||||
FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (283 aa) | ||||
OMG | Oligodendrocyte myelin glycoprotein. (443 aa) | ||||
USP4 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (1059 aa) | ||||
SMPD2 | Sphingomyelin phosphodiesterase 2. (423 aa) | ||||
MADD | MAP kinase activating death domain. (1647 aa) | ||||
GNA13 | G protein subunit alpha 13. (377 aa) | ||||
NGFR | Nerve growth factor receptor. (435 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) | ||||
LOC111768857 | Uncharacterized protein. (642 aa) | ||||
RPS27A | Ribosomal protein S27a. (156 aa) | ||||
SPPL2C | Signal peptide peptidase like 2C. (682 aa) | ||||
CLIP4 | CAP-Gly domain containing linker protein family member 4. (748 aa) | ||||
SESTD1 | SEC14 and spectrin domain containing 1. (718 aa) | ||||
RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (535 aa) | ||||
KXD1 | KxDL motif containing 1. (194 aa) | ||||
PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5. (1080 aa) | ||||
LINGO2 | Uncharacterized protein. (606 aa) | ||||
APH1B | Aph-1 homolog B, gamma-secretase subunit. (524 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (615 aa) | ||||
BCL2L11 | BCL2 like 11. (289 aa) | ||||
MCF2 | MCF.2 cell line derived transforming sequence. (1177 aa) | ||||
CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) | ||||
PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (619 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1613 aa) | ||||
VAV2 | Vav guanine nucleotide exchange factor 2. (879 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (475 aa) | ||||
BIRC2 | Baculoviral IAP repeat containing 3. (604 aa) | ||||
LINGO1 | Leucine rich repeat and Ig domain containing 1. (620 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (464 aa) | ||||
SPATA2 | Spermatogenesis associated 2. (520 aa) | ||||
ARHGEF10L | Rho guanine nucleotide exchange factor 10 like. (1280 aa) | ||||
PSENEN | Presenilin enhancer, gamma-secretase subunit. (101 aa) | ||||
WDR31 | WD repeat domain 31. (537 aa) | ||||
OPTN | Optineurin. (574 aa) | ||||
TMEM198 | Transmembrane protein 198. (360 aa) | ||||
UBE2D4 | Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa) | ||||
AATF | Apoptosis antagonizing transcription factor. (566 aa) | ||||
ARHGEF17 | Rho guanine nucleotide exchange factor 17. (2063 aa) | ||||
MCF2L2 | MCF.2 cell line derived transforming sequence-like 2. (1063 aa) | ||||
CLIP3 | CAP-Gly domain containing linker protein 3. (622 aa) | ||||
BIRC7 | Baculoviral IAP repeat containing 7. (282 aa) | ||||
TRIO | Trio Rho guanine nucleotide exchange factor. (3107 aa) | ||||
ARHGDIA | Rho GDP dissociation inhibitor alpha. (204 aa) | ||||
UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa) | ||||
SQSTM1 | Sequestosome 1. (440 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (212 aa) | ||||
NET1 | Neuroepithelial cell transforming 1. (596 aa) | ||||
CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (510 aa) | ||||
ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1687 aa) | ||||
MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
CASP3 | Caspase-3-like protein; Belongs to the peptidase C14A family. (277 aa) | ||||
RACK1 | WD_REPEATS_REGION domain-containing protein. (317 aa) | ||||
ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1560 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (543 aa) | ||||
TGM3 | Transglutaminase 3. (694 aa) | ||||
CASP10 | Caspase 10; Belongs to the peptidase C14A family. (478 aa) | ||||
F6SDY4_HORSE | TNFR-Cys domain-containing protein. (296 aa) | ||||
TNFRSF10B | Uncharacterized protein. (423 aa) | ||||
ITGB3BP | Integrin subunit beta 3 binding protein. (192 aa) | ||||
UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) | ||||
LOC111768857-2 | Uncharacterized protein. (1341 aa) | ||||
OTUD1 | OTU deubiquitinase 1. (485 aa) | ||||
LOC102150834 | Uncharacterized protein. (430 aa) | ||||
ARHGEF19 | Rho guanine nucleotide exchange factor 19. (989 aa) | ||||
XIAP | X-linked inhibitor of apoptosis. (494 aa) | ||||
SPPL2A | Signal peptide peptidase like 2A. (540 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (822 aa) | ||||
ABR | ABR activator of RhoGEF and GTPase. (1191 aa) | ||||
ARHGEF1 | Rho guanine nucleotide exchange factor 1. (1040 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (655 aa) | ||||
ARHGEF37 | Rho guanine nucleotide exchange factor 37. (693 aa) | ||||
LOC100067370 | Uncharacterized protein. (461 aa) | ||||
MCF2L | MCF.2 cell line derived transforming sequence like. (1185 aa) | ||||
ARHGEF9 | Cdc42 guanine nucleotide exchange factor 9. (1167 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (654 aa) | ||||
UBE2D1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) | ||||
TIAM2 | T cell lymphoma invasion and metastasis 2. (1708 aa) | ||||
BEX3 | Brain expressed X-linked 3. (255 aa) | ||||
ULK2 | Unc-51 like autophagy activating kinase 2. (1059 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (770 aa) | ||||
CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) | ||||
APH1A | Aph-1 homolog A, gamma-secretase subunit. (274 aa) | ||||
ENSECAP00000031719 | Uncharacterized protein. (438 aa) | ||||
OTULIN | OTU deubiquitinase with linear linkage specificity. (350 aa) | ||||
ARHGEF33 | Rho guanine nucleotide exchange factor 33. (889 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (569 aa) | ||||
ADAM17 | ADAM metallopeptidase domain 17. (891 aa) | ||||
ARHGEF26 | Rho guanine nucleotide exchange factor 26. (797 aa) | ||||
AKAP13 | A-kinase anchoring protein 13. (2905 aa) | ||||
UBC-2 | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (305 aa) | ||||
TGM6 | Transglutaminase 6. (708 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) | ||||
ARHGEF15 | Rho guanine nucleotide exchange factor 15. (852 aa) | ||||
ECT2L | Epithelial cell transforming 2 like. (959 aa) | ||||
LOC111771929 | Rho guanine nucleotide exchange factor 4. (483 aa) | ||||
OTULINL | OTU deubiquitinase with linear linkage specificity like. (366 aa) | ||||
KALRN | Kalirin RhoGEF kinase. (2987 aa) | ||||
ECT2 | Epithelial cell transforming 2. (1042 aa) | ||||
ARHGEF18 | Uncharacterized protein. (1423 aa) | ||||
NCSTN | Nicastrin. (709 aa) | ||||
LOC111776006 | Uncharacterized protein. (380 aa) | ||||
TNFSF10 | Tumor necrosis factor ligand superfamily member. (289 aa) | ||||
USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (665 aa) | ||||
PLEKHG2 | Pleckstrin homology and RhoGEF domain containing G2. (1423 aa) | ||||
FGD4 | FYVE, RhoGEF and PH domain containing 4. (940 aa) | ||||
ARHGEF39 | Rho guanine nucleotide exchange factor 39. (335 aa) | ||||
YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (312 aa) | ||||
TNFAIP3 | TNF alpha induced protein 3. (794 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) | ||||
BAG4 | BCL2 associated athanogene 4. (456 aa) | ||||
NGF | Nerve growth factor; Belongs to the NGF-beta family. (294 aa) | ||||
LOC100058940 | DUF4203 domain-containing protein. (350 aa) | ||||
NFATC4 | Nuclear factor of activated T cells 4. (932 aa) | ||||
ARHGEF38 | Rho guanine nucleotide exchange factor 38. (778 aa) | ||||
MAG | Myelin associated glycoprotein. (626 aa) | ||||
FGD1 | FYVE, RhoGEF and PH domain containing 1. (960 aa) | ||||
SMPD3 | Sphingomyelin phosphodiesterase 3. (658 aa) | ||||
MAP3K20 | Uncharacterized protein. (850 aa) | ||||
SHARPIN | SHANK associated RH domain interactor. (384 aa) | ||||
NSMAF | Neutral sphingomyelinase activation associated factor. (920 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
LOC100071666 | RanBP2-type domain-containing protein. (413 aa) | ||||
NAIP | NLR family apoptosis inhibitory protein. (1402 aa) | ||||
UBC | Ubiquitin B. (305 aa) | ||||
TAX1BP1 | Tax1 binding protein 1. (816 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (470 aa) | ||||
RTN4R | Reticulon 4 receptor. (473 aa) | ||||
NGEF | Neuronal guanine nucleotide exchange factor. (787 aa) | ||||
SMPD5 | Endo/exonuclease/phosphatase domain-containing protein. (477 aa) | ||||
RTN4 | Reticulon. (1196 aa) | ||||
ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) | ||||
ITSN1 | Intersectin 1. (1745 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (312 aa) | ||||
FAS | Fas cell surface death receptor. (365 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
FGD2 | FYVE, RhoGEF and PH domain containing 2. (657 aa) | ||||
F7CNV6_HORSE | Uncharacterized protein. (1071 aa) | ||||
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1176 aa) | ||||
STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) | ||||
BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
SPPL2B | Signal peptide peptidase like 2B. (565 aa) | ||||
PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1757 aa) | ||||
MIB2 | Mindbomb E3 ubiquitin protein ligase 2. (957 aa) | ||||
ARHGEF3 | Rho guanine nucleotide exchange factor 3. (634 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (1049 aa) | ||||
VAV1 | Vav guanine nucleotide exchange factor 1. (918 aa) | ||||
VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) | ||||
ENSECAP00000044533 | Ubiquitin-like domain-containing protein. (180 aa) |